Alignment of alleles: African clawed frog (Xenopus laevis) IGHV4S1

When several alleles are shown, the nucleotide mutations and amino acid changes for a given codon are indicated in red letters. These polymorphic mutations are reported in Tables of alleles.
Dashes indicate identical nucleotides. Dots indicate gaps according to the IMGT unique numbering. Blanks indicate partial sequences (blanks at the 5' and/or 3' end).

                                  1   2   3   4   5   6   7   8   9  10  11  12  13  14  15  16  17  18  19  20
                                         L   L   S   Q   K   A   S       E   I   A   N   V   G   T   S   I   L
  M24676  ,IGHV4S1*01                   CTT TTA AGT CAG AAG GCT TCA ... GAA ATA GCA AAT GTT GGG ACA TCC ATA CTG

                                                        _________________CDR1-IMGT______________________
                                 21  22  23  24  25  26  27  28  29  30  31  32  33  34  35  36  37  38  39  40
                                 L   Q   C   E   V   S   G   Y   N   I   N   D   H   H                   M   H
  M24676  ,IGHV4S1*01           TTA CAA TGT GAA GTC AGT GGA TAT AAT ATT AAT GAT CAC CAC ... ... ... ... ATG CAC

                                                                                            _____________CDR2-IM
                                 41  42  43  44  45  46  47  48  49  50  51  52  53  54  55  56  57  58  59  60
                                 W   V   R   Q   A   P   G   P   G   T   I   E   W   L   A   A   Y   R   S   D
  M24676  ,IGHV4S1*01           TGG GTA CGT CAG GCT CCT GGA CCT GGA ACA ATT GAA TGG TTA GCA GCT TAC AGA TCT GAT

                                GT__________________
                                 61  62  63  64  65  66  67  68  69  70  71  72  73  74  75  76  77  78  79  80
                                 T   T               Y   I   S   E   S   F   K       E   R   V   T   P   S   T
  M24676  ,IGHV4S1*01           ACA ACT ... ... ... TAC ATC TCA GAA AGT TTT AAG ... GAG AGG GTA ACT CCA TCC ACA

                                 81  82  83  84  85  86  87  88  89  90  91  92  93  94  95  96  97  98  99 100
                                         S   G   S   T   A   Q   L   R   I   S   K   L   S   R   S   D   T   A
  M24676  ,IGHV4S1*01           ... ... AGT GGC TCC ACT GCA CAA CTA AGG ATT AGC AAG TTA TCA AGG TCA GAC ACT GCT

                                                CDR3-IMGT__
                                101 102 103 104 105 106
                                 T   Y   Y   C   A   T
  M24676  ,IGHV4S1*01           ACA TAT TAT TGT GCA ACG #c
#c : rearranged cDNA

This alignment has been generated with the IMGT/AlleleAlign tool developed by Mehdi Yousfi (31/07/2001)

Created: 06/08/2003
Author: Delphine Guiraudou