Only FUNCTIONAL and ORF V-GENEs are shown.
IGIV
genes |
FR1-IMGT
1 to 26 |
CDR1-IMGT
27 to 38 |
FR2-IMGT
39 to 55 |
CDR2-IMGT
56 to 65 |
FR3-IMGT
66 to 104 |
CDR3-IMGT
(germline V-GENE) 105 to 116 |
(26) | (6-9,11) | (16,17) | (3,9,10,15(2)) | (36,37) | (8,10-12) | |
IGIV1S1 IGIV1S2 IGIV1S3 IGIV1S4 IGIV1S5 |
8 8 9 11 |
3 | -3 (aa 73, 81, 82) | 12 11 (1) 11 (1) 8 (1) 8 (1) |
||
IGIV2S1 IGIV2S2 IGIV2S3 IGIV2S4 IGIV2S5 IGIV2S6 IGIV2S7 IGIV2S8 IGIV2S9 IGIV2S11 IGIV2S12 IGIV2S13 |
6 6 6 6 6 6 6 6 7 6 6 |
-1 (aa 45) |
15 (2) 15 (2) 15 (2) 15 (2) 10 10 10 10 9 10 10 10 |
-2 (aa 73, 81) -2 (aa 73, 81) -2 (aa 73, 81) -2 (aa 73, 81) -2 (aa 73, 81) -2 (aa 73, 81) -2 (aa 73, 81) -2 (aa 73, 81) -3 (aa 73, 74, 81) -2 (aa 73, 81) -3 (aa 73, 74, 81) -2 (aa 73, 81) |
11 11 11 10 (1) 10 (1) 10 (1) 10 (1) 11 11 11 11 11 |
(1) | Probable CDR3-IMGT length, but needs to be confirmed with germline sequences. |
(2) | Insertion of 5 amino acids between positions 60 and 61 in CDR2-IMGT (60A, 60B, 60C, 60D and 60E). |
Created: 08/09/1999
Last updated: Friday, 22-Sep-2023 18:17:41 CEST
Authors: Sylvaine Artero
and Nathalie Bosc