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TR rearrangements in human leukemia/lymphoma T cell lines

T cell lines are from [1]. Rearrangements (from [1], unless indicated) are described in this table according to IMGT gene nomenclature.
Allele names are only reported for V and J genes when long sequences are available. TRBD alleles are from IMGT/JunctionAnalysis.
The codon 118 (J-PHE of the 5’J-REGION) has been added in 3’ of the junction sequences, if missing, based on the assignment of the TRBJ, TRGJ and TRDJ genes in the publications, to allow analysis by IMGT/JunctionAnalysis in IMGT/V-QUEST: ttt or ttc for TRBJ or TRDJ, ttt for TRGJ;

T cell malignancy of origin Surface receptors T cell line Alternative clone cell line ATCC® TRB TRG TRD
TRBV - TRBD- TRBJ rearrangements In frame Partial (D-J, V-D) or unusual (D-D, J-J) rearrangements TRGV - TRGJ rearrangements In frame TRDV - TRDD- TRDJ rearrangements In frame Partial (D-J) or deltaRec rearrangements
T ALLCD3-ARR TRBV14 - TRBD2*02 - TRBJ2-7+TRBD1 - TRBJ1-1TRGV4 - TRGJ1 or TRGJ2-TRDV1 - TRDD3*01 - TRDJ1+
TRBD1 - TRBJ1-6TRGV9 - TRGJP1+
CML-T1 TRBV5-8 - TRBJ2-7+TRGV2 - TRGJ1 or TRGJ2+
TRBV10-3 - TRBJ2-7+TRGV4 - TRGJ1 or TRGJ2-
TRBV19 - TRBD2*01 - TRBJ2-5+
DU.528 TRBV28 - TRBD1*01 - TRBJ2-2+TRBD1 - TRBD2TRGV8 - TRGJ1 or TRGJ2-
TRGV2 - TRGJ1 or TRGJ2-
H-SB2 TRBV5-1 - TRBD1*01 - TRBJ1-1+TRGV9 - TRGJ1 or TRGJ2-
TRGV10 - TRGJ1 or TRGJ2-
Karpas 45 TRBV20-1 - TRBD2*01 - TRBJ2-5+TRGV10 - TRGJ1 or TRGJ2+
TRBV5-1 - TRBD2*01 - TRBJ2-1-TRGV8 - TRGJ1 or TRGJ2+
KE-37SKW-3 TRBV3-2 - TRBD1*01 - TRBJ1-5-TRGV8 - TRGJ1 or TRGJ2-
TRGV9 - TRGJ1 or TRGJ2+
MOLT-3 (1)CRL-1552™ TRBV10-3 - TRBD1*01 - TRBJ2-5-TRGV2 - TRGJP1-
MOLT-4 (1)CRL-1582™ TRBV20-1*01 - TRBD2*01 - TRBJ2-1*01 (M12886)+TRGV2 - TRGJP1-
TRBV10-3 - TRBD1*01 - TRBJ2-5-TRGV2 - TRGJP2 (X12620)-
PF-382 TRBV20-1 - TRBD2*01 - TRBJ2-1+TRGV4 - TRGJ1 or TRGJ2-
TRBV7-5 - TRBD1*01 - TRBJ2-7-TRGV10 - TRGJ1 or TRGJ2+
P12-Ichikawa TRBV6-1 - TRBD1*01 - TRBJ2-1+TRGV4 - TRGJ1 or TRGJ2-TRDV1 - TRDD3*01 - TRDJ1-TRBD1 - TRBJ1-5
TRGV9 - TRGJ1 or TRGJ2+
RPMI 8402ALL-1 TRBV19 - TRBD1*01 - TRBJ2-7-TRGV4 - TRGJ1 or TRGJ2+
