Mouse (Mus musculus) H2 genes are located on chromosome 17 (18.40-20.05 cM). They are listed by alphabetic order.
MHC class | MHC subclass | IMGT gene names (1) | Other designations from the literature (1) |
---|---|---|---|
IIa | H2-A | MH2-AA | H2-Aa, H-2Aa, H2-IA-alpha,
I-A D-A, I-A K-A, I-Aa, Ia1, Ia-1, I-A-alpha, I-A alpha, IA alpha, Aalpha, A-alpha, A alpha |
H2-AB (2) | H2-Ab, H-2Ab, H2-Ab1, H2-IA-beta, H2 I-A beta, I-A D-B, I-A K-B, I-Ab, Ia2, Ia-2, I-A-beta, I-A beta, IA beta 1, Iab, Abeta, A beta |
||
Ia | H2-D | H2-D1 | H-2 D-B, H-2 D-D, H-2D, Db, Dd |
H2-D2 | D2d | ||
H2-D3 | D3d | ||
H2-D4 | D4d | ||
IIb | H2-DM | H2-DMA | H2-DMa, H-2Ma, Ma [2], H2-M alpha |
H2-DMB1 | H2-DMb1, H-2Mb1, Mb1 [2] (8), H2-M beta1 | ||
H2-DMB2 | H2-DMb2, H-2Mb2, Mb2 [2], H2-M beta2 | ||
IIa | H2-E | H2-EA | H2-Ea, H-2E alpha, H2-IE-alpha, I-E K-A, I-Ea, IE alpha, Ia-3, Ia3, E alpha |
H2-EB1 | H2-Eb1, H2-Eb, H-2E beta, H2-IE-beta, I-E K-B, I-Eb, I-E beta, I-E-beta-1, Ia-4, Ia4, E beta |
||
H2-EB2 | H2-Eb2, E-beta 2, I-Eb2, Ia-5, Ia5 | ||
Ia | H2-K | MH1-K1 | H2-K, H-2K, H-2 K, H-2K1, H2K |
H2-K2 | H-2K2 | ||
Ia | H2-L | H2-L | H-2L |
Ib (nonclassical I) (3) |
H2-M | H2-M1 | H-2M1, Mb1 [3] (8) |
H2-M2 | H-2M2, Thy19.4 [4] | ||
H2-M3 | H-2M3, R4B2 [5] | ||
H2-M4 | H-2M4, C3R1 [5] | ||
H2-M5 | H-2M5, CRW2 [5] | ||
H2-M6 | H-2M6, CRW3 [5] | ||
H2-M7 | H-2M7, M7 [6] | ||
H2-M8 | H-2M8, M8 [6] | ||
H2-M9 | H-2M9, M9 [7] | ||
H2-M10-1 | H2-M10.1, H-2M10, 9.5H [7] | ||
H2-M10-2 | H2-M10.2, 4.7H | ||
H2-M10-3 | H2-M10.3, 5.3H | ||
H2-M10-4 | H2-M10.4, 15H | ||
H2-M10-5 | H2-M10.5, 6.9H | ||
H2-M10-PS1 | H2-M10-ps1, 13H | ||
H2-M10-PS2 | H2-M10-ps2, 5.4H | ||
H2-M10-PS3 | H2-M10-ps3, 7.2H | ||
IIb | H2-O | H2-OA (6) | Oa, H2-Oa, H-2Oa |
H2-OB | Ob, H2-Ob, H-2Ob, H2-IA-beta-2, H2-Iab2, H2-Ab2, A-beta-2, A beta2 |
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IIa | H2-P | H2-PA | H2-Pa |
H2-PB | Pb, H2-Pb, H-2Pb, H2-Ab3, Ia7, A beta3 | ||
Ib (nonclassical I) (4) |
H2-Q | H2-Q1 | H-2Q1, Q1b, Q1d, Q1k |
H2-Q2 | H-2Q2, Q2b, Q2d, Q2k | ||
H2-Q3 | H-2Q3, Q3b | ||
H2-Q4 | H-2Q4, Q4b, Q4d, Q4k | ||
H2-Q5 | H-2Q5, Q5B, Q5b, Q5d, Q5d, Q5/9k | ||
H2-Q6 | H-2Q6, Q6b, Q6b, Q6d | ||
H2-Q7 | H-2Q7, Q7b, Q7d | ||
H2-Q8 | H-2Q8, Q8b, Q8/9d | ||
H2-Q9 | H-2Q9, Q9b | ||
H2-Q10 | H-2Q10, Q-10, Q10b, Q10d, Q10k | ||
Ib (nonclassical I) (5) |
H2-T | H2-T1 | H-2T1, T1b, T1c, T1d |
H2-T2 | H-2T2, T2b, T2c, T2d, T2Aa | ||
H2-T3 | H-2T3, T3b, T3c, T3d | ||
H2-T4 | H-2T4, T4b, 5'c, T4d | ||
H2-T5 | H-2T5, T5b, T4c, T5d | ||
