Only FUNCTIONAL and ORF V-GENEs are shown.
| IGHV
 genes  | 
FR1-IMGT
 1 to 26  | 
CDR1-IMGT
 27 to 38  | 
FR2-IMGT
 39 to 55  | 
CDR2-IMGT
 56 to 65  | 
FR3-IMGT
 66 to 104  | 
CDR3-IMGT
 (germline V-GENE) 105 to 115  | 
| (25) | (8) | (17) | (7,8) | (38) | (3) (1) | |
| IGHV1S1 IGHV1S2  | 
-1 (aa 10) | 8 | 8 7  | 
-1 (aa 73) | 3 (1) | 
The proteolytic cleavage site between the leader peptide and the V-REGION is putative and the assignment of amino acid 1 to one or the other region is uncertain.
IMGT note:
| (1) | Probable CDR3-IMGT length but needs to be confirmed with germline sequences. | 
Created: 30/07/2002
Author: Nathalie Bosc