When several alleles are shown, the nucleotide mutations and amino acid changes for a given codon are indicated in red letters. These polymorphic mutations are reported in Tables of alleles.
Dashes indicate identical nucleotides. Dots indicate gaps according to the IMGT unique numbering. Blanks indicate partial sequences (blanks at the 5' and/or 3' end).
Clicking on the allele name gives access to the IMGT/GENE-DB.
Clicking on the accession number gives access to the IMGT/LIGM-DB.
1 2 3 4 5 6 7 8 8A 9 10 11 12 13 14 15 16 17 18 19 G D S V T Q T E G L V T V T E G L P V X06307 TRAV12-1*01 F V-REGION gDNA gga gac tcc gtg acc cag aca gaa ... ggc ctg gtc act gtc aca gaa ggg ttg cct gtg X06308 TRAV12D-1*01 F V-REGION gDNA --- --- --- --- --- --- --- --- ... --- --- --- --- --- --c --g --- --- --- --- AC188458 TRAV12N-1*01 F V-REGION gDNA --- --- --- --- --- --- --- --- ... --- --- --- --- --- --- --- --- --- --- --- IMGT000082 TRAV12N-1*01 F V-REGION gDNA --- --- --- --- --- --- --- --- ... --- --- --- --- --- --- --- --- --- --- --- X17173 TRAV12-1*02 F V-REGION gDNA --- --- --- --- --- --- --- --- ... --- --- --- --- --- --- --- --- --- --- --- AC004101 TRAV12D-1*02 F V-REGION gDNA --- --- --- --- --- --- --- --- ... --- --- --- --- --- --c --g --- --- --- --- AE007512 TRAV12D-1*02 F V-REGION gDNA --- --- --- --- --- --- --- --- ... --- --- --- --- --- --c --g --- --- --- --- AE008684 TRAV12D-1*02 F V-REGION gDNA --- --- --- --- --- --- --- --- ... --- --- --- --- --- --c --g --- --- --- --- L AC004406 TRAV12-1*03 ORF V-REGION gDNA --- --- --- --- --- --- --- --- ... --- --- --- --- c-- --- --- --- --- --- --- L AE007512 TRAV12-1*03 ORF V-REGION gDNA --- --- --- --- --- --- --- --- ... --- --- --- --- c-- --- --- --- --- --- --- L AE008685 TRAV12-1*03 ORF V-REGION gDNA --- --- --- --- --- --- --- --- ... --- --- --- --- c-- --- --- --- --- --- --- X02936 TRAV12D-1*03 (F) V-REGION cDNA M16677 TRAV12-1*04 (F) V-REGION cDNA --- --- --- --- --- --- --- --- ... --- --- --- --- --- --- --- --- --- --- --- X60320 TRAV12D-1*04 (F) V-REGION gDNA --- --t --- --- --- --- --- --- ... --- --- --- --- --- --c --g --- --- --- --- M38680 TRAV12-1*05 (F) V-REGION cDNA --- --- --- --- --- --- --- --- ... --- --- --- --- --- --- --- --- --- --- --- U90515 TRAV12D-1*05 (F) V-REGION cDNA --- --a --- --- --- --- --- ... --- --- --- --- --- --c --g --- --- --- --- IMGT000082 TRAV12-1*06 F V-REGION gDNA --- --- --- --- --- --- --- --- ... --- --- --- --- --- --c --g --- --- --- --- IMGT000082 TRAV12D-1*06 F V-REGION gDNA --- --- --- --- --- --- --- --- ... --- --- --- --- --- --- --- --- --- --- --- ___________________CDR1-IMGT____________________ 20 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 M L N C T Y Q T A Y S D V A F X06307 TRAV12-1*01 F V-REGION gDNA atg ctg aac tgc acc tat cag act gct tac tca ... ... ... ... ... gat gtt gcc ttt K T L T I X06308 TRAV12D-1*01 F V-REGION gDNA -a- --- --- --- --- --- --- --- a-- --t -t- ... ... ... ... ... ac- a-- --- --- AC188458 TRAV12N-1*01 F V-REGION gDNA --- --- --- --- --- --- --- --- --- --- --- ... ... ... ... ... --- --- --- --- IMGT000082 TRAV12N-1*01 F V-REGION gDNA --- --- --- --- --- --- --- --- --- --- --- ... ... ... ... ... --- --- --- --- T X17173 TRAV12-1*02 F V-REGION gDNA --- --- --- --- --- --- --- --- a-- --- --- ... ... ... ... ... --- --- --- --- K T L T I AC004101 TRAV12D-1*02 F V-REGION gDNA -a- --- --- --- --- --- --- --- a-- --t -t- ... ... ... ... ... ac- a-- --- --- K T L T I AE007512 TRAV12D-1*02 F V-REGION gDNA -a- --- --- --- --- --- --- --- a-- --t -t- ... ... ... ... ... ac- a-- --- --- K T L T I AE008684 TRAV12D-1*02 F V-REGION gDNA -a- --- --- --- --- --- --- --- a-- --t -t- ... ... ... ... ... ac- a-- --- --- K AC004406 TRAV12-1*03 ORF V-REGION gDNA -a- --- --- --- --- --- --- --- --- --- --- ... ... ... ... ... --- --- --- --- K AE007512 TRAV12-1*03 ORF V-REGION gDNA -a- --- --- --- --- --- --- --- --- --- --- ... ... ... ... ... --- --- --- --- K AE008685 TRAV12-1*03 ORF V-REGION gDNA -a- --- --- --- --- --- --- --- --- --- --- ... ... ... ... ... --- --- --- --- X02936 TRAV12D-1*03 (F) V-REGION cDNA M16677 TRAV12-1*04 (F) V-REGION cDNA --- --- --- --- --- --- --- --- --- --- --- ... ... ... ... ... --- --- --- --- K T L T I X60320 TRAV12D-1*04 (F) V-REGION gDNA -a- --- --- --- --- --- --- --- a-- --t -t- ... ... ... ... ... ac- a-- --- --- G M38680 TRAV12-1*05 (F) V-REGION cDNA --- --- --- --- --- --- --- --- --- --- --- ... ... ... ... ... --- --- -g- --- K T N I U90515 TRAV12D-1*05 (F) V-REGION cDNA -a- --- --- --- --- --- --- --- a-- --t --- ... ... ... ... ... a-- a-- --- --- K T L T I IMGT000082 TRAV12-1*06 F V-REGION gDNA -a- --- --- --- --- --- --- --- a-- --t -t- ... ... ... ... ... ac- a-- --- --- IMGT000082 TRAV12D-1*06 F V-REGION gDNA --- --- --- --- --- --- --- --- --- --- --- ... ... ... ... ... --- --- --- --- _______________C 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 F W Y V Q Y L N E A P K L L L R S S T D X06307 TRAV12-1*01 F V-REGION gDNA ttc tgg tat gtg caa tat ctc aac gaa gcc cct aaa cta ctc ctg cgg agc tcc aca gac Q V K X06308 TRAV12D-1*01 F V-REGION gDNA --- --- --- --- --- --- --- --- --- --- --- c-g g-- --- --- aa- --- --- --- --- AC188458 TRAV12N-1*01 F V-REGION gDNA --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- IMGT000082 TRAV12N-1*01 F V-REGION gDNA --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- X17173 TRAV12-1*02 F V-REGION gDNA --- --- --- --- --- --c --- --- --- --- --- --- --- --- t-- --- --- --- --- --- Q V AC004101 TRAV12D-1*02 F V-REGION gDNA --- --- --- --- --- --- --- --- --- --- --- c-g g-- --- --- --- --- --- --- --- Q V AE007512 TRAV12D-1*02 F V-REGION gDNA --- --- --- --- --- --- --- --- --- --- --- c-g g-- --- --- --- --- --- --- --- Q V AE008684 TRAV12D-1*02 F V-REGION gDNA --- --- --- --- --- --- --- --- --- --- --- c-g g-- --- --- --- --- --- --- --- H AC004406 TRAV12-1*03 ORF V-REGION gDNA --- --- --- --- --- c-- --- --- --- --- --- --- --- --- --- --- --- --- --- --- H AE007512 TRAV12-1*03 ORF V-REGION gDNA --- --- --- --- --- c-- --- --- --- --- --- --- --- --- --- --- --- --- --- --- H AE008685 TRAV12-1*03 ORF V-REGION gDNA --- --- --- --- --- c-- --- --- --- --- --- --- --- --- --- --- --- --- --- --- Q V K X02936 TRAV12D-1*03 (F) V-REGION cDNA --- --g --- --- --- --- --- --- c-g g-- --- --- aa- --- --- --- --- H M16677 TRAV12-1*04 (F) V-REGION cDNA --- --- --- --- --- c-- --- --- --- --- --- --- --- --- --- --- --- --- --- --- Q V K X60320 TRAV12D-1*04 (F) V-REGION gDNA --- --- --- --- --- --- --- --- --- --- --- c-g