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IgG1 proteolytic cleavage by the papain gives two Fab
fragments and a Fc (Fragment cristallizable) fragment.
Fc fragment is composed of two identical, disulfide-linked peptides containing the
heavy chain CH2 and CH3 domains.
Created: 28/06/2001
Last updated: Thursday, 07-Aug-2025 21:00:49 CEST
Author: Marie-Paule Lefranc
Marie-Paule.Lefranc@igh.cnrs.fr
Editors: Elodie Foulquier, Chantal Ginestoux