H2-T6 | H-2T6, T6b, T5c, T6d | ||
H2-T7 | H-2T7, T7b, T6c, T7d | ||
H2-T8 | H-2T8, T8b, T7c, T8d | ||
H2-T9 | H-2T9, T9b, T8c, T9d | ||
H2-T10 | H-2T10, T10b, T9c, T10d, H2-TL-T10-129, H2-TL-T10-b, H2-TL-T9-c |
||
H2-T11 | H-2T11, T11b, T10c, T11d, T10-c | ||
H2-T12 | H-2T12, T12b | ||
H2-T13 | H-2T13, T13b, T13-b | ||
H2-T14 | H-2T14, T14b | ||
H2-T15 | H-2T15, T15b | ||
H2-T16 | H-2T16, T11c, T16d | ||
H2-T17 | H-2T17, T12c, T17d | ||
H2-T18 | H-2T18, T13c, T18d, T13-c | ||
H2-T19 | H-2T19, T14c, T19d | ||
H2-T20 | H-2T20, T15c, T20d | ||
H2-T21 | H-2T21, T21d, T16c, 26b | ||
H2-T22 | H-2T22, T22b, T17c [8], T22d, 27b [9] [10],
27129, H2-TL-27-129, H2-TL-27-b, H2-TL-17-c |
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H2-T23 (7) | H-2T23, T23b, T23d, 37b [9] , 37c, T18c, T18c(37) [11] | ||
H2-T24 | H-2T24, T24d |
(1) | In IMGT gene names, the "H-2" prefix [1] is replaced by the "H2-" prefix according to the MGI Nomenclature Committee and by analogy with the "HLA-" prefix. |
(2) | In MGD: H2-Ab1. |
(3) | H2-M genes encode Hmt antigens. |
(4) | H2-Q4 encodes the Qb-1 antigen.
H2-Q6 to H2-Q9 genes encode the Qa-2 antigen. H2-Q10 gene encodes the Q10 antigen [11]. |
(5) | H2-T3b, H2-T3c and H2-T13c genes encode TL antigens
[11].
H2-T23 encodes the Qa-1 antigen. |
(6) | Murine equivalent of the human HLA-DOA gene. |
(7) | H2-T23, which encodes the Qa-1 antigen, is probably orthologous to human HLA-E [12]. |
(8) | The two different genes, previously designated as Mb1, correspond to H2-DMB1 and H2-M1, respectively [13]. |
[1] | Klein, J. et al., Immunogenetics, 32, 147-149 (1990). PMID: 2329006 |
[2] | Cho et al., Nature, 353, 571-576 (1991). PMID: 1922366 |
[3] | Singer, D.S. et al., Immunogenetics, 28, 13-21 (1988). PMID: 3378834 |
[4] | Brorson, K.A. et al., Immunogenetics, 30, 273-283 (1989). PMID: 2793207 |
[5] | Richards, S. et al., EMBO J., 8, 3749-3757 (1989). PMID: 2573520 |
[6] | Wang, C.R. and Lindahl, K.F., Immunogenetics, 38, 258-271 (1993). PMID: 8319975 |
[7] | Arepalli, S.R. et al., Immunogenetics, 47, 264-271 (1998). PMID: 9435345 |
[8] | Transy et al., J. Exp. Med., 166, 341-361 (1987). PMID: 3036997 |
[9] | Ito et al., Cell, 62, 549-561 (1990). PMID: 2379238 |
[10] | Transy et al., Cell, 41, 469-478 (1985). PMID: 3838699 |
[11] | Flaherty et al., Crit. Rev. Immunol., 10, 131-175 (1990). PMID: 2076187 |
[12] | Kronenberg, M. et al., Immunol. Today, 20, 515-521 (1999). PMID: 10529780 |
[13] | Rodgers et al., J. Immunol., 162, 6294 (1999). PMID: 13075304 |