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IMGT/PROTEIN-DB and IMGT/3Dstructure-DB:
Standardized keywords and labels for IG, TR, MH, RPI and FPIA

Keywords, listed in this table, are used to identify the receptor type and the chain type of IG, TR, MH, RPI and FPIA. They are instances of the IDENTIFICATION axiom of IMGT-ONTOLOGY.

Labels, listed in this table, are used to describe the 2D and 3D structure organization of IG, TR, MH, RPI and FPIA receptors into chains and domains (2). They are instances of the DESCRIPTION concept of IMGT-ONTOLOGY.

Click below for standardized keywords and labels of:

Click here for IMGT/PROTEIN-DB and IMGT/3Dstructure-DB: Label definitions for IG, TR and MH.

IMGT/PROTEIN-DB and IMGT/3Dstructure-DB keywords and labels: IG complete receptors

Mammals

IDENTIFICATION Standardized labels for DESCRIPTION
Receptor type Chain type Receptor (1) Chain Domain (2)
IgA_Kappa IG-Heavy-Alpha IG-ALPHA_KAPPA H-ALPHA VH, CH1, CH2, CH3
IG-Light-Kappa L-KAPPA V-KAPPA, C-KAPPA
IgA1_Kappa IG-Heavy-Alpha-1 IG-ALPHA-1_KAPPA H-ALPHA-1 VH, CH1, CH2, CH3
IG-Light-Kappa L-KAPPA V-KAPPA, C-KAPPA
IgA2_Kappa IG-Heavy-Alpha-2 IG-ALPHA-2_KAPPA H-ALPHA-2 VH, CH1, CH2, CH3
IG-Light-Kappa L-KAPPA V-KAPPA, C-KAPPA
IgD_Kappa IG-Heavy-Delta IG-DELTA_KAPPA H-DELTA VH, CH1, CH2, CH3
IG-Light-Kappa L-KAPPA V-KAPPA, C-KAPPA
IgE_Kappa IG-Heavy-Epsilon IG-EPSILON_KAPPA H-EPSILON VH, CH1, CH2, CH3, CH4
IG-Light-Kappa L-KAPPA V-KAPPA, C-KAPPA
IgG_Kappa IG-Heavy-Gamma IG-GAMMA_KAPPA H-GAMMA VH, CH1, CH2, CH3
IG-Light-Kappa L-KAPPA V-KAPPA, C-KAPPA
IgG1_Kappa IG-Heavy-Gamma-1 IG-GAMMA-1_KAPPA H-GAMMA-1 VH, CH1, CH2, CH3
IG-Light-Kappa L-KAPPA V-KAPPA, C-KAPPA
IgG2_Kappa IG-Heavy-Gamma-2 IG-GAMMA-2_KAPPA H-GAMMA-2 VH, CH1, CH2, CH3
IG-Light-Kappa L-KAPPA V-KAPPA, C-KAPPA
IgG2a_Kappa IG-Heavy-Gamma-2-a IG-GAMMA-2-A_KAPPA H-GAMMA-2-A VH, CH1, CH2, CH3
IG-Light-Kappa L-KAPPA V-KAPPA, C-KAPPA
IgG2b_Kappa IG-Heavy-Gamma-2-b IG-GAMMA-2-B_KAPPA H-GAMMA-2-B VH, CH1, CH2, CH3
IG-Light-Kappa L-KAPPA V-KAPPA, C-KAPPA
IgG2c_Kappa IG-Heavy-Gamma-2-c IG-GAMMA-2-C_KAPPA H-GAMMA-2-C VH, CH1, CH2, CH3
IG-Light-Kappa L-KAPPA V-KAPPA, C-KAPPA
IgG3_Kappa IG-Heavy-Gamma-3 IG-GAMMA-3_KAPPA H-GAMMA-3 VH, CH1, CH2, CH3
IG-Light-Kappa L-KAPPA V-KAPPA, C-KAPPA
IgG4_Kappa IG-Heavy-Gamma-4 IG-GAMMA-4_KAPPA H-GAMMA-4 VH, CH1, CH2, CH3
