IGHC gene
and
allele name
(1)
5' exon 3' exon codon_start
Exons Last
complete
codon (2)
Codon
resulting
from
splicing
First
complete
codon (2)
Exons
IGHA*01 (3)   (E) 1.3
S
TCT
CH1 3
G AG
CH1 97
S
TCT
(G) 2
P
CCT
H+CH2 3
G GT
H+CH2 99
T
ACA
(V) 1.3
N
AAC
CH3 3
G TG
CH3 (4) 107
S
TCG
(E) 1
R
CGT
M 3
G AA
IGHD*01 (3)   (G) 1.3
D
GAT
CH1 3
G GT
CH1 90
P
CCT
(E) 2
S
TCA
H 3
G AG
H 35
E
GAA
(G) 1.2
A
GCC
CH3 3
G GG
CH3 104
S
AGT
G (G)
GA
2
C
TGC
CHS 3
(G)
GC
1.1
I
ATA
M1
M1 51
K
AAG
  1
V
GTG
M2 1
IGHE*01 (3)   (A) 1.3
S
TCT
CH1 3
G CC
CH1 88
L
CTA
(V) 1.6
R
CGA
CH2 3
G TT
CH2 100
P
CCA
(D) 1.4
H
CAT
CH3 3
G AT
CH3 102
P
CCA
(G) 1.3
Q
CAG
CH4 3
G GC
CH4 (4) 105
L
CTT
(E) 8
L
CTA
M1 3
G AG
M1 51
K
AAG
  1
V
GTG
M2 1
IGHG1*01 (3)   (A) 1.3
K
AAA
CH1 3
G CC
CH1 93
I
ATT
(V) 2
P
CCC
H 3
G TG
H 13
T
ACA
(V) 1.2
P
CCA
CH2 3
G TC
CH2 109
K
AAA
(G) 1.3
R
AGA
CH3 3
G GC
CH3 (4) 101
P
CCT
(G) 9
L
CTG
M1 3
G GG
M1 51
K
AAG
  1
V
GTA
M2 1
IGHG2A*01 (3)   (A) 1.3
K
AAA
CH1 3
G CC
CH1 93
I
ATT
(E) 2
P
CCC
H 3
G AG
H 16
P
CCA
(A) 1.5
P
CCT
CH2 3
G CA
CH2 109
K
AAA
(G) 1.3
S
TCA
CH3 3
G GG
CH3 (4) 101
P
CCG
(G) 9
L
CTA
M1 3
G GG
M1 51
K
AAG
  1
V
GTA
M2 1
IGHG2B*01 (3)   (A) 1.3
K
AAA
CH1 3
G CC
CH1 93
L
CTT
(E) 2
P
CCC
H 3
G AG
H 22
P
CCA
(A) 1.5
P
CCT
CH2 3
G CT
CH2 109
K
AAA
(G) 1.3
L
CTA
CH3 3
G GG
CH3 (4) 101
P
CCG
(G) 9
L
CTA
M1 3
G GG
M1 51
K
AAG
  1
V
GTA
M2 1
IGHG2C*01 (3)   (A) 1.3
K
AAA
CH1 3
G CC
CH1 93
I
AAT
(E) 2
P
CCC
H 3
G AG
H 21
A
GCA
(A) 1.5
P
CCA
CH2 3
G CT
CH2 109
R
AGA
(G) 1.3
P
CCA
CH3 3
G GG
CH3 (4) 101
L
CTG
(G) 9
L
CTA (5)
M1 3
G GG (5)
M1 51
K
AAG (5)
  1
V
GTA (5)
M2 1
IGHG3*01 (3)   (A) 1.3
T
ACA
CH1 3
G CT
CH1 93
I
ATC
(E) 2
P
CCT
H 3
G AG
H 16
P
CCA
(P) 1.5
G
GGT
CH2 3
C CT
CH2 109
K
AAA
(G) 1.3
R
AGA
CH3 3
G GA
CH3 (4) 101
P
CCT
(E) 9
L
CTG
M1 3
G AG
M1 51
K
AAG
  1
V
GTG
M2 1
IGHM*01 (3)   (E) 1.3
S
AGT
CH1 3
G AG
CH1 100
P
CCA
(A) 1.4
V
GTC
CH2 3
G CT
CH2 107
A
GCC
(S) 1.3
P
CCC
CH3 3
A GT
CH3 102
N
AAT
(E) 1.4
V
GTG
CH4 3
G AG
CH4 (4) 106
T
ACT
(E) 14
G
GGG
M1 3
G AG
M1 51
K
AAG
  1
V
GTG
M2 1
More information:
  1. Gene and allele table: Mouse (Mus musculus) IGHC
  2. Protein display: Mouse (Mus musculus) IGH C-REGIONs
IMGT notes:
(1) Only allele *01 is shown.
(2) Position of the last complete codon of the 5' exon and that of the first complete codon of the 3' exon are according to the IMGT unique numbering for C-DOMAIN and C-LIKE-DOMAIN.
(3) The last nucleotide G of the IGH J-REGION, part of the codon resulting from the splicing with CH1, is indicated for each IGHC gene.
(4) The donor splice of the 5' exon is an internal donor splice (INT-DONOR-SPLICE) involved in the splicing of the IGH membrane chain transcript. Synthesis of a membrane and of a secreted immunoglobulin mu heavy chain (IMGT Education)
(5) Defined by homology with the other IGHG2 genes. Needs to be confirmed by sequencing.