Translocations and inversions: Human TRD

Click here to see Part 2 - Inversions involving the TRD locus

Part 1 - Translocations involving the TRD locus

Locus Chromosomal localization Translocation Other involved genes (1) Clinical entities (2)
TRD 14q11.2 t(1;14)(p32;q11) TAL1 T cell acute lymphoblastic leukemia (T-ALL)
t(8;14)(q24;q11) MYC T cell acute lymphoblastic leukemia (T-ALL)
t(10;14)(q24;q11) TLX1 T cell acute lymphoblastic leukemia (T-ALL)
non-Hodgkin lymphoma (NHL)
t(11;14)(p13;q11) LMO2 T cell acute lymphoblastic leukemia (T-ALL)
t(11;14)(p15;q11) LMO1 T cell acute lymphoblastic leukemia (T-ALL)
t(14;14)(q11;q32) TCL1A T cell chronic lymphocytic leukemia (T-CLL)
T cell prolymphocytic leukemia (T-PLL)

IMGT notes:
(1) For the list of genes (other than IG or TR) involved in the translocations, click here.
(2) Information on clinical entities are from the literature and from the Atlas of Genetics and Cytogenetics in Oncology and Haematology. For a list of the clinical entities quoted in the translocation tables, click here.

Part 2 - Inversions involving the TRD locus

Locus Chromosomal localization Inversion Other involved genes Clinical entities
TRD 14q11.2 inv(14)(q11;q32) TCL1A T cell prolymphocytic leukemia (T-PLL)
T cell acute lymphoblastic leukemia (T-ALL)

Created: 29/03/2001
Last updated: Friday, 22-Sep-2023 18:17:58 CEST
Author: Marie-Paule Lefranc
Editors: Sandrine Béranger and Céline Protat