An asterisk (*) indicates a longer N-terminal end as
predicted by the program SIGSEQ2 [Wülfing and Plückthun, Immunology Today, 16, 405-406 (1995)].
TRAV genes
|
FR1-IMGT 1 to 26 |
CDR1-IMGT 27 to 38 |
FR2-IMGT 39 to 55 |
CDR2-IMGT 56 to 65 |
FR3-IMGT
66 to 104 |
CDR3-IMGT
(germline V-GENE)
105 to 115 |
(25,26,32,34) |
(5 to 7) |
(16,17) |
(3 to 7) |
(33 to 35) |
(2 to 5) |
TRAV1-1 ,
TRAV1-2 |
-1 (aa 7)
|
6 |
|
5
|
-7 (aa 71 to 77) +3 (aa 84A,84B,84C) |
3 |
TRAV2 |
-1 (aa 7)
|
6
|
|
3 |
-7 (aa 71 to 77) +1 (aa 84A) |
3 |
TRAV3 |
|
6 |
|
7 |
-7 (aa 71 to 77) +3 (aa 84A,84B,84C) |
4 |
TRAV4 |
-1 (aa 7) |
7 |
|
4 |
-7 (aa 71 to 77) +3 (aa 84A,84B,84C) |
4 |
TRAV5 |
-1 (aa 8)
|
6 |
|
6 |
-7 (aa 71 to 77) +3 (aa 84A,84B,84C) |
3 |
TRAV6 |
|
6 |
|
6 |
-7 (aa 71 to 77) +3 (aa 84A,84B,84C) |
3 |
TRAV7 |
|
6 |
|
6 |
-7 (aa 71 to 77) +1 (aa 84A) |
3 |
TRAV8-1 to TRAV8-4
TRAV8-6,
TRAV8-7 |
|
6
6
6
|
|
7
7
7 |
-7 (aa 71 to 77) +3 (aa 84A,84B,84C)
-7 (aa 71 to 77) +3 (aa 84A,84B,84C)
-7 (aa 71 to 77) +3 (aa 84A,84B,84C) |
3
3
5 |
TRAV9-1,
TRAV9-2 |
|
6 |
|
6 |
-7 (aa 71 to 77) +3 (aa 84A,84B,84C) |
3 |
TRAV10 |
|
6 |
|
6 |
-7 (aa 71 to 77) +3 (aa 84A,84B,84C) |
3 |
TRAV11 |
|
6 |
|
6 |
-7 (aa 71 to 77) +3 (aa 84A,84B,84C) |
2 |
TRAV12-1,
TRAV12-2,
TRAV12-3 |
|
6
6
6 |
|
5
5
5 |
-1 (aa 67) -7 (aa 71 to 77) +3 (aa 84A,84B,84C)
-7 (aa 71 to 77) +3 (aa 84A,84B,84C)
-7 (aa 71 to 77) +3 (aa 84A,84B,84C) |
3
3
3 |
TRAV13-1,
TRAV13-2 |
|
6 |
|
6 |
-7 (aa 71 to 77) +3 (aa 84A,84B,84C) |
3 |
TRAV14/DV4 |
|
7 |
|
7 |
-7 (aa 71 to 77) +3 (aa 84A,84B,84C) |
4 |
TRAV16 |
|
6 |
|
3 |
-7 (aa 71 to 77) +3 (aa 84A,84B,84C) |
3 |
TRAV17 |
|
5 |
|
6 |
-7 (aa 71 to 77) +3 (aa 84A,84B,84C) |
3 |
TRAV18 |
|
6 |
|
5 |
-7 (aa 71 to 77) +3 (aa 84A,84B,84C) |
3 |
TRAV19 |
|
7 |
|
7 |
-7 (aa 71 to 77) +3 (aa 84A,84B,84C) |
4 |
TRAV20 |
|
6 |
|
6 |
-7 (aa 71 to 77) +1 (aa 84A) |
3 |
TRAV21 |
|
6 |
|
6 |
-7 (aa 71 to 77) +3 (aa 84A,84B,84C) |
3 |
TRAV22 |
|
5 |
|
4 |
-7 (aa 71 to 77) +3 (aa 84A,84B,84C) |
3 |
TRAV23/DV6 |
+8 aa in 5'* |
6 |
|
6 |
-7 (aa 71 to 77) +3 (aa 84A,84B,84C) |
3 |
TRAV24 |
|
6 |
|
6 |
-7 (aa 71 to 77) +3 (aa 84A,84B,84C) |
2 |
TRAV25 |
|
5 |
|
6 |
-7 (aa 71 to 77) +3 (aa 84A,84B,84C) |
2 |
TRAV26-1,
TRAV26-2 |
-1 (aa 7) |
7 |
|
4 |
-7 (aa 71 to 77) +3 (aa 84A,84B,84C) |
4 |
TRAV27 |
|
5 |
|
6 |
-7 (aa 71 to 77) +3 (aa 84A,84B,84C) |
2 |
TRAV29/DV5 |
+6 aa in 5'* |
6 |
|
6 |
-7 (aa 71 to 77) +3 (aa 84A,84B,84C) |
3 |
TRAV30 |
-1 (aa 5) |
5 |
|
6 |
-7 (aa 71 to 77) +3 (aa 84A,84B,84C) |
3 |
TRAV34 |
|
5 |
|
6 |
-7 (aa 71 to 77) +3 (aa 84A,84B,84C) |
3 |
TRAV35 |
|
5 |
|
6 |
-7 (aa 71 to 77) +3 (aa 84A,84B,84C) |
3 |
TRAV36/DV7 |
|
6
|
-1 (aa 50)
|
6
|
-7 (aa 71 to 77) +3 (aa 84A,84B,84C)
|
3
|
TRAV38-1,
TRAV38-2/DV8 |
|
7 |
|
7 |
-7 (aa 71 to 77) +3 (aa 84A,84B,84C) |
4 |
TRAV39 |
|
5 |
|
6 |
-7 (aa 71 to 77) +3 (aa 84A,84B,84C) |
3 |
TRAV40 |
-1 (aa 8) |
6 |
|
3 |
-7 (aa 71 to 77) +1 (aa 84A) |
3 |
TRAV41 |
|
5 |
|
4 |
-7 (aa 71 to 77) +3 (aa 84A,84B,84C) |
3 |