Only FUNCTIONAL and ORF V-GENEs are shown.
IGHV
subgroup |
FR1-IMGT
1 to 26 |
CDR1-IMGT
27 to 38 |
FR2-IMGT
39 to 55 |
CDR2-IMGT
56 to 65 |
FR3-IMGT
66 to 104 |
CDR3-IMGT
(germline V-GENE) 105 to 115 |
(25) | (8,10) | (17) | (7,8) | (38) | (2) (1) | |
1 | -1 (aa 10) | 8 | 8 | -1 (aa 73) | 2 (1) | |
2 | -1 (aa 10) | 10 | 7 | -1 (aa 73) | 2 (1) |
The proteolytic cleavage site between the leader peptide and the V-REGION is putative and the assignment of amino acid 1 to one or the other region is uncertain.
IMGT note:
(1) | Probable CDR3-IMGT lenght but needs to be confirmed with germline sequences. |
Created: 08/09/1999
Author: Sylvaine Artero