Translocations and inversions: Human TRA

Click here to see Part 2 - Inversions involving the TRA locus

Part 1 - Translocations involving the TRA locus

Locus Chromosomal localization Translocation Other involved genes (1) Clinical entities (2)
TRA 14q11.2 t(1;14)(p32;q11) TAL1 T cell acute lymphoblastic leukemia (T-ALL)
t(8;14)(q24;q11) MYC T cell acute lymphoblastic leukemia (T-ALL)
t(10;14)(q24;q11) TLX1 T cell acute lymphoblastic leukemia (T-ALL)
non-Hodgkin lymphoma (NHL)
t(11;14)(p13;q11) LMO2 T cell acute lymphoblastic leukemia (T-ALL)
t(14;14)(q11;q32) TCL1A T cell chronic lymphocytic leukemia (T-CLL)
T cell prolymphocytic leukemia (T-PLL)
t(14;21)(q11;q22) unknown (21q22) T cell acute lymphoblastic leukemia (T-ALL)
t(X;14)(q28;q11) MTCP1 T prolymphocytic leukemia

IMGT notes:
(1) For the list of genes (other than IG or TR) involved in the translocations, click here.
(2) Information on clinical entities are from the literature and from the Atlas of Genetics and Cytogenetics in Oncology and Haematology. For a list of the clinical entities quoted in the translocation tables, click here.

Part 2 - Inversions involving the human TRA locus

Locus Chromosomal localization Inversion Other involved genes Clinical entities
TRA 14q11.2 inv(14)(q11;q32) IGH T cell lymphoma
TCL1A T cell prolymphocytic leukemia (T-PLL)
T cell acute lymphoblastic leukemia (T-ALL)

Created: 29/03/2001
Last updated: Friday, 22-Sep-2023 18:17:58 CEST
Author: Marie-Paule Lefranc
Editors: Sandrine Béranger and Céline Protat