Only FUNCTIONAL and ORF V-GENEs are shown.
IGHV genes |
FR1-IMGT 1 to 26 |
CDR1-IMGT 27 to 38 |
FR2-IMGT 39 to 55 |
CDR2-IMGT 56 to 65 |
FR3-IMGT 66 to 104 |
CDR3-IMGT (germline V-GENE) 105 to 115 |
(22-25) | (7,8,12) | (17) | (7-9) | (36,38) | (2,3) | |
IGHV1S1 | -1 (aa 10) | 8 | 8 | -1 (aa 73) | (3) | |
IGHV1S2 to IGHV1S5 |
-1 (aa 10) | 8 | 8 | (2)* | ||
IGHV1S6 | -1 (aa 10) | 8 | 7 | -1 (aa 73) | (2)* | |
IGHV1S7 to IGHV1S8 |
-1 (aa 10) | 8 | 8 | -1 (aa 73) | (2)* | |
IGHV1S9 | -1 (aa 10) | 8 | 7 | -1 (aa 73) | (2)* | |
IGHV1S10 | -1 (aa 10) | 8 | 9 | -1 (aa 73) | (2)* | |
IGHV1S11 | -1 (aa 10) | 8 | 7 | -1 (aa 73) | (2)* | |
IGHV1S6 to IGHV1S18 |
-1 (aa 10) | 8 | 8 | -1 (aa 73) | (2)* | |
IGHV2S1 | -3 (aa 1,2,10) | 8 | 7 | -1 (aa 73) | (2)* | |
IGHV2S2 | -2 (aa 1,10) | 8 | 7 | -1 (aa 73) | (2)* | |
IGHV2S3 | -2 (aa 1,10) | 8 | 2 | -1 (aa 73) | (2)* | |
IGHV2S4 | -2 (aa 1,10) | 8 | 7 | -1 (aa 73) | (2)* | |
IGHV2S5 | -4 (aa 1,2,3,10) | 8 | 7 | -1 (aa 73) | (2)* | |
IGHV2S6 | -3 (aa 1,2,10) | 8 | 7 | -1 (aa 73) | (2)* | |
IGHV3S1 to IGHV3S2 |
-1 (aa 10) | 12 | 7 | -1 (aa 73) | (2)* | |
IGHV4S1 | -3 (aa 1,2,10) | 8 | 7 | -3 (aa 73,81,82) | (2)* | |
IGHV5S1 | -1 (aa 10) | 8 | 8 | -1 (aa 73) | (2)* | |
IGHV6S1 | -1 (aa 10) | 7 | 7 | -1 (aa 73) | (2)* | |
IGHV7S1 | -1 (aa 10) | 12 | 7 | (2)* | ||
IGHV8S1 | -1 (aa 10) | 7 | 7 | -1 (aa 73) | (2)* | |
IGHV9S1 to IGHV9S2 |
-1 (aa 10) | 8 | 8 | -1 (aa 73) | (2)* |
* | Probable CDR3-IMGT length, but needs to be confirmed with germline sequences. |
Created: 22/07/2003
Author: Delphine Guiraudou