Number of germline genes and potential repertoire: Human IGLV at 22q11.2

Print of this table: Pallarès et al., Exp. Clin. Immunogenet., 15, 8-18 (1998)

References:
Williams, S.C., Frippiat, J.-P. et al. J. Mol. Biol., 264, 220-232 (1996). PubMed: 8951372
Kawasaki, K. et al. Genome Res., 7, 250-261 (1997). PubMed: 9074928

SubgroupFunctionalORFPseudogeneTotal
IGLV1 (B)
(C)		51(+1)*(+1)*7
--11
IGLV2 (A)5139
IGLV3 (A)8(+2)*112(+2)*23
IGLV4 (A)
(C)		1--1
2--2
IGLV5 (B)3-4**1-4-5
IGLV6 (C) 1--1
IGLV7 (B) 1(+1)* -1(+1)* 3
IGLV8 (C) 1--1
IGLV9 (B) 1--1
IGLV10 (C) 1-12
IGLV11 (C) -1-1
IGLV(I) (A)
(B)
(C)		--11
--22
--44
IGLV(IV) (C) --55
IGLV(V) (C) --22
IGLV(VI) (A) --22
IGLV(VII) (B) --11
Total29-30(+3)* 5(+1)*35(+4)* 73-74

* FUNCTIONAL or PSEUDOGENE (IGLV3-9, IGLV3-22, IGLV7-46)
* ORF or PSEUDOGENE (IGLV1-41)
** Allelic polymorphism by insertion/deletion: IGLV5-39 [Frippiat et al. Human Molecular Genetics, 4, 983-991 (1995)].
A, B, C (in parentheses) refer to three distinct V-CLUSTERs based on the IGLV gene subgroup content [Williams, Frippiat et al. J. Mol. Biol., 264, 220-232 (1996)].
I, IV, V, VI, VII (in parentheses) refer to the clans for the pseudogenes which cannot be assigned to subgroups with functional genes.

Created: 09/04/1997
Last updated: Wednesday, 12-Jun-2024 16:02:37 CEST
Author: Nathalie Pallarès