TRBV15 - TRBD1*01 - TRBJ1-5+TRGV10 - TRGJ1 or TRGJ2-
SUP-T1CRL-1942™ TRBV9*01 - TRBD2*01 - TRBJ2-1*01 (M16834)+TRGV3 - TRGJ1 or TRGJ2+
TRGV4 - TRGJ1 or TRGJ2-
SUP-T3 TRBV28 - TRBD1*01 - TRBJ2-3+TRGV5 - TRGJ1 or TRGJ2-
TRGV8 - TRGJ1 or TRGJ2+
TR-ALPHA_BETACCRF-CEMCCL-119™ TRBV3-1*01 - TRBD1*01 - TRBJ2-3*01 (M13576)+TRBJ1-5 - TRBJ2-1TRGV3 - TRGJ1 or TRGJ2+
TRBV9 - TRBD2 (X02987)TRGV4 - TRGJ1 or TRGJ2+
HPB-ALL TRBV5-5*02 - TRBD2*01 - TRBJ2-5*01 (M14299, M13551)+TRGV3 - TRGJ1 or TRGJ2-
TRBV7-3*05 - TRBD2*02 - TRBJ2-5*01 (M13550, M12883)-TRGV3 - TRGJ1 or TRGJ2-
JurkatE6-1 cloneTIB-152™ TRBV12-3*01 - TRBD1*01 - TRBJ1-2*01 (GU326331, X02515, X01417)+TRBD1 - TRBJ1-3TRGV8 - TRGJ1 or TRGJ2+
TRGV11 - TRGJ1 or TRGJ2-
K-T1 TRBV24-1 - TRBD1*01 - TRBJ1-2-TRGV9 - TRGJ1 or TRGJ2-
TRBV18 - TRBD1*01 - TRBJ2-3+TRGV8 - TRGJ1 or TRGJ2+
MOLT 16MOLT 17 TRBV20-1 - TRBD2*01 - TRBJ2-3+TRGV8 - TRGJP2+
TRBV27 - TRBD1*01 - TRBJ1-1-TRGV8 - TRGJ1 or TRGJ2+
TALL-1 TRBV20-1 - TRBD1*01 - TRBJ2-5+TRGV5 - TRGJ1 or TRGJ2+
TRBV5-6 - TRBD2*01 - TRBJ2-3-TRGV11 - TRGJ1 or TRGJ2-
TALL-104CRL-11386™ TRBV20-1 - TRBD2*01 - TRBJ2-3+TRGV8 - TRGJ1 or TRGJ2-
TRBV24-1 - TRBD1*01 - TRBJ2-2-TRGV10 - TRGJ1 or TRGJ2-
TR-BETA_DELTADND-41 TRBV6-2 - TRBD1*01 - TRBJ2-7-TRGV5 - TRGJ1 or TRGJ2-TRDV1 - TRDD2*01 - TRDJ1+
TRBV18 - TRBD1*01 - TRBJ1-2+TRGV8 - TRGJ1 or TRGJ2-
TR-GAMMA_DELTALoucy [2]CRL-2629™ TRBV20-1 - TRBD1*01 - TRBJ2-2-TRGV2 - TRGJ1 or TRGJ2+TRAV23/DV6 - TRDJ2-TRDD2 - TRDJ1
TRBV5-6 - TRBD1*01 - TRBJ2-1+TRGV9 - TRGJ1 or TRGJ2+
MOLT 13 TRBV10-1 - TRBD1*01 - TRBJ1-1+TRBD1 - TRBJ1-5TRGV3 - TRGJ1 or TRGJ2+TRDV1 - TRDD3*01 - TRDJ1+dREC - TRDJ1
TRBD2 - TRBJ2-3TRGV8 - TRGJP1-
PeerBe13 TRBV4-2 - TRBD2*01 - TRBJ2-3+TRGV8 - TRGJ1 or TRGJ2+TRDV1 - TRDD3*01 - TRDJ1+
TRBV25-1 - TRBD2*01 - TRBJ2-7-TRGV9 - TRGJ1 or TRGJ2-
CTCLHuT 78H9TIB-161™ TRBV13 - TRBD1*01 - TRBJ1-2+TRGV5 - TRGJ1 or TRGJ2+
TRBD2 - TRBJ2-3TRGV8 - TRGJP1-
HuT 102TIB-162™ TRBV30*04 - TRBD2*02 - TRBJ1-2*01 (M13554)+TRBD2 - TRBJ2-1TRGV7 - TRGJ1 or TRGJ2+
TRGV8 - TRGJP1+
ATLLMT-1 TRBV20-1*03 - TRBD2*01 - TRBJ2-3*01 (M11954)+TRGV2 - TRGJ1 or TRGJ2+
TRBVC*01 - TRBD2*02 - TRBJ2-3*01 (M11957)+TRGV10 - TRGJ1 or TRGJ2-
