IMGT Web resources: IMGT repertoire

Alignment of alleles: Gorilla (Gorilla gorilla) IGHG1

When several alleles are shown, the nucleotide mutations and amino acid changes for a given codon are indicated in red letters.
Dashes indicate identical nucleotides. Dots indicate gaps by comparison to the longest sequence. Blanks indicate partial sequences (blanks at the 5' and/or 3' end).

The nucleotide between parentheses at the beginning of exons comes from a DONOR-SPLICE (n from ngt). The first nucleotide from an INT-DONOR-SPLICE is underlined (n from ngt).

Exon names are shown between parentheses on the first line.
The Cysteines involved in the IG CH1, CH2 and CH3 intrachain disulfide bridge are shown with a larger letter C in purple. The Cysteines involved in the H-L or H-H interchain disulfide bridge are shown with a larger letter C in black.
STOP-CODON is indicated by an asterisk.

N (Asn, asparagine) of potential N-glycosylation sites (NXS/T, where X is different from P), (N-linked glycosylation) is shown is green (site is underlined in CHS and in pages edited before 14/10/2009).

                                                    1.4 1.3 1.2 1.1   1   2   3   4   5   6   7   8   9  10  11

  AF300449,IGHG1*01 (CH1)

                                                ___AB_______                                            ________
                                               15.1    15.3                                                    
                                 12  13  14  15    15.2      16  17  18  19  20  21  22  23  24  25  26  27  28

  AF300449,IGHG1*01 (CH1)

                                _________BC_____________________                            ___________CD_______
                                                                                           45.1    45.3    45.5
                                 29  30  31  32  33  34  35  36  39  40  41  42  43  44  45    45.2    45.4    

  AF300449,IGHG1*01 (CH1)

                                ________                                _________________________DE_____________
                                   45.7                                84.1    84.3    84.5    84.7    85.6    
                               45.6      77  78  79  80  81  82  83  84    84.2    84.4    84.6    85.7    85.5
                                                                 A   V   L   Q   S   S
  AF300449,IGHG1*01 (CH1)                                       GCT GTC CTA CAG TCC TCA ... ... ... ... ... ...

                                ________________                                                _EF_____
                               85.4    85.2                                                    96.1    
                                   85.3    85.1  85  86  87  88  89  90  91  92  93  94  95  96    96.2  97  98
                                 G   L   Y   S   L   S   S   V   V   T   V   P   S   S   S   L               G
  AF300449,IGHG1*01 (CH1)       GGA CTC TAC TCC CTC AGC AGC GTG GTG ACC GTG CCC TCC AGC AGC TTG ... ... ... GGC

                                                        _______________________FG___________________________
                                                                                                           
                                 99 100 101 102 103 104 105 106 107 108 109 110 111 112 113 114 115 116 117 118
                                 T   Q   T   Y   I   C   N   V   N   H   K   P           S   N   T   K   V   D
  AF300449,IGHG1*01 (CH1)       ACC CAG ACC TAC ATC TGC AAC GTA AAT CAC AAG CCC ... ... AGC AAC ACG AAG GTG GAC


                                119 120 121
                                 K   K   V
  AF300449,IGHG1*01 (CH1)       AAG AAA GTT G



                                  1   2   3   4   5   6   7   8   9  10  11  12  13  14  15
                                 E   P   K   S   C   D   T   T   H   T   C   P   P   C   A
  AF300449,IGHG1*01 (H)          AG CCC AAA TCT TGT GAC ACA ACT CAC ACA TGC CCA CCG TGC GCA G




                                            1.6 1.5 1.4 1.3 1.2 1.1   1   2   3   4   5   6   7   8   9  10  11
                                             A   P   E   L   L   G   G   P   S   V   F   L   F   P   P   K   P
  AF300449,IGHG1*01 (CH2)                    CA CCT GAA CTC CTG GGG GGA CCG TCA GTC TTC CTC TTC CCC CCA AAA CCC

                                                ___AB_______
                                               15.1    15.3
                                 12  13  14  15    15.2      16  17  18  19  20  21  22  23
                                 K   D   T   L   M   I       S   R   T   P   E   V   T   C  
  AF300449,IGHG1*01 (CH2)       AAG GAC ACC CTC ATG ATC ... TCC CGG ACC CCT GAG GTC ACA TGC G

This alignment has been generated with the IMGT/AlleleAlign tool developed by Mehdi Yousfi (31/07/2001)

Created: 12/11/2002
Author: Nathalie Bosc