When several alleles are shown, the nucleotide mutations and amino acid changes for a given codon are indicated
in red letters.
Dashes indicate identical nucleotides. Dots indicate gaps by comparison to the longest
sequence. Blanks indicate partial sequences (blanks at the 5' and/or 3' end).
The nucleotide between parentheses at the beginning of exons comes from a DONOR-SPLICE (n from ngt). The first nucleotide from an INT-DONOR-SPLICE is underlined (n from ngt).
Exon names are shown between parentheses on the first line.
The Cysteines involved in the IG CH1, CH2 and CH3 intrachain disulfide bridge are shown with a larger letter C in purple.
The Cysteines involved in the H-L or H-H interchain disulfide bridge are shown with a larger letter C in black.
STOP-CODON is indicated by an asterisk.
N (Asn, asparagine) of potential N-glycosylation sites (NXS/T, where X is different from P), (N-linked glycosylation) is shown is green (site is underlined in CHS and in pages edited before 14/10/2009).
1.4 1.3 1.2 1.1 1 2 3 4 5 6 7 8 9 10 11
AF300445,IGHGP*01 (CH1)
___AB_______ ________
15.1 15.3
12 13 14 15 15.2 16 17 18 19 20 21 22 23 24 25 26 27 28
AF300445,IGHGP*01 (CH1)
_________BC_____________________ ___________CD_______
45.1 45.3 45.5
29 30 31 32 33 34 35 36 39 40 41 42 43 44 45 45.2 45.4
AF300445,IGHGP*01 (CH1)
________ _________________________DE_____________
45.7 84.1 84.3 84.5 84.7 85.6
45.6 77 78 79 80 81 82 83 84 84.2 84.4 84.6 85.7 85.5
A V L Q S S
AF300445,IGHGP*01 (CH1) GCT GTC CTA CAG TCC TCA ... ... ... ... ... ...
________________ _EF_____
85.4 85.2 96.1
85.3 85.1 85 86 87 88 89 90 91 92 93 94 95 96 96.2 97 98
G L Y S L S S V V T V P S S S L G
AF300445,IGHGP*01 (CH1) GGA CTC TAC TCC CTC AGC AGC GTG GTG ACC GTG CCC TCC AGC AGC TTG ... ... ... GGC
_______________________FG___________________________
99 100 101 102 103 104 105 106 107 108 109 110 111 112 113 114 115 116 117 118
T Q T Y T C N V D H K P S N T K V D
AF300445,IGHGP*01 (CH1) ACC CAG ACC TAC ACC TGC AAC GTA GAT CAC AAG CCC ... ... AGC AAC ACC AAG GTG GAC
119 120 121
K R V
AF300445,IGHGP*01 (CH1) AAG AGA GTT G
1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17
E P K T P C C D T T H T W P P C A
AF300445,IGHGP*01 (H) AG CCC AAA ACC CCA TGT TGT GAC ACA ACT CAC ACA TGG CCA CCG TGC GCA G
1.6 1.5 1.4 1.3 1.2 1.1 1 2 3 4 5 6 7 8 9 10 11
A T E P L G G P S V F V F P P K P
AF300445,IGHGP*01 (CH2) CA ACT GAA CCC CTG GGA GGA CCG TCA GTC TTC GTC TTC CCC CCA AAA CCC
___AB_______
15.1 15.3
12 13 14 15 15.2 16 17 18 19 20 21 22 23
K D T L M I S R T P E V T C
AF300445,IGHGP*01 (CH2) AAG GAT ACC CTC ATG ATC ... TCC CGG ACC CCT GAG GTC ACA TGC G
Created: 12/11/2002
Author: Nathalie Bosc