IG-Light-Kappa L-KAPPA V-KAPPA, C-KAPPA
IgM_Kappa IG-Heavy-Mu IG-MU_KAPPA H-MU VH, CH1, CH2, CH3, CH4
IG-Light-Kappa L-KAPPA V-KAPPA, C-KAPPA
IgA_Lambda
(3)
IG-Heavy-Alpha IG-ALPHA_LAMBDA H-ALPHA VH, CH1, CH2, CH3
IG-Light-Lambda L-LAMBDA V-LAMBDA, C-LAMBDA
IgA1_Lambda
(3)
IG-Heavy-Alpha-1 IG-ALPHA-1_LAMBDA H-ALPHA-1 VH, CH1, CH2, CH3
IG-Light-Lambda L-LAMBDA V-LAMBDA, C-LAMBDA
IgA2_Lambda
(3)
IG-Heavy-Alpha-2 IG-ALPHA-2_LAMBDA H-ALPHA-2 VH, CH1, CH2, CH3
IG-Light-Lambda L-LAMBDA V-LAMBDA, C-LAMBDA
IgD_Lambda
(3)
IG-Heavy-Delta IG-DELTA_LAMBDA H-DELTA VH, CH1, CH2, CH3
IG-Light-Lambda L-LAMBDA V-LAMBDA, C-LAMBDA
IgE_Lambda
(3)
IG-Heavy-Epsilon IG-EPSILON_LAMBDA H-EPSILON VH, CH1, CH2, CH3, CH4
IG-Light-Lambda L-LAMBDA V-LAMBDA, C-LAMBDA
IgG_Lambda
(3)
IG-Heavy-Gamma IG-GAMMA_LAMBDA H-GAMMA VH, CH1, CH2, CH3
IG-Light-Lambda L-LAMBDA V-LAMBDA, C-LAMBDA
IgG1_Lambda
(3)
IG-Heavy-Gamma-1 IG-GAMMA-1_LAMBDA H-GAMMA-1 VH, CH1, CH2, CH3
IG-Light-Lambda L-LAMBDA V-LAMBDA, C-LAMBDA
IgG2_Lambda
(3)
IG-Heavy-Gamma-2 IG-GAMMA-2_LAMBDA H-GAMMA-2 VH, CH1, CH2, CH3
IG-Light-Lambda L-LAMBDA V-LAMBDA, C-LAMBDA
IgG2a_Lambda
(3)
IG-Heavy-Gamma-2-a IG-GAMMA-2-A_LAMBDA H-GAMMA-2-A VH, CH1, CH2, CH3
IG-Light-Lambda L-LAMBDA V-LAMBDA, C-LAMBDA
IgG2b_Lambda
(3)
IG-Heavy-Gamma-2-b IG-GAMMA-2-B_LAMBDA H-GAMMA-2-B VH, CH1, CH2, CH3
IG-Light-Lambda L-LAMBDA V-LAMBDA, C-LAMBDA
IgG2c_Lambda
(3)
IG-Heavy-Gamma-2-c IG-GAMMA-2-C_LAMBDA H-GAMMA-2-C VH, CH1, CH2, CH3
IG-Light-Lambda L-LAMBDA V-LAMBDA, C-LAMBDA
IgG3_Lambda
(3)
IG-Heavy-Gamma-3 IG-GAMMA-3_LAMBDA H-GAMMA-3 VH, CH1, CH2, CH3
IG-Light-Lambda L-LAMBDA V-LAMBDA, C-LAMBDA
IgM_Lambda
(3)
IG-Heavy-Mu IG-MU_LAMBDA H-MU VH, CH1, CH2, CH3, CH4
IG-Light-Lambda L-LAMBDA V-LAMBDA, C-LAMBDA

Teleostei

IDENTIFICATION Standardized labels for DESCRIPTION
Receptor type Chain type Receptor Chain Domain
IgM_Iota IG-Heavy-Mu IG-MU_IOTA H-MU VH, CH1, CH2, CH3
IG-Light-Iota L-IOTA V-IOTA, C-IOTA
IgM_Iota-1 IG-Heavy-Mu IG-MU_IOTA-1 H-MU VH, CH1, CH2, CH3
IG-Light-Iota-1 L-IOTA-1 V-IOTA, C-IOTA-1
IgM_Iota-2 IG-Heavy-Mu IG-MU_IOTA-2 H-MU VH, CH1, CH2, CH3
IG-Light-Iota-2 L-IOTA-2 V-IOTA, C-IOTA-2
IgM_Iota-3 IG-Heavy-Mu IG-MU_IOTA-3 H-MU VH, CH1, CH2, CH3
IG-Light-Iota-3 L-IOTA-3 V-IOTA, C-IOTA-3
IgM_Iota-4 IG-Heavy-Mu IG-MU_IOTA-4 H-MU VH, CH1, CH2, CH3
IG-Light-Iota-4 L-IOTA-4 V-IOTA, C-IOTA-4

