Western lowland gorilla (Gorilla gorilla gorilla) IGHV genes

The Western lowland gorilla (Gorilla gorilla gorilla) IGH locus on chromosome 14 comprises 151 IGHV genes belonging to 8 IGHV subgroups :
IMGT group IMGT subgroup Functional ORF Pseudogene Total
IGHV IGHV1 4 (+2)* 1 9-6** (4:5)1 (+2 (0:2))* 16
IGHV2 1 (+1)* 1 2-1** (1:1) (+1 (0:1))* 5
IGHV3 16 (+10)* (+2)* 29-26** (13:16)1 (+8 (2:6))* 55
IGHV4 8 (+2)* 1 3-1** (0:3) (+2 (0:2))* 14
IGHV5 0 1 1 (0:1) 2
IGHV6 1 0 0 1
IGHV7 1** (+1)* 1 4 (0:4) (+1 (0:1))* 7
IGHV8 0 0 1 (1:0) 1
IGHV(II) 0 0 32-29** (0:32) 32
IGHV(III) 0 0 17-15** (0:17) 17
IGHV(IV) 0 0 1 (0:1) 1
Total 31 (+16)* 5 (+2) 99 (+14) 151
In the column 'Pseudogene', the number of pseudogenes with V-REGION in-frame and the number of pseudogenes with frameshift(s) are shown separated by two dots, between parentheses.
* An asterisk indicates that the following genes have alleles with different functionalities:
FUNCTIONAL or ORF (IGHV3-72, IGHV3-48).
FUNCTIONAL or PSEUDOGENE (IGHV1-8, IGHV1-69, IGHV2-70, IGHV3-7, IGHV3-9, IGHV3-13, IGHV3-15, IGHV3-20, IGHV3-30, IGHV3-43, IGHV3-62, IGHV4-30-2, IGHV4-30-6, IGHV7-4-1)
1 IGHV1-24, IGHV3-25, IGHV3-29, IGHV3-30-22, IGHV3-30-33, IGHV3-32 genes are PSEUDOGENE with different alleles in frame or out-of-frame. Only the functionality of alleles *01 are taken into account in this table.
** Two asterisks indicate allelic polymorphisms by insertion/deletion which concern:
- an insertion of 2 genes between IGHV2-70 and IGHV1-69 (IGHV1-69D and IGHV2-70D)
- an insertion of 5 genes between IGHV4-61 and IGHV(II)-60-1 (IGHV3-60-6, IGHV4-60-5, IGHV(II)-60-4, IGHV3-60-3, IGHV4-60-2)
- an insertion of 1 gene between IGHV3-23 and IGHV(II)-22-1 (IGHV(III)-22-2)
- an insertion of 4 genes between IGHV3-19 and IGHV(II)-15-1 (IGHV1-18, IGHV1-17, IGHV(III)-16-1, IGHV3-16)
- an insertion of 4 genes between IGHV7-4-1 and IGHV(II)-4-4 (IGHV(II)-4-8, IGHV(II)-4-7, IGHV4-4-6, IGHV7-4-5)
These insertions are found in the Susie3 assembly (IMGT000078 accession number) compared to the Kamilah_GGO_v0 assembly (IMGT000074 accession number)

Western lowland gorilla (Gorilla gorilla gorilla) IGHD genes

The Western lowland gorilla (Gorilla gorilla gorilla) IGH locus on chromosome 14 comprises 32 IGHD genes :
IMGT group IMGT set or subgroup (if any) Functional ORF Pseudogene Total
IGHD IGHD1 3-2** 3-1** 0 6
IGHD2 5-3** 0 0 5
IGHD3 4-2** (+1)* (+1)* 0 5
IGHD4 1 4-2** 0 5
IGHD5 3-1** 2 0 5
IGHD6 4-2** 0 1** 5
IGHD7 1 0 0 1
Total 21 (+1)* 9 (+1)* 1 32
* An asterisk indicates that the following gene has alleles with different functionalities:
FUNCTIONAL or ORF (IGHD3-16).
** Two asterisks indicate additional genes found in the Susie3 assembly (IMGT000078 accession number) compared to the Kamilah_GGO_v0 assembly (IMGT000074 accession number) where there is a gap at this position, these genes concern:
- 14 genes between IGHD5-5 and IGHD2-15 (IGHD6-5-1, IGHD1-5-2, IGHD2-5-3, IGHD3-5-4, IGHD4-5-5, IGHD5-5-6, IGHD6-6, IGHD1-7, IGHD2-8, IGHD3-10, IGHD4-11, IGHD5-12, IGHD6-13, IGHD1-14)


Western lowland gorilla (Gorilla gorilla gorilla) IGHJ genes

The Western lowland gorilla (Gorilla gorilla gorilla) IGH locus on chromosome 14 comprises 9 IGHJ genes :
IMGT group IMGT set or subgroup (if any) Functional ORF Pseudogene Total
IGHJ IGHJ1 1 0 0 1
IGHJ1P 0 0 1 1
IGHJ2 0 0 1** 1
IGHJ2P 0 1 0 1
IGHJ3 1 0 0 1
IGHJ3P 0 0 1 1
IGHJ4 1 0 0 1
IGHJ5 1 0 0 1
IGHJ6 1 0 0 1
Total 5 1 3 9
** Two asterisks indicate allelic polymorphisms by insertion/deletion which concern:
- an insertion of 1 gene between IGHJ1 and IGHJ2P (IGHJ2) in the Susie3 assembly (IMGT000078 accession number) compared to the Kamilah_GGO_v0 assembly (IMGT000074 accession number)

More information:
Gene table: Western lowland gorilla (Gorilla gorilla gorilla) IGHV
Gene table: Western lowland gorilla (Gorilla gorilla gorilla) IGHD
Gene table: Western lowland gorilla (Gorilla gorilla gorilla) IGHJ
Locus description: Western lowland gorilla (Gorilla gorilla gorilla) IGH