ALCLJB6 TRBV12-4 - TRBD2*01 - TRBJ2-3*01+TRBD1 - TRBJ2-2TRGV2 - TRGJ1 or TRGJ2+
TRGV10 - TRGJ1 or TRGJ2-
Karpas 299 TRBV20-1 - TRBD2*01 - TRBJ2-7+TRBD1 - TRBJ1-6TRGV2 - TRGJP2-
TRGV8 - TRGJ1 or TRGJ2-
SU-DHL-1CRL-2955™ TRBV27 - TRBD1*01 - TRBJ2-3+TRGV4 - TRGJ1 or TRGJ2-
TRGV2 - TRGJ1 or TRGJ2-

TRB V-(D)-J junction sequences

T cell line Alternative clone cell line TRBV - TRBD- TRBJ rearrangements 3'V-REGION P N1 P D-REGION P N2 P 5'J-REGION -3'V (N) -5'D (D) -3'D (N) -5'J
ARRTRBV14 - TRBD2*02 - TRBJ2-7tgtgccagcagcc.... tt ....ctagcgggag.. tcc ..cctacgagcagtacttc-4 (2) -4 (10) -2 (3) -2
CML-T1TRBV5-8 - TRBJ2-7tgtgccagcagct...       ..cctacgagcagtacttc-3 (0) 0 (0) 0 (0) -2
TRBV10-3 - TRBJ2-7tgtgccatcagt.....       ....tacgagcagtacttc-5 (0) 0 (0) 0 (0) -4
TRBV19 - TRBD2*01 - TRBJ2-5tgtgcc........... tccactaccc .ggactagcgggggg.   ..caagagacccagtacttc-11 (10) -1 (14) -1 (0) -2
DU.528TRBV28 - TRBD1*01 - TRBJ2-2tgtgccagcagtt.... cac ..gacagggggcgctttttaa .gaacaccggggagctgtttttt-4 (3) -2 (10) 0 (9) -1
H-SB2TRBV5-1 - TRBD1*01 - TRBJ1-1tgcgccagcagct...   .ggacaggg... tatgg .gaacactgaagctttcttt-3 (0) -1 (8) -3 (5) -1
Karpas 45TRBV20-1 - TRBD2*01 - TRBJ2-5tgcagtgctag... tggtt ....ctagcgg..... agccagca ...aagagacccagtacttc-3 (5) -4 (7) -5 (8) -3
TRBV5-1 - TRBD2*01 - TRBJ2-1tgcgccag........ tatctcagcaggta ...actag........ gac ......caatgagcagttcttc-8 (14) -3 (5) -8 (3) -6
KE-37SKW-3TRBV3-2 - TRBD1*01 - TRBJ1-5tgtgccagcagccaaga ctccgggacagggg.. cggg tagcaatcagccccagcatttt0 (4) 0 (10) -2 (4) 0
MOLT-3TRBV10-3 - TRBD1*01 - TRBJ2-5tgtgccatcagtgag.. cc ..gacaggg... atcag ...aagagacccagtacttc-2 (2) -2 (7) -3 (5) -3
MOLT-4TRBV20-1*01 - TRBD2*01 - TRBJ2-1*01 (2)tgcagtgctagaga gtc ..gactagcg...... atccaaaa .......aatgagcagttcttc0 (3) -2 (8) -6 (8) -7
TRBV10-3 - TRBD1*01 - TRBJ2-5tgtgccatcagtgag.. cc ..gacaggg... atcag ...aagagacccagtacttc-2 (2) -2 (7) -3 (5) -3
PF-382TRBV20-1 - TRBD2*01 - TRBJ2-1tgcagtgc...... cacgtcgggactagcggg.... ctta .......aatgagcagttcttc-6 (6) 0 (12) -4 (4) -7
TRBV7-5 - TRBD1*01 - TRBJ2-7tgtgccagaagct... cagaggcttt ....caggg... cgag ......cgagcagtacttc-3 (10) -4 (5) -3 (4) -6
