The pig IGL locus is located on the chromosome 14, at band 14q16-q21.
The potential genomic IGL repertoire comprises 21 IGLV genes belonging to 7 subgroups (10 functional, 2 ORF and 9 pseudogene), 3 functional IGLJ genes and 2 functional IGLC genes [1].
IGLV genes
Subgroup | Functional | ORF | Pseudogene | Total |
IGLV1 | - | - | 2 | 2 |
IGLV2 | 1 | - | - | 1 |
IGLV3 | 4 | - | 1 | 5 |
IGLV5 | 1 | - | 3 | 4 |
IGLV7 | - | 2 | - | 2 |
IGLV8 | 4 | - | 2 | 6 |
IGLV(III) | - | - | 1 | 1 |
Total | 10 | 2 | 9 | 21 |
IGLJ genes
Gene | Functional | ORF | Pseudogene | Total |
IGLJ2 | 1 | - | - | 1 |
IGLJ3 | 1 | - | - | 1 |
IGLJ4 | 1 | - | - | 1 |
Total | 3 | - | - | 3 |
IGLC genes
Gene | Functional | ORF | Pseudogene | Total |
IGLC2 | 1 | - | - | 1 |
IGLC3 | 1 | - | - | 1 |
Total | 2 | - | - | 2 |
IMGT references:
[1] Schwartz J.C. et al., Immunogenetics, 64, 399-407 (2012). PMID: 22186825