IMGT Repertoire (IG and TR)

Alignment of alleles: house mouse (Mus musculus) TRAV4-4_DV10

When several alleles are shown, the nucleotide mutations and amino acid changes for a given codon are indicated in red letters. These polymorphic mutations are reported in Tables of alleles.

Dashes indicate identical nucleotides. Dots indicate gaps according to the IMGT unique numbering. Blanks indicate partial sequences (blanks at the 5' and/or 3' end).

Dots indicate gaps according to the IMGT unique numbering.
Blanks at the 5' and/or 3' end indicate partial sequences.
Asterisk (*) in the sequence indicate a STOP-CODON.
Letters in red correspond to amino acids which are polymorphic in the other alleles.
Colours are according to Color menu for mutations, Color menu for sequence alignments and Color menu for splicing types.
The nucleotide (s) in bold and colored in purple (splicing frame 1) or green (splicing frame 2) from the DONOR splice site are added at the beginning of the following exon in order to obtain and to complete the first CODON of the DOMAIN or REGION resulting from the splicing site. These first CODONs are in bold and colored in purple (splicing frame 1) or green (splicing frame 2)
N (Asn, asparagine) of potential N-glycosylation sites (NXS/T, where X is different from P), (N-linked glycosylation) is shown in green

Clicking on the allele name gives access to the IMGT/GENE-DB.
Clicking on the accession number gives access to the IMGT/LIGM-DB.

                                                                                                                                 
                                                 
                                                  1   2   3   4   5   6   7   8   8A  9   10  11  12  13  14  15  16  17  18  19 
                                                  G   D   Q   V   E   Q   S   P       S   A   L   S   L   H   E   G   T   D   S  
  AC004102   TRAV4-4/DV10*01 F V-REGION gDNA     ggg gat cag gtg gag cag agt cct ... tca gcc ctg agc ctc cac gag gga acc gat tct 

                                                                                                                                 
  AE007512   TRAV4-4/DV10*01 F V-REGION gDNA     --- --- --- --- --- --- --- --- ... --- --- --- --- --- --- --- --- --- --- --- 

                                                                                                                                 
  AE008685   TRAV4-4/DV10*01 F V-REGION gDNA     --- --- --- --- --- --- --- --- ... --- --- --- --- --- --- --- --- --- --- --- 

                                                                                                                          G      
  IMGT000082 TRAV4-4/DV10*02 F V-REGION gDNA     --a --- --- --- --- --- --- --- ... --- --- --- --- --- --- --- --- --- -g- --- 



                                                                             ___________________CDR1-IMGT____________________    
                                                 
                                                  20  21  22  23  24  25  26  27  28  29  30  31  32  33  34  35  36  37  38  39 
                                                  A   L   R   C   N   F   T   T   T   M                               R   S   V  
  AC004102   TRAV4-4/DV10*01 F V-REGION gDNA     gct ctg aga tgc aat ttt acg acc acc atg ... ... ... ... ... ... ... agg agt gtg 

                                                                                                                                 
  AE007512   TRAV4-4/DV10*01 F V-REGION gDNA     --- --- --- --- --- --- --- --- --- --- ... ... ... ... ... ... ... --- --- --- 

                                                                                                                                 
  AE008685   TRAV4-4/DV10*01 F V-REGION gDNA     --- --- --- --- --- --- --- --- --- --- ... ... ... ... ... ... ... --- --- --- 

                                                                                                                          A      
  IMGT000082 TRAV4-4/DV10*02 F V-REGION gDNA     --- --- --- --- --- --- --- --- --- --- ... ... ... ... ... ... ... --- gc- --- 



                                                                                                                 _______________C
                                                 
                                                  40  41  42  43  44  45  46  47  48  49  50  51  52  53  54  55  56  57  58  59 
                                                  Q   W   F   R   Q   N   S   R   G   S   L   I   S   L   F   Y   L   A   S      
  AC004102   TRAV4-4/DV10*01 F V-REGION gDNA     cag tgg ttc cga cag aat tcc agg ggc agc ctc atc agt ttg ttc tac ttg gct tca ... 

                                                                                                                                 
  AE007512   TRAV4-4/DV10*01 F V-REGION gDNA     --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- ... 

                                                                                                                                 
  AE008685   TRAV4-4/DV10*01 F V-REGION gDNA     --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- ... 

                                                              Q                                   N                              
  IMGT000082 TRAV4-4/DV10*02 F V-REGION gDNA     --- --- --- -a- --- --- --- --- --- --- --- --- -a- c-- --- --- --- --- --- ... 



                                                 DR2-IMGT________________                                                        
                                                 
                                                  60  61  62  63  64  65  66  67  68  69  70  71  72  73  74  75  76  77  78  79 
                                                                  G   T   K   E   N                       G   R   L   K   S   A  
  AC004102   TRAV4-4/DV10*01 F V-REGION gDNA     ... ... ... ... gga aca aag gag aat ... ... ... ... ... ggg agg cta aag tca gca 

                                                                                                                                 
  AE007512   TRAV4-4/DV10*01 F V-REGION gDNA     ... ... ... ... --- --- --- --- --- ... ... ... ... ... --- --- --- --- --- --- 

                                                                                                                                 
  AE008685   TRAV4-4/DV10*01 F V-REGION gDNA     ... ... ... ... --- --- --- --- --- ... ... ... ... ... --- --- --- --- --- --- 

                                                                                                                              T  
  IMGT000082 TRAV4-4/DV10*02 F V-REGION gDNA     ... ... ... ... --- --- --- --- --- ... ... ... ... ... --- --- t-- --- --- a-- 



                                                                                                                                 
                                                 
                                                  80  81  82  83  84 84A  85  86  87  88  89  90  91  92  93  94  95  96  97  98 
                                                  F   D   S   K   E   R   R   Y   S   T   L   H   I   R   D   A   Q   L   E   D  
  AC004102   TRAV4-4/DV10*01 F V-REGION gDNA     ttt gat tct aag gag cgg cgc tac agc acc ctg cac atc agg gat gcc cag ctg gag gac 

                                                                                                                                 
  AE007512   TRAV4-4/DV10*01 F V-REGION gDNA     --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

                                                                                                                                 
  AE008685   TRAV4-4/DV10*01 F V-REGION gDNA     --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

                                                      N                   S                                                      
  IMGT000082 TRAV4-4/DV10*02 F V-REGION gDNA     --c a-- --- --- --- ... a-- --- --- --- --- --- --- --- --- --- --- --- --- --- 



                                                                         ___CDR3-IMGT____
                                                 
                                                  99 100 101 102 103 104 105 106 107 
                                                  S   G   T   Y   F   C   A   A   E  
  AC004102   TRAV4-4/DV10*01 F V-REGION gDNA     tca ggc act tac ttc tgt gct gct gag g

                                                                                     
  AE007512   TRAV4-4/DV10*01 F V-REGION gDNA     --- --- --- --- --- --- --- --- --- -

                                                                                     
  AE008685   TRAV4-4/DV10*01 F V-REGION gDNA     --- --- --- --- --- --- --- --- --- -

                                                                                     
  IMGT000082 TRAV4-4/DV10*02 F V-REGION gDNA     --- --- --- --- --- --- --- --- --- -

This alignment of allele is generated by IMGT/OutilAllele (Mehdi Yousfi, Chantal Ginestoux, Perrine Pégorier and Patrice Duroux).

Created:: 05/09/2022
Last updated:: 22/09/2023
Authors:: Guilhem Zeitoun