P12-IchikawaTRBV6-1 - TRBD1*01 - TRBJ2-1tgtgccagcagt..... atcc .ggac....... gcctcaccctca ...ctacaatgagcagttcttc-5 (4) -1 (4) -7 (12) -3
RPMI 8402ALL-1TRBV19 - TRBD1*01 - TRBJ2-7tgtgcc........... tat ....cagggg.. agagtgggct ctcctacgagcagtacttc-11 (3) -4 (6) -2 (10) 0
TRBV15 - TRBD1*01 - TRBJ1-5tgtgccaccagcagagatggaa .....aggg... c .agcaatcagccccagcatttt0 (5) -5 (4) -3 (1) -1
SUP-T1TRBV9*01 - TRBD2*01 - TRBJ2-1*01tgtgccagcagcgtag gtgg .....tagc....... ttgaaa .............cagttcttc0 (4) -5 (4) -7 (6) -13
SUP-T3TRBV28 - TRBD1*01 - TRBJ2-3tgtgccagcagttta..   .ggacagg.... ccctc agcacagatacgcagtatttt-2 (0) -1 (7) -4 (5) 0
CCRF-CEMTRBV3-1*01 - TRBD1*01 - TRBJ2-3*01tgtgccagcagcc.... tt ggg.........   ...acagatacgcagtatttt-4 (2) 0 (3) -9 (0) -3
HPB-ALLTRBV5-5*02 - TRBD2*01 - TRBJ2-5*01tgtgccagcagct... c .......gcgg..... aaa ........acccagtacttc-3 (1) -7 (4) -5 (3) -8
TRBV7-3*05 - TRBD2*02 - TRBJ2-5*01tgtgccagcagc..... ccaa .........gggagg.   .....gagacccagtacttc-5 (4) -9 (6) -1 (0) -5
JurkatE6-1 cloneTRBV12-3*01 - TRBD1*01 - TRBJ1-2*01tgtgccagcagttt... ctc ..gac....... ctgttcggctaactatggctacaccttc-3 (3) -2 (3) -7 (8) 0
K-T1TRBV24-1 - TRBD1*01 - TRBJ1-2tgtgccac.......... gccccccc ..gacag..... tttg .taactatggctacaccttc-10 (8) -2 (5) -5 (4) -1
TRBV18 - TRBD1*01 - TRBJ2-3tgtgccagctcacc... ga ..gacagg.... cgacgg ....cagatacgcagtatttt-3 (2) -2 (6) -4 (6) -4
MOLT 16MOLT 17TRBV20-1 - TRBD2*01 - TRBJ2-3tgcagtgc...... aggggagt ........cgggggg. cgta ...acagatacgcagtatttt-6 (8) -8 (7) -1 (4) -3
TRBV27 - TRBD1*01 - TRBJ1-1tgtgccagca....... ccgaccc .ggacagggg.. aatgg .....actgaagctttcttt-7 (7) -1 (9) -2 (5) -5
TALL-1TRBV20-1 - TRBD1*01 - TRBJ2-5tgcagtg....... accc ....cag..... cag ....agagacccagtacttc-7 (4) -4 (3) -5 (3) -4
TRBV5-6 - TRBD2*01 - TRBJ2-3tgtgccagcagc.... g gggactagcggg.... tgagg ......gatacgcagtatttt-4 (1) 0 (12) -4 (5) -6
TALL-104TRBV20-1 - TRBD2*01 - TRBJ2-3tgcagtgcta.... agctta .........ggggggg gcgcc ....cagatacgcagtatttt-4 (6) -9 (7) 0 (5) -4
TRBV24-1 - TRBD1*01 - TRBJ2-2tgtgccaccagtgat... ct gggacaggg... a .....accggggagctgtttttt-3 (2) 0 (9) -3 (1) -5
DND-41TRBV6-2 - TRBD1*01 - TRBJ2-7tgtgccagcagttac.. cccc ..gacaggg... aggagaggggctcctacgagcagtacttc-2 (4) -2 (7) -3 (10) 0
