IMGT Repertoire (IG and TR)

Alignment of alleles: house mouse (Mus musculus) TRAV21_DV12

When several alleles are shown, the nucleotide mutations and amino acid changes for a given codon are indicated in red letters. These polymorphic mutations are reported in Tables of alleles.

Dashes indicate identical nucleotides. Dots indicate gaps according to the IMGT unique numbering. Blanks indicate partial sequences (blanks at the 5' and/or 3' end).

Dots indicate gaps according to the IMGT unique numbering.
Blanks at the 5' and/or 3' end indicate partial sequences.
Asterisk (*) in the sequence indicate a STOP-CODON.
Letters in red correspond to amino acids which are polymorphic in the other alleles.
Colours are according to Color menu for mutations, Color menu for sequence alignments and Color menu for splicing types.
The nucleotide (s) in bold and colored in purple (splicing frame 1) or green (splicing frame 2) from the DONOR splice site are added at the beginning of the following exon in order to obtain and to complete the first CODON of the DOMAIN or REGION resulting from the splicing site. These first CODONs are in bold and colored in purple (splicing frame 1) or green (splicing frame 2)
N (Asn, asparagine) of potential N-glycosylation sites (NXS/T, where X is different from P), (N-linked glycosylation) is shown in green

Clicking on the allele name gives access to the IMGT/GENE-DB.
Clicking on the accession number gives access to the IMGT/LIGM-DB.

                                                                                                                                  
                                                  
                                                   1   2   3   4   5   6   7   8   8A  9   10  11  12  13  14  15  16  17  18  19 
                                                   D   A   K   T   T   Q       P       D   S   M   E   S   T   E   G   E   T   V  
  M94080     TRAV21/DV12*01 F   V-REGION gDNA     gat gct aag act aca caa ... cca ... gat tca atg gaa agt act gaa gga gaa acg gtg 

                                                                                                                                  
  AC005938   TRAV21/DV12*01 F   V-REGION gDNA     --- --- --- --- --- --- ... --- ... --- --- --- --- --- --- --- --- --- --- --- 

                                                                                                                                  
  AE007512   TRAV21/DV12*01 F   V-REGION gDNA     --- --- --- --- --- --- ... --- ... --- --- --- --- --- --- --- --- --- --- --- 

                                                                                                                                  
  AE008686   TRAV21/DV12*01 F   V-REGION gDNA     --- --- --- --- --- --- ... --- ... --- --- --- --- --- --- --- --- --- --- --- 

                                                                                                                                  
  X02934     TRAV21/DV12*02 (F) V-REGION cDNA     --- --- --- --- --- --- ... --- ... --- --- --- --- --- --- --- --- --- --- --- 

                                                                                                                                  
  IMGT000082 TRAV21/DV12*03 ORF V-REGION gDNA     --- --- --- --- --- --- ... --- ... --- --- --- --- --- --- --- --- --- --- --- 



                                                                              ___________________CDR1-IMGT____________________    
                                                  
                                                   20  21  22  23  24  25  26  27  28  29  30  31  32  33  34  35  36  37  38  39 
                                                   H   L   P   C   S   H   A   T   I   S   G                       N   E   Y   I  
  M94080     TRAV21/DV12*01 F   V-REGION gDNA     cac ttg cct tgt agc cac gcc aca atc agt gga ... ... ... ... ... aac gag tac atc 

                                                                                                                                  
  AC005938   TRAV21/DV12*01 F   V-REGION gDNA     --- --- --- --- --- --- --- --- --- --- --- ... ... ... ... ... --- --- --- --- 

                                                                                                                                  
  AE007512   TRAV21/DV12*01 F   V-REGION gDNA     --- --- --- --- --- --- --- --- --- --- --- ... ... ... ... ... --- --- --- --- 

                                                                                                                                  
  AE008686   TRAV21/DV12*01 F   V-REGION gDNA     --- --- --- --- --- --- --- --- --- --- --- ... ... ... ... ... --- --- --- --- 

                                                                                                                                  
  X02934     TRAV21/DV12*02 (F) V-REGION cDNA     --- --- --- --- --- --- --- --- --- --- --- ... ... ... ... ... --- --- --- --- 

                                                                                                                                  
  IMGT000082 TRAV21/DV12*03 ORF V-REGION gDNA     --- --- --- --- --- --- --- --- --- --- --- ... ... ... ... ... --- --- --- --- 



                                                                                                                  _______________C
                                                  
                                                   40  41  42  43  44  45  46  47  48  49  50  51  52  53  54  55  56  57  58  59 
                                                   Y   W   Y   R   Q   V   P   L   Q   G   P   E   Y   V   T   H   G   L   Q      
  M94080     TRAV21/DV12*01 F   V-REGION gDNA     tat tgg tac cga cag gtt cct ctt cag ggt cca gaa tac gtg act cac ggt cta caa ... 

