TRGV1 subgroup

TRGV9
TRGV11

Human TRGV1

Click here to see Part 1 - EcoRI and TaqI alleles and frequencies
Part 3 - Combined EcoRI/TaqI haplotypes and frequencies

Part 2 - EcoRI and TaqI haplotypes and frequencies

References for this table: Ghanem, N. et al., Immunogenetics, 30, 350-360 (1989)
Ghanem, N. et al., Hum. Genet., 86, 450-456 (1991)

Probe: pV3S clone (TRGVgammaI probe) [1]

Haplotypes Enzymes Fragments (kb) (1) Polymorphism (2) Frequencies
V1 5'V2 V2-V3 5'V4 V4 V5 V7 French [2] Lebanese [2] Tunisian [2] Black African [2] Chinese [3]
*R1 EcoRI   1.8 7.0 2.4 3.1 3.7   RS 0.69 0.61 0.61 0.50 0.73
*R2 1.8 - 9.4 3.1 3.7 RS 0.10 0.19 0.19 0.23 0.09
*R3 1.8 7.0 d d d D 0.21 0.20 0.16 0.13 0.17
*R4 1.8 7.0 6.4 3.1 3.7 I 0.00 0.00 0.04 0.13 0.00
*R5 1.6 7.0 2.4 3.1 3.7 RS 0.00 0.00 0.00 0.00 0.01
*T1 TaqI 16.0       6.0 4.2 3,7 RS 0.69 0.59 0.59 0.50 0.73
*T2 22.0   4.2 3,7 RS 0.10 0.19 0.16 0.17 0.09
*T3 17.0 d d 3,7 D 0.21 0.20 0.16 0.13 0.15
*T4 17.0 11.0 4.2 3,7 I 0.00 0.00 0.04 0.13 0.00
*T5 15.0 7.0 4.2 3,7 RS 0.00 0.00 0.01 0.07 0.00
*T6 12.8 4.2 4.2 3,7 RS 0.00 0.02 0.04 0.00 0.00
*T7 16.0 6.0 4.0 3,7 RS 0.00 0.00 0.00 0.00 0.01
*T8 17.0 d d 3 D, RS 0.00 0.00 0.00 0.00 0.02

IMGT notes:

(1) Fragments detected with the pV3S clone (TRGVgammaI probe) [1].
(2) RS, polymorphic Restriction Sites; D, Deletion; I, Insertion.

References:

[1] Lefranc, M.-P. et al., Cell, 45, 237-246 (1986).
[2] Ghanem, N. et al., Immunogenetics, 30, 350-360 (1989).
[3] Ghanem, N. et al., Hum. Genet., 86, 450-456 (1991).

Created: 12/05/1999
Authors: Violaine Moreau and Marie-Paule Lefranc