3D structures
Collier de Perles: Human IGH V-D-J-REGION from Fab-12 (PDB: 1cz8)
IMGT/3Dstructure-DB card: 1cz8
[8.8.16]
Legend
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Amino acids are shown in the one-letter abbreviation.
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Hydrophobic amino acids (hydropathy index with positive value) and Tryptophan (W) found at a given position in more than 50 % of analysed Ig and TcR sequences are shown in blue.
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All Proline (P) are shown in yellow.
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The CDR-IMGT are limited by amino acids shown in squares, which belong to the neighbouring FR-IMGT. The CDR3-IMGT extend from position 105 to the position preceding J-PHE or J-TRP.
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Hachured circles or squares correspond to missing positions according to the IMGT unique numbering.
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Arrows indicate the direction of the beta sheets and their different designations in 3D structure. This information has to be used carefully if not supported by experimental data.
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CDR-IMGT regions are colored as follows:
CDR1-IMGT (red), CDR2-IMGT (orange), CDR3-IMGT (purple)
Created: 11/06/2001
Author: Manuel Ruiz