IMGT/PROTEIN-DB and IMGT/3Dstructure-DB keywords and labels: TR complete and partial receptors

IDENTIFICATION Standardized labels for DESCRIPTION
Receptor type Chain type Receptor Chain Domain
TR-Alpha_Beta TR-Alpha TR-ALPHA_BETA TR-ALPHA V-ALPHA, C-ALPHA
TR-Beta TR-BETA V-BETA, C-BETA
TR-Alpha_Beta-1 TR-Alpha TR-ALPHA_BETA-1 TR-ALPHA V-ALPHA, C-ALPHA
TR-Beta-1 TR-BETA-1 V-BETA, C-BETA-1
TR-Alpha_Beta-2 TR-Alpha TR-ALPHA_BETA-2 TR-ALPHA V-ALPHA, C-ALPHA
TR-Beta-2 TR-BETA-2 V-BETA, C-BETA-2
TR-Gamma_Delta TR-Gamma TR-GAMMA_DELTA TR-GAMMA V-GAMMA, C-GAMMA
TR-Delta TR-DELTA V-DELTA, C-DELTA
TR-Gamma-1_Delta TR-Gamma-1 TR-GAMMA-1_DELTA TR-GAMMA-1 V-GAMMA, C-GAMMA-1
TR-Delta TR-DELTA V-DELTA, C-DELTA
TR-Gamma-2_Delta TR-Gamma-2 TR-GAMMA-2_DELTA TR-GAMMA-2 V-GAMMA, C-GAMMA-2
TR-Delta TR-DELTA V-DELTA, C-DELTA
TR-Gamma-3_Delta TR-Gamma-3 TR-GAMMA-3_DELTA TR-GAMMA-3 V-GAMMA, C-GAMMA-3
TR-Delta TR-DELTA V-DELTA, C-DELTA
TR-Gamma-4_Delta TR-Gamma-4 TR-GAMMA-4_DELTA TR-GAMMA-4 V-GAMMA, C-GAMMA-4
TR-Delta TR-DELTA V-DELTA, C-DELTA
TR-Gamma-5_Delta TR-Gamma-5 TR-GAMMA-5_DELTA TR-GAMMA-5 V-GAMMA, C-GAMMA-5
TR-Delta TR-DELTA V-DELTA, C-DELTA
Fv-Alpha_Beta TR-Alpha FV-ALPHA_BETA V-ALPHA V-ALPHA
TR-Beta V-BETA V-BETA
Fv-Gamma_Delta TR-Gamma FV-GAMMA_DELTA V-GAMMA V-GAMMA
TR-Delta V-DELTA V-DELTA

IMGT/PROTEIN-DB and IMGT/3Dstructure-DB keywords and labels: MH complete receptors

The same standardized labels for DESCRIPTION are used for the description of the "classical " and "nonclassical" MH receptors, chains and domains.

IDENTIFICATION Standardized labels for DESCRIPTION
Receptor type Chain type Receptor Chain Domain (4)
MH1 MH1-Alpha MH1-ALPHA_B2M MH1-ALPHA G-ALPHA1, G-ALPHA2, C-LIKE
Beta2-Microglobulin B2M C-LIKE
MH2 MH2-Alpha MH2-ALPHA_BETA MH2-ALPHA G-ALPHA, C-LIKE
MH2-Beta MH2-BETA G-BETA, C-LIKE

IMGT/PROTEIN-DB and IMGT/3Dstructure-DB keywords and labels: RPI complete receptors

RPI comprise a few proteins belonging to the MhSF. Keywords and labels for these receptors are shown in the table below.

