Only FUNCTIONAL and ORF V-GENEs are shown.
IGIV
genes |
FR1-IMGT 1 to 26 |
CDR1-IMGT 27 to 38 |
FR2-IMGT 39 to 55 |
CDR2-IMGT 56 to 65 |
FR3-IMGT 66 to 104 |
CDR3-IMGT
(germline V-GENE) 105 to 115 |
(25,26) | (4,5,7,9-13) | (17) | (2,3,9,10) | (36-39) | (8-11) | |
IGIV1S1 IGIV1S2 IGIV1S3 IGIV1S4 IGIV1S5 IGIV1S6 IGIV1S7 IGIV1S8 IGIV1S9 |
-1 (aa 10) -1 (aa 7) |
13 (2) 13 (2) 12 11 10 9 9 9 7 |
2 3 3 3 3 3 3 3 3 |
-3 (aa 73,81,82) -1 (aa 73) -3 (aa 73,81,82) -3 (aa 73,81,82) -3 (aa 73,81,82) -1 (aa 73) -1 (aa 73) |
11 (1) 10 (1) 11 (1) 10 (1) 9 (1) 11 (1) 8 (1) 11 (1) 11 (1) |
|
IGIV2S1 IGIV2S2 |
-1 (aa 9) |
4 5 |
9 10 |
-2 (aa 73,81) -2 (aa 73,81) |
9 8 (1) |
IMGT notes:
(1) | Probable CDR3-IMGT length but needs to be confirmed with germline sequences. |
(2) | Insertion of 1 amino acid between position 32 and 33 in CDR1-IMGT (32A). |
Created: 22/04/2003
Author: Nathalie Bosc