TRBV18 - TRBD1*01 - TRBJ1-2tgtgccagctcacc...  cgggacaggg... aga .....tatggctacaccttc-3 (1) 0 (9) -3 (3) -5
LoucyTRBV20-1 - TRBD1*01 - TRBJ2-2tgcagtgctagag. cagaggcg ....cagg....   .gaacaccggggagctgtttttt-1 (8) -4 (4) -4 (0) -1
TRBV5-6 - TRBD1*01 - TRBJ2-1tgtgccagcagc.... cg .....agggg.. aacccccctgga ..cctacaatgagcagttcttc-4 (2) -5 (5) -2 (12) -2
MOLT 13TRBV10-1 - TRBD1*01 - TRBJ1-1tgcgccagcag...... gagagttagacgggacag.....   .gaacactgaagctttcttt-6 (11) 0 (7) -5 (0) -1
PeerBe13TRBV4-2 - TRBD2*01 - TRBJ2-3tgtgccagcagccaaga   ..gact.......... ctaccactccgcctggg ........tacgcagtatttt0 (0) -2 (4) -10 (17) -8
TRBV25-1 - TRBD2*01 - TRBJ2-7tgtgccagca....... cggt ..........ggag.. cagtaccc ..cctacgagcagtacttc-7 (4) -10 (4) -2 (8) -2
HuT 78H9TRBV13 - TRBD1*01 - TRBJ1-2tgtgccagcagc..... accagcc ....cagggggc cgg ........ggctacaccttc-5 (7) -4 (8) 0 (3) -8
HuT 102TRBV30*04 - TRBD2*02 - TRBJ1-2*01tgtgcctggagt.. aggca ..........ggagg. cggttggc ........ggctacaccttc-2 (5) -10 (5) -1 (8) -8
MT-1TRBV20-1*03 - TRBD2*01 - TRBJ2-3*01tgcagtgcta.... a ...actag........ taggt ...acagatacgcagtatttt-4 (1) -3 (5) -8 (5) -3
TRBVC*01 - TRBD2*02 - TRBJ2-3*01tgcaccagcagt..... ccat .ggactagcggga... tt ...acagatacgcagtatttt-5 (4) -1 (12) -3 (2) -3
JB6TRBV12-4 - TRBD2*01 - TRBJ2-3*01tgtgccagcag......   ...actagcgggggg. ac ....cagatacgcagtatttt-6 (0) -3 (12) -1 (2) -4
Karpas 299TRBV20-1 - TRBD2*01 - TRBJ2-7tgcagtgctagag. cccagatagggt ....ctagc....... cccct ......cgagcagtacttc-1 (12) -4 (5) -7 (5) -6
SU-DHL-1TRBV27 - TRBD1*01 - TRBJ2-3tgtgccagcagttt... cagt .....agggg.. a ...acagatacgcagtatttt-3 (4) -5 (5) -2 (1) -3

TRG V-(D)-J junction sequences

T cell line Alternative clone cell line TRGV - TRGJ rearrangements 3'V-REGION P N P 5'J-REGION -3'V (N) -5'J
ARRTRGV9 - TRGJP1tgtgccacctggga....  .............................gaacaacactt-4 (0) -29
TRGV4 - TRGJ1 or TRGJ2tgtgccttgtggga.... ctttaaattgggttca .....actggttggttcaagatattt-4 (16) -5
CML-T1TRGV2 - TRGJ1 or TRGJ2tgtgccacctggga.... gggcccca .......................gcagtggaacaacactg-4 (8) -23
TRGV4 - TRGJ1 or TRGJ2tgtgccacctgggatggg accaggag ..attattataagaaactcttt0 (8) -2