IDENTIFICATION Standardized labels for DESCRIPTION
Receptor type Chain type Receptor Chain Domain (4)
RPI-MH1Like RPI-MH1Like-Alpha MH1LIKE-ALPHA_B2M MH1LIKE-ALPHA G-ALPHA1-LIKE, G-ALPHA2-LIKE, C-LIKE (5)
Beta2-Microglobulin B2M C-LIKE (5)
RPI-MH1Like-Alpha MH1LIKE-ALPHA MH1LIKE-ALPHA G-ALPHA1-LIKE, G-ALPHA2-LIKE, C-LIKE (5)

RPI comprise many proteins belonging to the IgSF (not detailed here). These proteins possess at least one chain with V-LIKE or C-LIKE domain.

IMGT/PROTEIN-DB and IMGT/3Dstructure-DB keywords and labels: IG proteolytic fragments

IDENTIFICATION Standardized labels for DESCRIPTION
Receptor type Chain type (6) Receptor Chain Domain
Fab-Alpha_Kappa IG-Heavy-Alpha FAB-ALPHA_KAPPA VH-CH1 VH, CH1
IG-Light-Kappa L-KAPPA V-KAPPA, C-KAPPA
Fab-Alpha-1_Kappa IG-Heavy-Alpha-1 FAB-ALPHA-1_KAPPA VH-CH1 VH, CH1
IG-Light-Kappa L-KAPPA V-KAPPA, C-KAPPA
Fab-Alpha-2_Kappa IG-Heavy-Alpha-2 FAB-ALPHA-2_KAPPA VH-CH1 VH, CH1
IG-Light-Kappa L-KAPPA V-KAPPA, C-KAPPA
Fab-Delta_Kappa IG-Heavy-Delta FAB-DELTA_KAPPA VH-CH1 VH, CH1
IG-Light-Kappa L-KAPPA V-KAPPA, C-KAPPA
Fab-Epsilon_Kappa IG-Heavy-Epsilon FAB-EPSILON_KAPPA VH-CH1 VH, CH1
IG-Light-Kappa L-KAPPA V-KAPPA, C-KAPPA
Fab-Gamma_Kappa Ig-Heavy-Gamma FAB-GAMMA_KAPPA VH-CH1 VH, CH1
IG-Light-Kappa L-KAPPA V-KAPPA, C-KAPPA
Fab-Gamma-1_Kappa IG-Heavy-Gamma-1 FAB-GAMMA-1_KAPPA VH-CH1 VH, CH1
IG-Light-Kappa L-KAPPA V-KAPPA, C-KAPPA
Fab-Gamma-2_Kappa IG-Heavy-Gamma-2 FAB-GAMMA-2_KAPPA VH-CH1 VH, CH1
IG-Light-Kappa L-KAPPA V-KAPPA, C-KAPPA
Fab-Gamma-2-a_Kappa IG-Heavy-Gamma-2-a FAB-GAMMA-2-A_KAPPA VH-CH1 VH, CH1
IG-Light-Kappa L-KAPPA V-KAPPA, C-KAPPA
Fab-Gamma-2-b_Kappa IG-Heavy-Gamma-2-b FAB-GAMMA-2-B_KAPPA VH-CH1 VH, CH1
IG-Light-Kappa L-KAPPA V-KAPPA, C-KAPPA
Fab-Gamma-2-c_Kappa IG-Heavy-Gamma-2-c FAB-GAMMA-2-C_KAPPA VH-CH1 VH, CH1
IG-Light-Kappa L-KAPPA V-KAPPA, C-KAPPA
Fab-Gamma-3_Kappa IG-Heavy-Gamma-3 FAB-GAMMA-3_KAPPA VH-CH1 VH, CH1
