FR-IMGT and CDR-IMGT lengths: Atlantic salmon (Salmo salar)

Only FUNCTIONAL and ORF V-GENEs are shown.

IGHV
genes		 FR1-IMGT
1 to 26		 CDR1-IMGT
27 to 38		 FR2-IMGT
39 to 55		 CDR2-IMGT
56 to 65		 FR3-IMGT
66 to 104		 CDR3-IMGT
(germline V-GENE)
105 to 115
(24 to 27) (7,8,12) (17) (6 to 8) (36 to 38) (2,3)
IGHV1S1
IGHV1S2		 -1 (aa 10) 8   7
8		 -1 (aa 73) 2 (1)
IGHV2S1
IGHV2S2
IGHV2S3		 +2 (aa 6A,6B)
-1 (aa 10)		 8   6
6
8		 -1 (aa 73) 2 (1)
IGHV3S1 +2 (aa 6A,6B)
-1 (aa 10)		 8   8 -1 (aa 73) 2 (1)
IGHV5S1
IGHV5S5
IGHV5S6
IGHV5S7
IGHV5S8
IGHV5S9
IGHV5S10		 -1 (aa 10) 8   6
8
8
8
6
6
6		 -1 (aa 73) 3
IGHV6S1
IGHV6S2
IGHV6S3
IGHV6S4
IGHV6S5		 -2 (aa 1,10) 7   7
7
7
6
6		 -1 (aa 73) 2 (1)
IGHV7S1 -1 (aa 10) 12   7 -1 (aa 73) 2 (1)
IGHV8S1
IGHV8S2		   8   7 -3 (aa 73,82,83) 2 (1)
IGHV9S1 -1 (aa 10) 8   7 -1 (aa 73) 2 (1)
IGHV11S1 -1 (aa 10) 8   7 -2 (aa 73,82) 2 (1)

The proteolytic cleavage site between the leader peptide and the V-REGION is putative and the assignment of amino acid 1 to one or the other region is uncertain.

IMGT note:
(1) Probable CDR3-IMGT length by comparison with Rainbow trout (Oncorhyncus mykiss) germline V-GENEs, but needs to be confirmed with germline sequences.

Created: 05/12/2001
Author: Nathalie Bosc