DU.528TRGV8 - TRGJ1 or TRGJ2tgtgcca........... aa .....attataagaaactcttt-11 (2) -5
TRGV2 - TRGJ1 or TRGJ2tgtgccacctgggacgg. cccctctcgaattattataagaaactcttt-1 (8) 0
H-SB2TRGV9 - TRGJ1 or TRGJ2tgtgccttgtgggaggtg   ..attattataagaaactcttt0 (0) -2
TRGV10 - TRGJ1 or TRGJ2tgtgctgcgtgg........ gattatcag ...ttattataagaaactcttt-8 (9) -3
Karpas 45TRGV10 - TRGJ1 or TRGJ2tgtgctgcgtgg........ gta .aattattataagaaactcttt-8 (3) -1
TRGV8 - TRGJ1 or TRGJ2tgtgccacctgg...... tc .........taagaaactcttt-6 (4) -11
KE-37SKW-3TRGV8 - TRGJ1 or TRGJ2tgtgccacctggga.... ccgtccgccatcccgt ..attattataagaaactcttt-4 (16) -2
TRGV9 - TRGJ1 or TRGJ2tgtgccttgtgggaggtgc cgaattattataagaaactcttt0 (2) 0
MOLT-3TRGV2 - TRGJP1tgtgccacct........ tcg ...................gatattt-8 (3) -19
MOLT-4TRGV2 - TRGJP1tgtgccacct........ tcg ...................gatattt-8 (3) -19
TRGV2 - TRGJP2tgtgccacctggga.... ggggggtgtct .......tgattggatcaagacgttt-4 (11) -7
PF-382TRGV4 - TRGJ1 or TRGJ2tgtgccacctggga....  .............................gaacaacactt-4 (0) -29
TRGV10 - TRGJ1 or TRGJ2tgtgctgcgtgg........ gatgagggc .......tataagaaactcttt-8 (9) -7
P12-IchikawaTRGV4 - TRGJ1 or TRGJ2tgtgccacctggg..... ttaaaattcccct .aattattataagaaactcttt-5 (13) -1
TRGV9 - TRGJ1 or TRGJ2tgtgccttgtgggaggt. ctccgctt ...........agaaactcttt-1 (8) -11
RPMI 8402ALL-1TRGV4 - TRGJ1 or TRGJ2tgtgccacctgggatgg. agcgtctacgaattattataagaaactcttt-1 (9) 0
TRGV10 - TRGJ1 or TRGJ2tgtgctgcgtgg........ ggt ..attattataagaaactcttt-8 (3) -2
SUP-T1TRGV3 - TRGJ1 or TRGJ2tgtgccacctgg...... cggacgaattattataagaaactcttt-6 (5) 0
TRGV4 - TRGJ1 or TRGJ2tgtgccacctgggatgggcaata .aattattataagaaactcttt0 (5) -1
SUP-T3TRGV5 - TRGJ1 or TRGJ2tgtgccacctgggacaggccggtgcagg ............gaaactcttt0 (10) -12
TRGV8 - TRGJ1 or TRGJ2tgtgccacctggg..... tc ..........aagaaactcttt-5 (2) -10
CCRF-CEMTRGV3 - TRGJ1 or TRGJ2tgtgccacctgggacag. ttccc ........ataagaaactcttt-1 (5) -8
TRGV4 - TRGJ1 or TRGJ2tgtgccacctgggat... taaggggggttg ......................ggcagtggaacaacactt-3 (12) -22
HPB-ALLTRGV3 - TRGJ1 or TRGJ2tgtgccacctgggacaggcaaa .aattattataagaaactcttt0 (4) -1
TRGV3 - TRGJ1 or TRGJ2tgtgccacctggga.... taaacgctgcctttctgacgggggt ......ttataagaaactcttt-4 (25) -6