IG-Light-Kappa L-KAPPA V-KAPPA, C-KAPPA
Fab-Gamma-4_Kappa IG-Heavy-Gamma-4 FAB-GAMMA-4_KAPPA VH-CH1 VH, CH1
IG-Light-Kappa L-KAPPA V-KAPPA, C-KAPPA
Fab-Mu_Kappa IG-Heavy-Mu FAB-MU_KAPPA VH-CH1 VH, CH1
IG-Light-Kappa L-KAPPA V-KAPPA, C-KAPPA
Fab-Alpha_Lambda
(3)
IG-Heavy-Alpha FAB-ALPHA_LAMBDA VH-CH1 VH, CH1
IG-Light-Lambda L-LAMBDA V-LAMBDA, C-LAMBDA
Fab-Alpha-1_Lambda
(3)
IG-Heavy-Alpha-1 FAB-ALPHA-1_LAMBDA VH-CH1 VH, CH1
IG-Light-Lambda L-LAMBDA V-LAMBDA, C-LAMBDA
Fab-Alpha-2_Lambda
(3)
IG-Heavy-Alpha-2 FAB-ALPHA-2_LAMBDA VH-CH1 VH, CH1
IG-Light-Lambda L-LAMBDA V-LAMBDA, C-LAMBDA
Fab-Delta_Lambda
(3)
IG-Heavy-Delta FAB-DELTA_LAMBDA VH-CH1 VH, CH1
IG-Light-Lambda L-LAMBDA V-LAMBDA, C-LAMBDA
Fab-Epsilon_Lambda
(3)
IG-Heavy-Epsilon FAB-EPSILON_LAMBDA VH-CH1 VH, CH1
IG-Light-Lambda L-LAMBDA V-LAMBDA, C-LAMBDA
Fab-Gamma-1_Lambda
(3)
IG-Heavy-Gamma-1 FAB-GAMMA-1_LAMBDA VH-CH1 VH, CH1
IG-Light-Lambda L-LAMBDA V-LAMBDA, C-LAMBDA
Fab-Gamma-2_Lambda
(3)
IG-Heavy-Gamma-2 FAB-GAMMA-2_LAMBDA VH-CH1 VH, CH1
IG-Light-Lambda L-LAMBDA V-LAMBDA, C-LAMBDA
Fab-Gamma-2-a_Lambda
(3)
IG-Heavy-Gamma-2-a FAB-GAMMA-2-A_LAMBDA VH-CH1 VH, CH1
IG-Light-Lambda L-LAMBDA V-LAMBDA, C-LAMBDA
Fab-Gamma-2-b_Lambda
(3)
IG-Heavy-Gamma-2-b FAB-GAMMA-2-B_LAMBDA VH-CH1 VH, CH1
IG-Light-Lambda L-LAMBDA V-LAMBDA, C-LAMBDA
Fab-Gamma-2-c_Lambda
(3)
IG-Heavy-Gamma-2-c FAB-GAMMA-2-C_LAMBDA VH-CH1 VH, CH1
IG-Light-Lambda L-LAMBDA V-LAMBDA, C-LAMBDA
Fab-Gamma-3_Lambda
(3)
IG-Heavy-Gamma-3 FAB-GAMMA-3_LAMBDA VH-CH1 VH, CH1
IG-Light-Lambda L-LAMBDA V-LAMBDA, C-LAMBDA
Fab-Gamma-4_Lambda
(3)
IG-Heavy-Gamma-4 FAB-GAMMA-4_LAMBDA VH-CH1 VH, CH1
IG-Light-Lambda L-LAMBDA V-LAMBDA, C-LAMBDA
Fab-Mu_Lambda
(3)
IG-Heavy-Mu FAB-MU_LAMBDA VH-CH1 VH, CH1
IG-Light-Lambda L-LAMBDA V-LAMBDA, C-LAMBDA
F(ab')2-Alpha_Kappa IG-Heavy-Alpha F(AB')2-ALPHA_KAPPA VH-CH1 VH, CH1
IG-Light-Kappa L-KAPPA V-KAPPA, C-KAPPA
F(ab')2-Alpha-1_Kappa IG-Heavy-Alpha-1 F(AB')2-ALPHA-1_KAPPA VH-CH1 VH, CH1
