Alignment of alleles: African clawed frog (Xenopus laevis) IGHV2S4

When several alleles are shown, the nucleotide mutations and amino acid changes for a given codon are indicated in red letters. These polymorphic mutations are reported in Tables of alleles.
Dashes indicate identical nucleotides. Dots indicate gaps according to the IMGT unique numbering. Blanks indicate partial sequences (blanks at the 5' and/or 3' end).

                                  1   2   3   4   5   6   7   8   9  10  11  12  13  14  15  16  17  18  19  20
                                     Q   T   L   Q   E   S   G   P       R   T   V   K   P   S   E   S   L   R
  M30028  ,IGHV2S4*01               CAG ACA TTA CAA GAG TCT GGT CCT ... AGA ACT GTG AAA CCC TCA GAG TCA CTC AGA

                                                        _________________CDR1-IMGT______________________
                                 21  22  23  24  25  26  27  28  29  30  31  32  33  34  35  36  37  38  39  40
                                 L   T   C   T   V   S   G   F   E   L   T   R   Y   A                   V   N
  M30028  ,IGHV2S4*01           TTG ACC TGC ACA GTT TCT GGG TTT GAA CTA ACT AGA TAT GCT ... ... ... ... GTA AAC

                                                                                            _____________CDR2-IM
                                 41  42  43  44  45  46  47  48  49  50  51  52  53  54  55  56  57  58  59  60
                                 W   M   R   Q   P   P   G   K   G   P   E   W   I   G   E   V   Y   G   S   G
  M30028  ,IGHV2S4*01           TGG ATG AGG CAG CCT CCT GGG AAG GGA CCG GAA TGG ATT GGA GAA GTA TAC GGT AGT GGG

                                GT__________________
                                 61  62  63  64  65  66  67  68  69  70  71  72  73  74  75  76  77  78  79  80
                                 G   T               A   F   A   D   S   L   K       N   R   V   T   I   T   K
  M30028  ,IGHV2S4*01           GGT ACA ... ... ... GCT TTT GCT GAT TCA CTT AAA ... AAC AGA GTT ACA ATT ACT AAA

                                 81  82  83  84  85  86  87  88  89  90  91  92  93  94  95  96  97  98  99 100
                                 D   N   G   K   K   Q   V   Y   L   Q   M   T   G   M   E   V   K   D   T   A
  M30028  ,IGHV2S4*01           GAC AAT GGG AAG AAG CAG GTC TAC CTC CAA ATG ACT GGG ATG GAA GTT AAA GAC ACT GCC

                                                CDR3-IMGT__
                                101 102 103 104 105 106
                                 M   Y   Y   C   A   D
  M30028  ,IGHV2S4*01           ATG TAT TAC TGT GCA GAC #c
#c : rearranged cDNA

This alignment has been generated with the IMGT/AlleleAlign tool developed by Mehdi Yousfi (31/07/2001)

Created: 06/08/2003
Author: Delphine Guiraudou