JurkatE6-1 cloneTRGV8 - TRGJ1 or TRGJ2tgtgccacctgg...... aaatt ...ttattataagaaactcttt-6 (5) -3
TRGV11 - TRGJ1 or TRGJ2tgtgcctg............. tcagatcctcacagggcgggtt .........taagaaactcttt-13 (22) -9
K-T1TRGV9 - TRGJ1 or TRGJ2tgtgcctt.......... ccggcccg ..........aagaaactcttt-10 (8) -10
TRGV8 - TRGJ1 or TRGJ2tgtgccacctgg...... tc .........taagaaactcttt-6 (2) -9
MOLT 16MOLT 17TRGV8 - TRGJP2tgtgcc............ cccctggagg ...........tggatcaagacgttt-12 (10) -11
TRGV8 - TRGJ1 or TRGJ2tgtgccacctgg...... acagataggatc ....tattataagaaactcttt-6 (12) -4
TALL-1TRGV5 - TRGJ1 or TRGJ2tgtgccacctgg......  tcgaattattataagaaactcttt-6 (2) 0
TRGV11 - TRGJ1 or TRGJ2tgtgcctgctggattaggcac cc .aattattataagaaactcttt0 (2) -1
TALL-104TRGV8 - TRGJ1 or TRGJ2tgtgccacctgggat... ctgg ...ttattataagaaactcttt-3 (4) -3
TRGV10 - TRGJ1 or TRGJ2tgtgctgcgtgg........ gaccgcac .......tataagaaactcttt-8 (8) -7
DND-41TRGV5 - TRGJ1 or TRGJ2tgtgccacc......... ggccacctt ...ttattataagaaactcttt-9 (9) -3
TRGV8 - TRGJ1 or TRGJ2tgtgccacctggga.... cacataaggggg ...............................acaacactt-4 (12) -31
LoucyTRGV2 - TRGJ1 or TRGJ2tgtgccacctggg..... gttcccaggatttcac ..................cttt-5 (16) -18
TRGV9 - TRGJ1 or TRGJ2tgtgccttgtgggag... ccccccccctcgaattattataagaaactcttt-3 (11) 0
MOLT 13TRGV3 - TRGJ1 or TRGJ2tgtgccacctgggacaggccccgcct .........taagaaactcttt0 (8) -9
TRGV8 - TRGJP1tgtgccacctgggat...   ...ccactggttggttcaagatattt-3 (0) -3
PeerBe13TRGV8 - TRGJ1 or TRGJ2tgtgccacctgg...... aagg ..attattataagaaactcttt-6 (4) -2
TRGV9 - TRGJ1 or TRGJ2tgtgcctt.......... ccggcccg ..........aagaaactcttt-10 (8) -10
HuT 78H9TRGV5 - TRGJ1 or TRGJ2tgtgccacctgggacaggcttacct ..attattataagaaactcttt0 (7) -2
TRGV8 - TRGJP1tgtgccacctgg...... acacctt ....cactggttggttcaagatattt-6 (7) -4
HuT 102TRGV7 - TRGJ1 or TRGJ2tgtgccacctgggac... gcggctg ........ataagaaactcttt-3 (7) -8
TRGV8 - TRGJP1tgtgccacctgggat... gagc ...ccactggttggttcaagatattt-3 (4) -3
MT-1TRGV2 - TRGJ1 or TRGJ2tgtgccacctgggacgggcc  ......ttataagaaactcttt0 (2) -6
TRGV10 - TRGJ1 or TRGJ2tgtgctgcgtgg........ gat ...ttattataagaaactcttt-8 (3) -3
JB6TRGV2 - TRGJ1 or TRGJ2tgtgccacctggg..... gatccatataggt gaattattataagaaactcttt-5 (13) 0
