3D structures
Collier de Perles: Human IGH V-D-J-REGION from M3C65 (PDB: 1dl7)
IMGT/3Dstructure-DB card: 1dl7
[8.7.7]
Legend
-
Amino acids are shown in the one-letter abbreviation.
-
Hydrophobic amino acids (hydropathy index with positive value) and Tryptophan (W) found at a given position in more than 50 % of analysed Ig and TcR sequences are shown in blue.
-
All Proline (P) are shown in yellow.
-
The CDR-IMGT are limited by amino acids shown in squares, which belong to the neighbouring FR-IMGT. The CDR3-IMGT extend from position 105 to the position preceding J-PHE or J-TRP.
-
Hachured circles or squares correspond to missing positions according to the IMGT unique numbering.
-
Arrows indicate the direction of the beta sheets and their different designations in 3D structure. This information has to be used carefully if not supported by experimental data.
-
CDR-IMGT regions are colored as follows:
CDR1-IMGT (red), CDR2-IMGT (orange), CDR3-IMGT (purple)
Created: 11/06/2001
Author: Manuel Ruiz
