TRBV genes are designated according to IMGT gene tables and Locus representations.
Only FUNCTIONAL and ORF V-GENEs are shown.
The proteolytic cleavage site between the leader peptide and the V-REGION is putative and the assignment of amino acid 1 to one or the other region is uncertain.
TRBV
genes (1) |
FR1-IMGT
1 to 26 |
CDR1-IMGT
27 to 38 |
FR2-IMGT
39 to 55 |
CDR2-IMGT
56 to 65 |
FR3-IMGT
66 to 104 |
CDR3-IMGT
(germline V-GENE) 105 to 115 |
(25,26) | (5,6) | (17) | (5 to 7) | (36 to 38) | (3,4) | |
TRBV1 | 6 | 6 | -3 (aa 82,96,97) | 4 | ||
TRBV2 | 5 | 6 | -2 (aa 73,82) | 4 | ||
TRBV3 | 5 | 6 | -1 (aa 82) | 4 | ||
TRBV4 | 5 | 6 | -2 (aa 73,82) | 3 | ||
TRBV5 |
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TRBV12-1
TRBV12-2 |
5 | 6 | -2 (aa 73,82) | 4 | ||
TRBV13-1
TRBV13-2 TRBV13-3 |
5 | 6 | -2 (aa 73,82) | 4 | ||
TRBV14 |
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TRBV15 | 5 | 6 | -1 (aa 82) | 4 | ||
TRBV16 | 5 | 6 | -1 (aa 82) | 4 | ||
TRBV17 | 5 | 6 | -2 (aa 73,82) | 4 | ||
TRBV19 | 5 | 6 | -2 (aa 73,82) | 4 | ||
TRBV20 | 6 | 7 | -1 (aa 82) | 3 | ||
TRBV21 | 5 | 6 | -1 (aa 82) | 4 | ||
TRBV23 | 5 | 6 | -1 (aa 82) | 4 | ||
TRBV24 | 5 | 6 | -1 (aa 82) | 4 | ||
TRBV26 | 5 | 6 | -1 (aa 82) | 4 | ||
TRBV29 | 5 | 6 | -2 (aa 73,82) | 4 | ||
TRBV30 | 5 | 7 | -1 (aa 82) | 3 | ||
TRBV31 | 6 | 5 | -2 (aa 73,82) | 3 |
IMGT Note:
(1) | The TRBV6, TRBV7, TRBV8, TRBV9, TRBV10, TRBV11, TRBV18, TRBV22, TRBV25, TRBV27, TRBV28 genes, single members of their subgroups, and TRBV12-3 gene, are not shown, being pseudogenes. |
Created: 26/10/1999
Author: Nathalie Bosc