IG-Light-Kappa L-KAPPA V-KAPPA, C-KAPPA
F(ab')2-Alpha-2_Kappa IG-Heavy-Alpha-2 F(AB')2-ALPHA-2_KAPPA VH-CH1 VH, CH1
IG-Light-Kappa L-KAPPA V-KAPPA, C-KAPPA
F(ab')2-Delta_Kappa IG-Heavy-Delta F(AB')2-DELTA_KAPPA VH-CH1 VH, CH1
IG-Light-Kappa L-KAPPA V-KAPPA, C-KAPPA
F(ab')2-Epsilon_Kappa IG-Heavy-Epsilon F(AB')2-EPSILON_KAPPA VH-CH1 VH, CH1
IG-Light-Kappa L-KAPPA V-KAPPA, C-KAPPA
F(ab')2-Gamma-1_Kappa IG-Heavy-Gamma-1 F(AB')2-GAMMA-1_KAPPA VH-CH1 VH, CH1
IG-Light-Kappa L-KAPPA V-KAPPA, C-KAPPA
F(ab')2-Gamma-2_Kappa IG-Heavy-Gamma-2 F(AB')2-GAMMA-2_KAPPA VH-CH1 VH, CH1
IG-Light-Kappa L-KAPPA V-KAPPA, C-KAPPA
F(ab')2-Gamma-2-a_Kappa IG-Heavy-Gamma-2-a F(AB')2-GAMMA-2-A_KAPPA VH-CH1 VH, CH1
IG-Light-Kappa L-KAPPA V-KAPPA, C-KAPPA
F(ab')2-Gamma-2-b_Kappa IG-Heavy-Gamma-2-b F(AB')2-GAMMA-2-B_KAPPA VH-CH1 VH, CH1
IG-Light-Kappa L-KAPPA V-KAPPA, C-KAPPA
F(ab')2-Gamma-2-c_Kappa IG-Heavy-Gamma-2-c F(AB')2-GAMMA-2-C_KAPPA VH-CH1 VH, CH1
IG-Light-Kappa L-KAPPA V-KAPPA, C-KAPPA
F(ab')2-Gamma-3_Kappa IG-Heavy-Gamma-3 F(AB')2-GAMMA-3_KAPPA VH-CH1 VH, CH1
IG-Light-Kappa L-KAPPA V-KAPPA, C-KAPPA
F(ab')2-Gamma-4_Kappa IG-Heavy-Gamma-4 F(AB')2-GAMMA-4_KAPPA VH-CH1 VH, CH1
IG-Light-Kappa L-KAPPA V-KAPPA, C-KAPPA
F(ab')2-Mu_Kappa IG-Heavy-Mu F(AB')2-MU_KAPPA VH-CH1 VH, CH1
IG-Light-Kappa L-KAPPA V-KAPPA, C-KAPPA
F(ab')2-Alpha_Lambda
(3)
IG-Heavy-Alpha F(AB')2-ALPHA_LAMBDA VH-CH1 VH, CH1
IG-Light-Lambda L-LAMBDA V-LAMBDA, C-LAMBDA
F(ab')2-Alpha-1_Lambda
(3)
IG-Heavy-Alpha-1 F(AB')2-ALPHA-1_LAMBDA VH-CH1 VH, CH1
IG-Light-Lambda L-LAMBDA V-LAMBDA, C-LAMBDA
F(ab')2-Alpha-2_Lambda
(3)
IG-Heavy-Alpha-2 F(AB')2-ALPHA-2_LAMBDA VH-CH1 VH, CH1
IG-Light-Lambda L-LAMBDA V-LAMBDA, C-LAMBDA
F(ab')2-Delta_Lambda
(3)
IG-Heavy-Delta F(AB')2-DELTA_LAMBDA VH-CH1 VH, CH1
IG-Light-Lambda L-LAMBDA V-LAMBDA, C-LAMBDA
F(ab')2-Epsilon_Lambda
(3)
IG-Heavy-Epsilon F(AB')2-EPSILON_LAMBDA VH-CH1 VH, CH1
IG-Light-Lambda L-LAMBDA V-LAMBDA, C-LAMBDA
