Western lowland gorilla (Gorilla gorilla gorilla) IGHV genes

The Western lowland gorilla (Gorilla gorilla gorilla) IGH locus on chromosome 14 comprises 157 IGHV genes belonging to 8 IGHV subgroups :
IMGT group IMGT subgroup Functional ORF Pseudogene Total
IGHV IGHV1 3 (+4)* 1 8-6** (3:5)1 (+4 (0:4))* 16
IGHV2 1 (+1)* 1 2-1** (1:1) (+1 (0:1))* 5
IGHV3 18 (+10)* (+3)* 30-25** (14:16)1 (+9 (2:7))* 59
IGHV4 8 (+5)* (+1) 1** (0:1) (+4 (0:4))* 14
IGHV5 0 1 1 (0:1) 2
IGHV6 1 0 0 1
IGHV7 1 (+1)* 1 4 (0:4) (+1 (0:1))* 7
IGHV8 0 0 1 (1:0) 1
IGHV(II) 0 0 35-29** (0:35) 35
IGHV(III) 0 0 16-15** (0:16) 16
IGHV(IV) 0 0 1 (0:1) 1
Total 32 (+21)* 4 (+4) 98 (+19) 157
In the column 'Pseudogene', the number of pseudogenes with V-REGION in-frame and the number of pseudogenes with frameshift(s) are shown separated by two dots, between parentheses.
* An asterisk indicates that the following genes have alleles with different functionalities:
FUNCTIONAL or ORF (IGHV4-4-6, IGHV3-72, IGHV3-48).
FUNCTIONAL or PSEUDOGENE (IGHV1-3, IGHV1-8, IGHV1-18, IGHV1-69, IGHV2-70, IGHV3-7, IGHV3-9, IGHV3-13, IGHV3-15, IGHV3-20, IGHV3-30, IGHV3-43, IGHV3-62, IGHV4-30-2, IGHV4-30-4, IGHV4-30-6, IGHV4-39D, IGHV4-60-2, IGHV7-4-1)
ORF or PSEUDOGENE (IGHV3-35).
1 IGHV1-24, IGHV1-68, IGHV3-25, IGHV3-29, IGHV3-30-22, IGHV3-30-33, IGHV3-32, IGHV7-34-1 genes are PSEUDOGENE with different alleles in frame or out-of-frame. Only the functionality of alleles *01 are taken into account in this table.
** Two asterisks indicate allelic polymorphisms by insertion/deletion which concern:
- an insertion of 2 genes between IGHV2-70 and IGHV1-69 (IGHV1-69D and IGHV2-70D)
- an insertion of 6 genes between IGHV1-67 and IGHV3-66 (IGHV3-66D, IGHV(II)-65-1D, IGHV3-65D, IGHV3-64D, IGHV3-63D and IGHV(II)-62-1D)
- an insertion of 5 genes between IGHV4-61 and IGHV(II)-60-1 (IGHV3-60-6, IGHV4-60-5, IGHV(II)-60-4, IGHV3-60-3, IGHV4-60-2)
- an insertion of 1 gene between IGHV3-23 and IGHV(II)-22-1 (IGHV(III)-22-2)
- an insertion of 4 genes between IGHV3-19 and IGHV(II)-15-1 (IGHV1-18, IGHV1-17, IGHV(III)-16-1, IGHV3-16)
- an insertion of 4 genes between IGHV7-4-1 and IGHV(II)-4-4 (IGHV(II)-4-8, IGHV(II)-4-7, IGHV4-4-6, IGHV7-4-5)
These insertions are found in the Susie3 assembly (IMGT000078 accession number), in the NHGRI_mGorGor1-v1.1-0.2.freeze_mat assembly (IMGT000139 accession number) and in the NHGRI_mGorGor1-v1.1-0.2.freeze_pat assembly (IMGT000140 accession number) compared to the Kamilah_GGO_v0 assembly (IMGT000074 accession number).

Western lowland gorilla (Gorilla gorilla gorilla) IGHD genes

The Western lowland gorilla (Gorilla gorilla gorilla) IGH locus on chromosome 14 comprises 32 IGHD genes belonging to 7 sets:
IMGT group IMGT set or subgroup (if any) Functional ORF Pseudogene Total
IGHD IGHD1 3-1** (+1)* 2-1** (+1)* 0 6
IGHD2 5-2** 0 0 5
IGHD3 5-2** 0 0 5
IGHD4 1 4-2** 0 5
IGHD5 3-2** 2 0 5
IGHD6 4-2** 0 1-1** 5
IGHD7 1 0 0 1
Total 22 (+1)* 8 (+1)* 1 32
* An asterisk indicates that the following gene has alleles with different functionalities:
FUNCTIONAL or ORF (IGHD1-5-2).
** Two asterisks indicate additional genes found in the Susie3 assembly (IMGT000078 accession number), in the NHGRI_mGorGor1-v1.1-0.2.freeze_mat assembly (IMGT000139 accession number) and in the NHGRI_mGorGor1-v1.1-0.2.freeze_pat assembly (IMGT000140 accession number) compared to the Kamilah_GGO_v0 assembly (IMGT000074 accession number) where there is a gap at this position, these genes concern:
- 14 genes between IGHD5-5 and IGHD2-15 (IGHD6-5-1, IGHD1-5-2, IGHD2-5-3, IGHD3-5-4, IGHD4-5-5, IGHD5-5-6, IGHD6-6, IGHD1-7, IGHD2-8, IGHD3-10, IGHD4-11, IGHD5-12, IGHD6-13, IGHD1-14)


Western lowland gorilla (Gorilla gorilla gorilla) IGHJ genes

The Western lowland gorilla (Gorilla gorilla gorilla) IGH locus on chromosome 14 comprises 9 IGHJ genes :
IMGT group IMGT set or subgroup (if any) Functional ORF Pseudogene Total
IGHJ IGHJ1 1 0 0 1
IGHJ1P 0 0 1 1
IGHJ2 0 (+1)** (+1)** 1
IGHJ2P 0 1 0 1
IGHJ3 1 0 0 1
IGHJ3P 0 0 1 1
IGHJ4 1 0 0 1
IGHJ5 1 0 0 1
IGHJ6 1 0 0 1
Total 5 1 (+1)* 2 (+1)* 9
** Two asterisks indicate allelic polymorphisms by insertion/deletion which concern:
- an insertion of 1 gene between IGHJ1 and IGHJ2P (IGHJ2) in the Susie3 assembly (IMGT000078 accession number), in the NHGRI_mGorGor1-v1.1-0.2.freeze_mat assembly (IMGT000139 accession number) and in the NHGRI_mGorGor1-v1.1-0.2.freeze_pat assembly (IMGT000140 accession number) compared to the Kamilah_GGO_v0 assembly (IMGT000074 accession number).

More information:
Gene table: Western lowland gorilla (Gorilla gorilla gorilla) IGHV
Gene table: Western lowland gorilla (Gorilla gorilla gorilla) IGHD
Gene table: Western lowland gorilla (Gorilla gorilla gorilla) IGHJ
Locus description: Western lowland gorilla (Gorilla gorilla gorilla) IGH