When several alleles are shown, the nucleotide mutations and amino acid
changes for a given codon are indicated in red letters. These polymorphic mutations are reported in
Tables of alleles.
Dashes indicate identical nucleotides. Dots indicate gaps according to the
IMGT unique numbering.
Blanks indicate partial sequences (blanks at the 5' and/or 3' end).
1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20
T L Q E S G P G T V K P S E S L R
M24674 ,IGHV2S1*01 ACA TTG CAA GAG TCT GGT CCT ... GGA ACT GTG AAA CCC TCA GAG TCA CTC AGA
_________________CDR1-IMGT______________________
21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40
L T C T V S G F E I T N Y G L S
M24674 ,IGHV2S1*01 CTG ACC TGC ACA GTT TCT GGG TTT GAG ATA ACT AAC TAT GGT ... ... ... ... TTG AGC
_____________CDR2-IM
41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60
W I R Q P P G K G L E W I G T I V T G G
M24674 ,IGHV2S1*01 TGG ATC AGG CAG CCT CCT GGG AAG GGA CTG GAA TGG ATT GGA ACT ATA GTA ACT GGT GGG
GT__________________
61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79 80
N T Y I A D I L K N R V T I T K
M24674 ,IGHV2S1*01 AAC ACA ... ... ... TAT ATT GCT GAT ATA CTT AAA ... AAC AGA GTT ACA ATT ACT AAA
81 82 83 84 85 86 87 88 89 90 91 92 93 94 95 96 97 98 99 100
D N G K K Q V Y L Q M T A M E V K D T A
M24674 ,IGHV2S1*01 GAC AAT GGG AAG AAG CAG GTC TAT CTC CAA ATG ACT GCA ATG GAA GTT AAA GAC ACT GCC
CDR3-IMGT__
101 102 103 104 105 106
M Y Y C G R
M24674 ,IGHV2S1*01 ATG TAT TAC TGT GGA AGA #c
#c : rearranged cDNA
This alignment has been generated with the IMGT/AlleleAlign tool developed by Mehdi Yousfi (31/07/2001)
Created: 06/08/2003
Author: Delphine Guiraudou