g-- --- --- aa- --- --- --- --- M38680 TRAV12-1*05 (F) V-REGION cDNA --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- Q V K U90515 TRAV12D-1*05 (F) V-REGION cDNA --- --- --- --- --- --- --- --- --- --- --- c-g g-- --- --- aa- --- --- --- --- Q V K IMGT000082 TRAV12-1*06 F V-REGION gDNA --- --- --- --- --- --- --- --- --- --- --- c-g g-- --- --- aa- --- --- --- --- IMGT000082 TRAV12D-1*06 F V-REGION gDNA --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- DR2-IMGT________________ 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79 N K R T E H Q G F H A T X06307 TRAV12-1*01 F V-REGION gDNA ... ... ... aac aag agg acc gag cac ... ... ... ... ... caa ggg ttc cac gcc act X06308 TRAV12D-1*01 F V-REGION gDNA ... ... ... --- --- --- --- --- --- ... ... ... ... ... --- --- --- --- --- --- AC188458 TRAV12N-1*01 F V-REGION gDNA ... ... ... --- --- --- --- --- --- ... ... ... ... ... --- --- --- --- --- --- IMGT000082 TRAV12N-1*01 F V-REGION gDNA ... ... ... --- --- --- --- --- --- ... ... ... ... ... --- --- --- --- --- --- X17173 TRAV12-1*02 F V-REGION gDNA ... ... ... --- --- --- --- --- --- ... ... ... ... ... --- --- --- --- --- --- AC004101 TRAV12D-1*02 F V-REGION gDNA ... ... ... --- --- --- --- --- --- ... ... ... ... ... --- --- --- --- --- --- AE007512 TRAV12D-1*02 F V-REGION gDNA ... ... ... --- --- --- --- --- --- ... ... ... ... ... --- --- --- --- --- --- AE008684 TRAV12D-1*02 F V-REGION gDNA ... ... ... --- --- --- --- --- --- ... ... ... ... ... --- --- --- --- --- --- AC004406 TRAV12-1*03 ORF V-REGION gDNA ... ... ... --- --- --- --- --- --- ... ... ... ... ... --- --- --- --- --- --- AE007512 TRAV12-1*03 ORF V-REGION gDNA ... ... ... --- --- --- --- --- --- ... ... ... ... ... --- --- --- --- --- --- AE008685 TRAV12-1*03 ORF V-REGION gDNA ... ... ... --- --- --- --- --- --- ... ... ... ... ... --- --- --- --- --- --- X02936 TRAV12D-1*03 (F) V-REGION cDNA ... ... ... --- --- --- --- --- --- ... ... ... ... ... --- --- --- --- --- --- M16677 TRAV12-1*04 (F) V-REGION cDNA ... ... ... --- --- --- --- --- --- ... ... ... ... ... --- --- --- --- --- --- Q E X60320 TRAV12D-1*04 (F) V-REGION gDNA ... ... ... --- --- --- --- --- --g ... ... ... ... ... g-- --- --- --- --- --- M38680 TRAV12-1*05 (F) V-REGION cDNA ... ... ... --- --- --- --- --- --- ... ... ... ... ... --- --- --- --- --- --- U90515 TRAV12D-1*05 (F) V-REGION cDNA ... ... ... --- --- --- --- --- --- ... ... ... ... ... --- --- --- --- --- --- IMGT000082 TRAV12-1*06 F V-REGION gDNA ... ... ... --- --- --- --- --- --- ... ... ... ... ... --- --- --- --- --- --- IMGT000082 TRAV12D-1*06 F V-REGION gDNA ... ... ... --- --- --- --- --- --- ... ... ... ... ... --- --- --- --- --- --- 80 81 82 83 84 84A 85 86 87 88 89 90 91 92 93 94 95 96 97 98 L H K S S S S F H L Q K S S V Q L S D X06307 TRAV12-1*01 F V-REGION gDNA ctc cat aag agc agc ... agc tcc ttc cat ctg cag aag tcc tca gtg cag ctg tca gac A X06308 TRAV12D-1*01 F V-REGION gDNA --- --- --- --- --- ... --- --- --- --- --- --- --- --- --- -c- --- --- --- --- AC188458 TRAV12N-1*01 F V-REGION gDNA --- --- --- --- --- ... --- --- --- --- --- --- --- --- --- --- --- --- --- --- IMGT000082 TRAV12N-1*01 F V-REGION gDNA --- --- --- --- --- ... --- --- --- --- --- --- --- --- --- --- --- --- --- --- Y A X17173 