Rabbit (Oryctolagus cuniculus) TRBV genes
The rabbit (
Oryctolagus cuniculus) TRB locus comprises 77 TRBV genes belonging to 26 TRBV subgroups:
The TRBV genes are localized in 2 V-CLUSTER:
- the 5' V-CLUSTER, classically in 5' of the TRBD, TRBJ and TRBC, includes 76 TRBV genes belonging to 25 subgroups (58-59 genes are functional and 17-18 genes are pseudogenes)
- the 3' V-CLUSTER, downstream of the TRBC in inverted orientation, includes 1 TRBV gene (functional)
| Localization of the V-CLUSTER in the locus |
IMGT subgroup |
Functional |
ORF |
Pseudogene |
Total |
| 5' V-CLUSTER |
TRBV1 |
1 |
0 |
0 |
1 |
| TRBV2 |
1(+1)* |
0 |
(1 (0:1))* |
2 |
| TRBV3 |
1 |
0 |
0 |
1 |
| TRBV4 |
1 |
0 |
0 |
1 |
| TRBV5 |
13 |
0 |
4 (1:3) |
17 |
| TRBV6 |
13 |
0 |
1 (0:1) |
14 |
| TRBV7 |
9 |
0 |
5 (2:3) |
14 |
| TRBV9 |
0 |
0 |
2 (0:2) |
2 |
| TRBV10 |
1 |
0 |
0 |
1 |
| TRBV12 |
1 |
0 |
0 |
1 |
| TRBV13 |
1 |
0 |
0 |
1 |
| TRBV15 |
0 |
0 |
1 (0:1) |
1 |
| TRBV16 |
0 |
0 |
1 (0:1) |
1 |
| TRBV17 |
0 |
0 |
1 (0:1) |
1 |
| TRBV18 |
1 |
0 |
0 |
1 |
| TRBV19 |
1 |
0 |
0 |
1 |
| TRBV20 |
2 |
0 |
0 |
2 |
| TRBV21 |
7 |
0 |
0 |
7 |
| TRBV23 |
0 |
0 |
1 (0:1) |
1 |
| TRBV24 |
0 |
0 |
1 (0:1) |
1 |
| TRBV25 |
1 |
0 |
0 |
1 |
| TRBV26 |
1 |
0 |
0 |
1 |
| TRBV27 |
1 |
0 |
0 |
1 |
| TRBV28 |
1 |
0 |
0 |
1 |
| TRBV29 |
1 |
0 |
0 |
1 |
| 3' V-CLUSTER |
TRBV30 |
1 |
0 |
0 |
1 |
| Total |
59(+1)* |
0 |
17(+1)* |
77 |
In the column 'Pseudogene', the number of pseudogenes with V-REGION in-frame and the number of pseudogenes with frameshift(s) are shown separated by two dots, between parentheses.
* An asterisk indicates that the following genes have alleles with different functionalities:
FUNCTIONAL or PSEUDOGENE (TRBV2-2).
Rabbit (Oryctolagus cuniculus) TRBD genes
The rabbit (
Oryctolagus cuniculus) TRB locus comprises 2 TRBD genes belonging to 2 TRBD set:
| IMGT group |
IMGT set or subgroup (if any) |
Functional |
ORF |
Pseudogene |
Total |
| TRBD |
TRBD1 |
1 |
0 |
0 |
1 |
| TRBD2 |
1 |
0 |
0 |
1 |
| Total |
2 |
0 |
0 |
2 |
Rabbit (Oryctolagus cuniculus) TRBJ genes
The rabbit (
Oryctolagus cuniculus) TRB locus comprises 12 TRBJ genes belonging to 2 TRBJ set:
| IMGT group |
IMGT set or subgroup (if any) |
Functional |
ORF |
Pseudogene |
Total |
| TRBJ |
TRBJ1 |
5 |
1 |
0 |
6 |
| TRBJ2 |
6 |
0 |
0 |
6 |
| Total |
11 |
1 |
0 |
12 |
More information:
Gene table: rabbit (Oryctolagus cuniculus) TRBV
Gene table: rabbit (Oryctolagus cuniculus) TRBD
Gene table: rabbit (Oryctolagus cuniculus) TRBJ
Locus description: rabbit (Oryctolagus cuniculus) TRB