IMGT Repertoire (IG and TR)

The IGHC protein display numbering is according to the IMGT unique numbering for C-DOMAIN and C-LIKE-DOMAIN.

Only the *01 allele of each functional, ORF and in-frame pseudogenes C-REGION is shown.

Letters in red correspond to amino acids which are polymorphic in the other alleles.
For C-REGIONs, letters in bold correspond to additional positions in the IMGT unique numbering.
For C-REGIONs, letters between parentheses correspond to amino acids resulting from the splicing.

N (Asn, asparagine) of potential N-glycosylation sites (NXS/T, where X is different from P), (N-linked glycosylation) is shown is green (site is underlined in CHS and in pages edited before 14/10/2009).

                                                                                                                                     
                                                                                                                                     
TRBC genesAccNum
                 A       AB      B           BC         C     CD      D          DE           E      EF   F                FG                  G     
              (1-15)          (16-26)     (27-38)    (39-45)       (77-84)                 (85-96)     (97-104)         (105-117)          (118-128) 
          ——————————————>   ——————————>              ——————>       ———————>              ———————————>  ———————>                            ——————————>
          1        10  15   16     2326 27        38 3941 45       77 80 84              85  89    96  97   104 105                   117 118121  128    
  87654321|........|....|123|......|..| |..........| |.|...|1234567|..|...|12345677654321|...|......|12|......| |......123456654321.....| |..|......|
TRBC1AAEX02035465F
 (E)DLQKVTPPTVTVFEPSEAEISR..TQKATLVCLAT GFYP....DHVE LSWWVNGKEVTS..GFSTDPQPYKERPSE.NDSSYCLSSRLRVSASFWH.NPRNHFRC QVQFYGLGDDDEWKYDRVKPITQNI SAEAWGRA
  [EX2]                  [EX3]                     [EX4]
TRBC1AAEX02035465F
(D)CGFTS  (V)SYHQGVLSATILYEILLGKATLYAVLVSILVLMAK  VKRKGS
      CONNECTING-REGION    | TRANSMEMBRANE-REGION |CYTOPLASMIC-REGION
IMGT notes:
(1): Functional but have a splicing frame 0 (sf0) between EX3 and EX4