This table lists reagents monoclonal antibodies, specific for the T cell Receptor Gamma Variable regions (TRGV), which are commercially available.
Companies are encouraged to inform us of commercially available antibodies.
Only functional TRGV genes and alleles are listed.
The reactivities of the reagents monoclonal antibodies for different variable regions are shown between parentheses in the 'Clone name and Specificity' column.
% of peripheral CD3 positive cells in normal blood are from the Coulter, Serotec or BD Biosciences Web sites.
The reactivities as described in this table are not exhaustive. For more information on the products and their reactivity, please contact the companies.
For antibodies quoted in the table: ThermoFisher Scientific (Pierce Endogen antibodies), Bio-rad (Serotec antibodies), Beckman Coulter (Coulter antibodies), and BD Biosciences
TRGV gene name | TRGV allele name | Reagents monoclonal antibodies | |||
Clone name and Specificity | Company product | Isotype | % of peripheral CD3 positive cells in normal blood |
||
TRGV2 | TRGV2*01 | 23D12 (TRGV2, TRGV3 and TRGV4) | Serotec V GAMMA 2/3/4 | Mouse IgG1 | |
TRGV2*02 | |||||
TRGV3 | TRGV3*01 | 23D12 (TRGV2, TRGV3 and TRGV4) | Serotec V GAMMA 2/3/4 | Mouse IgG1 | |
TRGV3*02 | |||||
TRGV4 | TRGV4*01 | 23D12 (TRGV2, TRGV3 and TRGV4) | Serotec> V GAMMA 2/3/4 | Mouse IgG1 | |
TRGV4*02 | |||||
TRGV5 | TRGV5*01 | ||||
TRGV8 | TRGV8*01 | ||||
TRGV9 | TRGV9*01 | IMMU360 (TRGV9) B3.1 (TRGV9) |
Serotec VGAMMA9 Coulter Vgamma9 |
Mouse IgG1 | 0.9-3.6 |
TRGV9*02 | |||||
BD Biosciences Vgamma9 | Mouse IgG1 |
Created: Friday, 22-Sep-2023 18:31:09 CEST
Author: Géraldine Folch