Alignment of alleles: African clawed frog (Xenopus laevis) IGHV8S1

When several alleles are shown, the nucleotide mutations and amino acid changes for a given codon are indicated in red letters. These polymorphic mutations are reported in Tables of alleles.
Dashes indicate identical nucleotides. Dots indicate gaps according to the IMGT unique numbering. Blanks indicate partial sequences (blanks at the 5' and/or 3' end).

N (Asn, asparagine) of potential N-glycosylation sites (NXS/T, where X is different from P), (N-linked glycosylation) is shown is green (site is underlined in CHS and in pages edited before 14/10/2009).

                                  1   2   3   4   5   6   7   8   9  10  11  12  13  14  15  16  17  18  19  20
                                 Q   I   T   L   D   Q   P   G   S       A   V   V   N   P   S   G   T   L   K
  M24680  ,IGHV8S1*01           CAG ATT ACT TTA GAC CAA CCT GGC TCT ... GCC GTT GTG AAT CCA TCA GGA ACA TTA AAA

                                                        _________________CDR1-IMGT______________________
                                 21  22  23  24  25  26  27  28  29  30  31  32  33  34  35  36  37  38  39  40
                                 L   S   C   K   V   S   V   S   V   T   S   Q   H                       W   A
  M24680  ,IGHV8S1*01           CTT TCC TGT AAA GTC TCA GTC TCT GTA ACT AGT CAG CAC ... ... ... ... ... TGG GCA

                                                                                            _____________CDR2-IM
                                 41  42  43  44  45  46  47  48  49  50  51  52  53  54  55  56  57  58  59  60
                                 W   T   W   Q   A   P   G   K   G   L   E   Y   I   G   Y   L   N   S   D   G
  M24680  ,IGHV8S1*01           TGG ACC TGG CAG GCT CCT GGT AAA GGA CTG GAG TAT ATA GGT TAT TTA AAC AGC GAC GGG

                                GT__________________
                                 61  62  63  64  65  66  67  68  69  70  71  72  73  74  75  76  77  78  79  80
                                 S   S               Y   P   A   P   S   F   Q       S   R   V   T   L   T   R
  M24680  ,IGHV8S1*01           AGC TCT ... ... ... TAC CCA GCC CCC TCA TTT CAA ... AGT CGA GTC ACG CTC ACC AGG

                                 81  82  83  84  85  86  87  88  89  90  91  92  93  94  95  96  97  98  99 100
                                 D   S   S   K   N   E   I   S   L   Q   M   T   S   M   K   S   E   D   S   G
  M24680  ,IGHV8S1*01           GAC AGC TCA AAG AAT GAA ATT TCC TTA CAA ATG ACC AGT ATG AAA AGT GAA GAT TCT GGG

                                                CDR3-IMGT__
                                101 102 103 104 105 106
                                 T   Y   Y   C   A   N
  M24680  ,IGHV8S1*01           ACA TAT TAC TGT GCA AAC #c
#c : rearranged cDNA

This alignment has been generated with the IMGT/AlleleAlign tool developed by Mehdi Yousfi (31/07/2001)

Created: 06/08/2003
Author: Delphine Guiraudou