F(ab')2-Gamma-1_Lambda
(3)
IG-Heavy-Gamma-1 F(AB')2-GAMMA-1_LAMBDA VH-CH1 VH, CH1
IG-Light-Lambda L-LAMBDA V-LAMBDA, C-LAMBDA
F(ab')2-Gamma-2_Lambda
(3)
IG-Heavy-Gamma-2 F(AB')2-GAMMA-2_LAMBDA VH-CH1 VH, CH1
IG-Light-Lambda L-LAMBDA V-LAMBDA, C-LAMBDA
F(ab')2-Gamma-2-a_Lambda
(3)
IG-Heavy-Gamma-2-a F(AB')2-GAMMA-2-A_LAMBDA VH-CH1 VH, CH1
IG-Light-Lambda L-LAMBDA V-LAMBDA, C-LAMBDA
F(ab')2-Gamma-2-b_Lambda
(3)
IG-Heavy-Gamma-2-b F(AB')2-GAMMA-2-B_LAMBDA VH-CH1 VH, CH1
IG-Light-Lambda L-LAMBDA V-LAMBDA, C-LAMBDA
F(ab')2-Gamma-2-c_Lambda
(3)
IG-Heavy-Gamma-2-c F(AB')2-GAMMA-2-C_LAMBDA VH-CH1 VH, CH1
IG-Light-Lambda L-LAMBDA V-LAMBDA, C-LAMBDA
F(ab')2-Gamma-3_Lambda
(3)
IG-Heavy-Gamma-3 F(AB')2-GAMMA-3_LAMBDA VH-CH1 VH, CH1
IG-Light-Lambda L-LAMBDA V-LAMBDA, C-LAMBDA
F(ab')2-Gamma-4_Lambda
(3)
IG-Heavy-Gamma-4 F(AB')2-GAMMA-4_LAMBDA VH-CH1 VH, CH1
IG-Light-Lambda L-LAMBDA V-LAMBDA, C-LAMBDA
F(ab')2-Mu_Lambda
(3)
IG-Heavy-Mu F(AB')2-MU_LAMBDA VH-CH1 VH, CH1
IG-Light-Lambda L-LAMBDA V-LAMBDA, C-LAMBDA
Fc-Alpha IG-Heavy-Alpha FC-ALPHA CH2-CH3 CH2, CH3
Fc-Alpha-1 IG-Heavy-Alpha-1 FC-ALPHA-1 CH2-CH3 CH2, CH3
Fc-Alpha-2 IG-Heavy-Alpha-2 FC-ALPHA-2 CH2-CH3 CH2, CH3
Fc-Delta IG-Heavy-Delta FC-DELTA CH2-CH3 CH2, CH3
Fc-Epsilon IG-Heavy-Epsilon FC-EPSILON CH2-CH3-CH4 CH2, CH3, CH4
Fc-Gamma-1 IG-Heavy-Gamma-1 FC-GAMMA-1 CH2-CH3 CH2, CH3
Fc-Gamma-2 IG-Heavy-Gamma-2 FC-GAMMA-2 CH2-CH3 CH2, CH3
Fc-Gamma-2-a IG-Heavy-Gamma-2-a FC-GAMMA-2-A CH2-CH3 CH2, CH3
Fc-Gamma-2-b IG-Heavy-Gamma-2-b FC-GAMMA-2-B CH2-CH3 CH2, CH3
Fc-Gamma-2-c IG-Heavy-Gamma-2-c FC-GAMMA-2-C CH2-CH3 CH2, CH3
Fc-Gamma-3 IG-Heavy-Gamma-3 FC-GAMMA-3 CH2-CH3 CH2, CH3
Fc-Gamma-4 IG-Heavy-Gamma-4 FC-GAMMA-4 CH2-CH3 CH2, CH3
Fc-Mu IG-Heavy-Mu FC-MU CH2-CH3-CH4 CH2, CH3, CH4
Fv-Heavy_Kappa IG-Heavy FV-HEAVY_KAPPA VH VH
IG-Light-Kappa V-KAPPA V-KAPPA
Fv-Heavy_Lambda
(3)
IG-Heavy FV-HEAVY_LAMBDA VH VH
IG-Light-Lambda V-LAMBDA V-LAMBDA