TRAV12-1*02 F V-REGION gDNA --- --- --- --- --- ... --- --- --- --- --- --- --- --- -ac -c- --- --- --- --- A AC004101 TRAV12D-1*02 F V-REGION gDNA --- --- --- --- --- ... --- --- --- --- --- --- --- --- --- -c- --- --- --- --- A AE007512 TRAV12D-1*02 F V-REGION gDNA --- --- --- --- --- ... --- --- --- --- --- --- --- --- --- -c- --- --- --- --- A AE008684 TRAV12D-1*02 F V-REGION gDNA --- --- --- --- --- ... --- --- --- --- --- --- --- --- --- -c- --- --- --- --- AC004406 TRAV12-1*03 ORF V-REGION gDNA --- --- --- --- --- ... --- --- --- --- --- --- --- --- --- --- --- --- --- --- AE007512 TRAV12-1*03 ORF V-REGION gDNA --- --- --- --- --- ... --- --- --- --- --- --- --- --- --- --- --- --- --- --- AE008685 TRAV12-1*03 ORF V-REGION gDNA --- --- --- --- --- ... --- --- --- --- --- --- --- --- --- --- --- --- --- --- X02936 TRAV12D-1*03 (F) V-REGION cDNA --- --- --- --- --- ... --- --- --- --- --- --- --- --- -.. .c- --- --- --- --- M16677 TRAV12-1*04 (F) V-REGION cDNA --- --- --- --- --- ... --- --- --- --- --- --- --- --- --- --- --- --- --- --- A X60320 TRAV12D-1*04 (F) V-REGION gDNA --- --- --- --- --- ... --- --- --- --- --- --- --- --- --- -c- --- --- --- --- M38680 TRAV12-1*05 (F) V-REGION cDNA --- --- --- --- --- ... --- --- --- --- --- --- --- --- --- --- --- --- --- --- A U90515 TRAV12D-1*05 (F) V-REGION cDNA --- --- --- --- --- ... --- --- --- --- --- --- --- --- --- -c- --- --- --- --- A IMGT000082 TRAV12-1*06 F V-REGION gDNA --- --- --- --- --- ... --- --- --- --- --- --- --- --- --- -c- --- --- --- --- IMGT000082 TRAV12D-1*06 F V-REGION gDNA --- --- --- --- --- ... --- --- --- --- --- --- --- --- --- --- --- --- --- --- ___CDR3-IMGT____ 99 100 101 102 103 104 105 106 107 S A L Y Y C A L S X06307 TRAV12-1*01 F V-REGION gDNA tct gcc ctg tac tac tgt gct ctg agt ga X06308 TRAV12D-1*01 F V-REGION gDNA --- --- --- --- --- --- --- --- --- -- AC188458 TRAV12N-1*01 F V-REGION gDNA --- --- --- --- --- --- --- --- --- -- IMGT000082 TRAV12N-1*01 F V-REGION gDNA --- --- --- --- --- --- --- --- --- -- G X17173 TRAV12-1*02 F V-REGION gDNA --- -g- --- --- --- --- --- t-- --- -- AC004101 TRAV12D-1*02 F V-REGION gDNA --- --- --- --- --- --- --- --- --- -- AE007512 TRAV12D-1*02 F V-REGION gDNA --- --- --- --- --- --- --- --- --- -- AE008684 TRAV12D-1*02 F V-REGION gDNA --- --- --- --- --- --- --- --- --- -- F AC004406 TRAV12-1*03 ORF V-REGION gDNA --- --- --- --- -t- --- --- t-- --- -- F AE007512 TRAV12-1*03 ORF V-REGION gDNA --- --- --- --- -t- --- --- t-- --- -- F AE008685 TRAV12-1*03 ORF V-REGION gDNA --- --- --- --- -t- --- --- t-- --- -- X02936 TRAV12D-1*03 (F) V-REGION cDNA --- --- --- --- --- --- --- -- F M16677 TRAV12-1*04 (F) V-REGION cDNA --- --- --- --- -t- --- --- t-- --- X60320 TRAV12D-1*04 (F) V-REGION gDNA --- --- --- --- --- --- --- --- --- -- M38680 TRAV12-1*05 (F) V-REGION cDNA --- --- --- --- --- --- --- --- --- U90515 TRAV12D-1*05 (F) V-REGION cDNA --- --- --- --- --- --- --- t-- --- IMGT000082 TRAV12-1*06 F V-REGION gDNA --- --- --- --- --- --- --- --- --- -- IMGT000082 TRAV12D-1*06 F V-REGION gDNA --- --- --- --- --- --- --- --- --- --
This alignment of allele is generated by IMGT/OutilAllele (Mehdi Yousfi, Chantal Ginestoux, Perrine Pégorier and Patrice Duroux).
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