IMGT Web resources: IMGT repertoire

3D representation: Mouse (Mus musculus) two associated V-DOMAINs from D1.3Fv (PDB: 1dvf_A and 1dvf_B)

IMGT/3Dstructure-DB card: 1dvf

Side view (backbone model)

V-DOMAIN
VH
IGH
V-D-J-REGION
(PDB: 1dvf_B)

V-DOMAIN
V-KAPPA
IGK
V-J-REGION
(PDB: 1dvf_A)

A V-DOMAIN corresponds to the V-J-REGION or V-D-J-REGION of the immunoglobulin and T cell receptor chains.
This figure shows the two associated V-DOMAINs isolated from an antibody and constituting what is called a "Fv" (for "fragment variable")

Legend:

CDR-IMGT regions are colored according to the IMGT color menu:
IGK V-J-REGION: CDR1-IMGT (blue), CDR2-IMGT (green), CDR3-IMGT (dark green)
IGH V-D-J-REGION: CDR1-IMGT (red), CDR2-IMGT (orange), CDR3-IMGT (purple).
V-DOMAIN strands are colored according to the IMGT color menu for strand representation: A, B and C strands (orange), C' and C'' strands (green), D strand (yellow), E, F and G strands (blue).
This image has been generated with the program RASMOL version 2.6 from the PDB file 1dvf, containing the atomic coordinates of the complex between Idiotope D1.3 -anti-idiotope E5.2. Both D1.3 (1dvf_A, 1dvf_B) and E5.2 (1dvf_C, 1dvf_D) are mouse antibodies (Mus musculus) IgG1, kappa. Only the D1.3 Fv is displayed here.

See also:

DOMAIN in IMGT Index

IMGT 2D and 3D representations (examples) in IMGT Repertoire.

Created: 11/06/2001
Last updated: Friday, 22-Sep-2023 18:17:03 CEST
Author: Marie-Paule Lefranc Marie-Paule.Lefranc@igh.cnrs.fr
Editors: Elodie Foulquier and Marie-Paule Lefranc