Humanized antibodies
Collier de Perles: Human Rei ("acceptor" sequence) IGK V-J REGION
Collier de Perles: Norway rat CAMPATH-1G (YTH34.5HL) ("donor" sequence)
Collier de Perles: Humanized CAMPATH-1H (HuVLCAMP)
Human Rei ("acceptor" sequence) IGK V-J REGION
CDR-IMGT lengths [6.3.9]
Legend:
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Human amino acids are shown in red.
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Amino acids are shown in the one-letter abbreviation.
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Hydrophobic amino acids (hydropathy index with positive value) and Tryptophan (W) found at a given position in more than 50 % of analysed IG and TR sequences are shown in blue.
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All Proline (P) are shown in yellow.
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The CDR-IMGT are limited by amino acids shown in squares, which belong to the neighbouring FR-IMGT.
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Hachured circles or squares correspond to missing positions according to the IMGT unique numbering.
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Arrows indicate the direction of the beta sheets and their different designations in 3D structure.
This information has to be used carefully if not supported by experimental data.
Created: 07/06/2001
Last updated: Friday, 22-Sep-2023 18:17:56 CEST
Author: Lisa Truong and Fatena Bellahcene