TRGV10 - TRGJ1 or TRGJ2tgtgctgcgtggt....... cttgaggctggc ............gaaactcttt-7 (12) -12
Karpas 299TRGV2 - TRGJP2tgtgccacctgggacggg ggttaagttcctt ....tagtgattggatcaagacgttt0 (13) -4
TRGV8 - TRGJ1 or TRGJ2tgtgccacctgggataggcc  .....attataagaaactcttt0 (2) -5
SU-DHL-1TRGV4 - TRGJ1 or TRGJ2tgtgccacct........ ctcccaaaacccccaag ..attattataagaaactcttt-8 (17) -2
TRGV2 - TRGJ1 or TRGJ2tgtgccacctggg..... c ..........aagaaactcttt-5 (1) -10

TRD V-(D)-J junction sequences

T cell line Alternative clone cell line TRDV - TRDD- TRDJ rearrangements 3'V-REGION P N1 P D-REGION N2 P 5'J-REGION -3'V (N) -5'D (D) -3'D (N) -5'J
ARRTRDV1 - TRDD3*01 - TRDJ1tgtgctctt........ cgggaacg ...gggggat...ttctacctgtttgggtcgggggaagcgtacacggac ........aaactcatcttt-8 (8) -3 (7) -3 (36) -8
P12-IchikawaTRDV1 - TRDD3*01 - TRDJ1tgtgctcttggggaactacgacctctactgg........tcgaag .caccgataaactcatcttt0 (9) 0 (5) -8 (6) -1
DND-41TRDV1 - TRDD2*01 - TRDJ1tgtgctcttggggaa..  gccttcc...gaccatcacgcacctt .caccgataaactcatcttt-2 (1) 0 (6) -3 (16) -1
LoucyTRAV23/DV6 - TRDJ2tgtgcagcaagca aagctgccgg    .tttgacagcacaactcttcttt-1 (12) 0 (0) 0 (0) -1
MOLT 13TRDV1 - TRDD3*01 - TRDJ1tgtgctcttggggaac.   .ctggggg..... gtacaccgataaactcatcttt-1 (0) -1 (7) -5 (2) 0
PeerBe13TRDV1 - TRDD3*01 - TRDJ1tgtgctcttggg..... ac ...ggggg.....tgaggggactccagg acaccgataaactcatcttt-5 (2) -3 (5) -5 (15) 0
Abbreviations:
ALCL: anaplastic large cell lymphoma
ATLL: adult T-cell lymphoma leukemia
CTCL: cutaneous T cell lymphoma
(D): number of nucleotides of D-REGION
(N): number of N and/or P nucleotides
-3'D: number of trimmed nucleotides at the 3' end of D-REGION
-3'V: number of trimmed nucleotides at the 3' end of V-REGION
-5'D: number of trimmed nucleotides at the 5' end of D-REGION
-5'J: number of trimmed nucleotides at the 5' end of J-REGION
IMGT notes:
(1) MOLT-3 and MOLT-4 were derived from the same patient. MOLT-3 is CD3-. MOLT-4 expressed CD3 A (26%), CD3 B (33%) and CD3 C (34%).
(2) In [1], one nucleotide 'a' is missing in codon 118 which should be 'gag'.
References:
[1] Sandberg Y. et al., Leukemia, 21, 230-237 (2007). PMID: 17170727
[2] Ben-Bassat H. et al., Cancer Genet Cytogenet, 49, 241-248 (1990). PMID: 2208060