                                                                                                                                  
  AC005938   TRAV21/DV12*01 F   V-REGION gDNA     --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- ... 

                                                                                                                                  
  AE007512   TRAV21/DV12*01 F   V-REGION gDNA     --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- ... 

                                                                                                                                  
  AE008686   TRAV21/DV12*01 F   V-REGION gDNA     --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- ... 

                                                                                                                                  
  X02934     TRAV21/DV12*02 (F) V-REGION cDNA     --- --- --- --- --- --- --- --- --- --- --- --- --t --- --- --- --- --- --- ... 

                                                                                                                                  
  IMGT000082 TRAV21/DV12*03 ORF V-REGION gDNA     --- --- --- --- --- --- --- --- --- --- --- --- --t --- --- --- --- --- --- ... 



                                                  DR2-IMGT________________                                                        
                                                  
                                                   60  61  62  63  64  65  66  67  68  69  70  71  72  73  74  75  76  77  78  79 
                                                                   Q   N   T   T   N                       S   M   A   F   L   A  
  M94080     TRAV21/DV12*01 F   V-REGION gDNA     ... ... ... ... caa aat aca acc aat ... ... ... ... ... agt atg gct ttc ctg gct 

                                                                                                                                  
  AC005938   TRAV21/DV12*01 F   V-REGION gDNA     ... ... ... ... --- --- --- --- --- ... ... ... ... ... --- --- --- --- --- --- 

                                                                                                                                  
  AE007512   TRAV21/DV12*01 F   V-REGION gDNA     ... ... ... ... --- --- --- --- --- ... ... ... ... ... --- --- --- --- --- --- 

                                                                                                                                  
  AE008686   TRAV21/DV12*01 F   V-REGION gDNA     ... ... ... ... --- --- --- --- --- ... ... ... ... ... --- --- --- --- --- --- 

                                                                                                                                  
  X02934     TRAV21/DV12*02 (F) V-REGION cDNA     ... ... ... ... --- --- --- --- --- ... ... ... ... ... --- --- --- --- --- --- 

                                                                                                                                  
  IMGT000082 TRAV21/DV12*03 ORF V-REGION gDNA     ... ... ... ... --- --- --- --- --- ... ... ... ... ... --- --- --- --- --- --- 



                                                                                                                                  
                                                  
                                                   80  81  82  83  84 84A  85  86  87  88  89  90  91  92  93  94  95  96  97  98 
                                                   I   A   S   D   R       K   S   S   T   L   I   L   T   H   V   S   L   R   D  
  M94080     TRAV21/DV12*01 F   V-REGION gDNA     att gcc tct gac aga ... aag tca agc acc ttg atc ctg act cat gtc agc ctg aga gac 

                                                                                                                                  
  AC005938   TRAV21/DV12*01 F   V-REGION gDNA     --- --- --- --- --- ... --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

                                                                                                                                  
  AE007512   TRAV21/DV12*01 F   V-REGION gDNA     --- --- --- --- --- ... --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

                                                                                                                                  
  AE008686   TRAV21/DV12*01 F   V-REGION gDNA     --- --- --- --- --- ... --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

                                                                                           S           P                          
  X02934     TRAV21/DV12*02 (F) V-REGION cDNA     --- --- --- --- --- ... --- --- --- --- -c- --- --- c-- --- --- --- --- --- --- 

                                                                                                       P                          
  IMGT000082 TRAV21/DV12*03 ORF V-REGION gDNA     --- --- --- --- --- ... --- --- --- --- --- --- --- c-- --- --- --- --- --- --- 



                                                                          _____CDR3-IMGT______
                                                  
                                                   99 100 101 102 103 104 105 106 107 108 
                                                   A   A   V   Y   H   C   I   L   R   V  
  M94080     TRAV21/DV12*01 F   V-REGION gDNA     gcg gct gtg tac cac tgt atc ctg aga gta g

                                                                                          
  AC005938   TRAV21/DV12*01 F   V-REGION gDNA     --- --- --- --- --- --- --- --- --- --- -

                                                                                          
  AE007512   TRAV21/DV12*01 F   V-REGION gDNA     --- --- --- --- --- --- --- --- --- --- -

                                                                                          
  AE008686   TRAV21/DV12*01 F   V-REGION gDNA     --- --- --- --- --- --- --- --- --- --- -

                                                                                          
  X02934     TRAV21/DV12*02 (F) V-REGION cDNA     --- --- --- --- --- --- --- --- --- --- -

                                                                                          
  IMGT000082 TRAV21/DV12*03 ORF V-REGION gDNA     --- --- --- --- --- --- --- --- --- --- -

This alignment of allele is generated by IMGT/OutilAllele (Mehdi Yousfi, Chantal Ginestoux, Perrine Pégorier and Patrice Duroux).

Created:: 05/09/2022
Last updated:: 22/09/2023
Authors:: Guilhem Zeitoun