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3D structure of an IgG immunoglobulin

The 3D structure is from 1igt in IMGT/3Dstructure-DB.

VH: V-DOMAIN of the immunoglobulin heavy chain
VL: V-DOMAIN of the immunoglobulin light chain
CH1, CH2, CH3: C-DOMAIN of the immunoglobulin heavy chain
CL: C-DOMAIN of the immunoglobulin light chain

VH corresponds to the V-D-J-REGION (in green (V), orange (DJ)) of the heavy chain.
VL corresponds to the V-J-REGION (in green (V) and yellow (J)) of the light chain.
Click here for a Schematic representation of an immunoglobulin.

The first crystal 3D structure of a complete human immunoglobulin is that of b12, a human IgG1, anti-gp120 [HIV-1], determined in 2001 (PDB code: 1hzh in IMGT/3Dstructure-DB).

Archive: Spacefill 3D representation of an IgG model

Created: 28/06/2001
Last updated: Friday, 22-Sep-2023 18:15:57 CEST
Author: Marie-Paule Lefranc Marie-Paule.Lefranc@igh.cnrs.fr
Editors: Elodie Foulquier, Chantal Ginestoux