Translocations and inversions: Human TRB

Click here to see Part 2 - Inversions involving the TRB locus

Part 1 - Translocations involving the TRB locus

Locus Chromosomal localization Translocation Other involved genes (1) Clinical entities (2)
TRB 7q34 t(1;7)(p32;q34) TAL1 T cell acute lymphoblastic leukemia (T-ALL)
t(1;7)(p34;q34) LCK T cell acute lymphoblastic leukemia (T-ALL)
t(7;9)(q34;q32) TAL2 T cell acute lymphoblastic leukemia (T-ALL)
t(7;9)(q34;q34) NOTCH1 T cell acute lymphoblastic leukemia (T-ALL)
t(7;10)(q34;q24) TLX1 T cell acute lymphoblastic leukemia (T-ALL)
non-Hodgkin lymphomia (NHL)
t(7;11)(q34;p13) LMO2 T cell acute lymphoblastic leukemia (T-ALL)
t(7;19)(q34;p13) LYL1 T cell acute lymphoblastic leukemia (T-ALL)

IMGT notes:
(1) For the list of genes (other than IG or TR) involved in the translocations, click here.
(2) Information on clinical entities are from the literature and from the Atlas of Genetics and Cytogenetics in Oncology and Haematology. For a list of the clinical entities quoted in the translocation tables, click here.

Part 2 - Inversions involving the TRB locus

Locus Chromosomal localization Inversion Other involved genes Clinical entities
TRB 7q34 inv(7)(p14;q34) TRG Ataxia telangiectasis
Leukemia

Created: 23/11/2000
Last updated: 02/10/2025 13:10
Author: Marie-Paule Lefranc
Editors: Sandrine Béranger and Céline Protat