IMGT/PROTEIN-DB and IMGT/3Dstructure-DB keywords and labels: IG engineered

IDENTIFICATION Standardized labels for DESCRIPTION
Receptor type Chain type Receptor Chain Domain
Lambda-Lambda Lambda-Lambda LAMBDA-LAMBDA LAMBDA-LAMBDA V-LAMBDA, C-LAMBDA
scFv-Heavy-Kappa scFv-Heavy-Kappa SCFV-HEAVY-KAPPA SCFV-HEAVY-KAPPA VH, LINKER, V-KAPPA
scFv-Heavy-Lambda
(3)
scFv-Heavy-Lambda SCFV-HEAVY-LAMBDA SCFV-HEAVY-LAMBDA VH, LINKER, V-LAMBDA

IMGT/PROTEIN-DB and IMGT/3Dstructure-DB keywords and labels: TR engineered

IDENTIFICATION Standardized labels for DESCRIPTION
Receptor type Chain type Receptor Chain Domain
scFv-Alpha-Beta scFv-Alpha-Beta SCFV-ALPHA-BETA SCFV-ALPHA-BETA V-ALPHA, LINKER, V-BETA
scFv-Gamma-Delta scFv-Gamma-Delta SCFV-GAMMA-DELTA SCFV-GAMMA-DELTA V-GAMMA, LINKER, V-DELTA

IMGT/PROTEIN-DB and IMGT/3Dstructure-DB keywords and labels: MH engineered

IDENTIFICATION Standardized labels for DESCRIPTION
Receptor type Chain type Receptor Chain Domain
MH2-peptide MH2-Alpha MH2-ALPHA_BETA-PEPTIDE MH2-ALPHA G-ALPHA, C-LIKE
MH2-Beta-peptide MH2-BETA-PEPTIDE G-BETA, LINKER, PEPTIDE, C-LIKE

IMGT/PROTEIN-DB and IMGT/3Dstructure-DB keywords and labels: FPIA engineered

FPIA comprise proteins with the suffix -cept in the INN nomenclature. Recent entries are available in IMGT/2Dstructure-DB.

IDENTIFICATION Standardized labels for DESCRIPTION
Receptor type Chain type Receptor Chain Domain and Region
Fusion-Fc-Gamma1 Fusion-Gamma1 FUSION-FC-GAMMA-1 FUSION-GAMMA1 [D1], H, CH2, CH3
Fusion-Gamma1 FUSION-GAMMA1
Fusion-Fc-Gamma1 Fusion-Gamma1 FUSION-FC-GAMMA-1 FUSION-GAMMA1 [D1], [D2], H, CH2, CH3
Fusion-Gamma1 FUSION-GAMMA1
scFv-Kappa-Heavy-Toxin scFv-Kappa-Heavy-Toxin SCFV-KAPPA-HEAVY-TOXIN SCFV-KAPPA-HEAVY-TOXIN V-KAPPA, LINKER, VH, TOXIN
IgM_Kappa_J-chain IG-Heavy-Mu IG-MU_KAPPA_J-CHAIN H-MU VH, CH1, CH2, CH3, CH4
IG_Light_Kappa L-KAPPA V-KAPPA, C-KAPPA
J-chain J-CHAIN J-CHAIN
IMGT notes:
(1) For polymeric IgM or IgA for which the J chain is described, the letter "J" (for J-CHAIN) is added to the receptor description label. For example, IG-MU_KAPPA_J.
(2) A complete chain description also uses the following IMGT/LIGM-DB labels: HINGE-REGION, CONNECTING-REGION, TRANSMEMBRANE-REGION, CYTOPLASMIC-REGION and CHS. HINGE-REGION is present in IG heavy chains, except H-MU and H-EPSILON.
(3) There are several IG-Light-Lambda chains (not shown in this table). If the isotype is known, a hyphen and a number are added. Example: IgG1-Lambda-1 (receptor type) and IG-Light-Lambda-1 (chain type) for the receptor and chain 'IDENTIFICATION'.
IG-GAMMA-1_LAMBDA-1 (receptor), L-LAMBDA-1 (chain) and C-LAMBDA-1 (domain) for the receptor and chain 'DESCRIPTION'.
(4) MH and MhSF proteins which possess C-LIKE domain belong also to the IgSF superfamily.
(5) RPI-MH1Like may or may not comprise B2M. For those without B2M, C-LIKE of the MH1LIKE-ALPHA chain may be absent.
Examples of MH1LIKE-ALPHA_B2M: CD1A to CD1E, FCGRT (FcRn), HFE, MR1.
Examples of MH1LIKE-ALPHA (without B2M) with C-LIKE: MICA pdf, MICB, AZGP1, without C-LIKE:PROCR (EPCR), RAE, TE1, RAETG and RAETIL.
(6) For Fab, (Fab')2 and Fc, the chain type (IDENTIFICATION) does not tacke into account the fact that the heavy chain is partial. See standardized labels for DESCRIPTION for a description of the chains.