Only FUNCTIONAL and ORF V-GENEs are shown.
| IGHV genes | FR1-IMGT 1 to 26 | CDR1-IMGT 27 to 38 | FR2-IMGT 39 to 55 | CDR2-IMGT 56 to 65 | FR3-IMGT 66 to 104 | CDR3-IMGT (germline V-GENE) 105 to 115 | 
| (25) | (8) | (17) | (8,9) | (38) | (3) (1) | |
| IGHV1S1 IGHV1S2 IGHV1S3 IGHV1S4 | -1 (aa 10) | 8 | 8 8 9 8 | -1 (aa 73) | 3 (1) | 
The proteolytic cleavage site between the leader peptide and the V-REGION is putative and the assignment of amino acid 1 to one or the other region is uncertain.
IMGT note:
| (1) | Probable CDR3-IMGT length but needs to be confirmed with germline sequences. | 
Created: 01/08/2002
Author: Nathalie Bosc