The IGHC protein display numbering is according to the IMGT unique numbering for C-DOMAIN and C-LIKE-DOMAIN.

N (Asn, asparagine) of potential N-glycosylation sites (NXS/T, where X is different from P), (N-linked glycosylation) is shown is green (site is underlined in CHS and in pages edited before 14/10/2009).

The hinge exon(s) are shown at the end of the protein display.

               A       AB      B          BC        C     CD      D          DE           E      EF   F          FG            G              CHS
            (1-15)          (16-26)    (27-38)   (39-45)       (77-84)                 (85-96)     (97-104)   (105-117)    (118-128)   
        -------------->   ---------->            ------>       ------->              ----------->  ------->               ---------->
IGHC genesAccNum
        1        10  15   16  20 2326 27      38 3941 45       77 80 84              85  89    96  97   104 105       117 118        130       140      150
87654321|........|....|123|...|..|..| |........| |.|...|1234567|..|...|12345677654321|...|......|12|......| |...........| |...........|.........|.........|
CH1
IGHA1X51647
....DPATTPILFPLSLPCPLS....GQPVVVGCLIQ GFFPL.GPLN VKWTISG.......ENVTFPPVQLDTS.....GLYTTSSLLNLTDEEC....PTCVAC HVEHN....EVDR YLILPCP
IGHA2X82108
...DLENSSPDLIPLPCPILEP....GEPMVIGCLIR GFFPR.GPLT VTWNVSG.......ESVIFPPVPSPPS.....SLYTTYSLLRLPAEQC..PEENSVAC RVEHN....NKGQ DVTVPSPP
IGHA3X82109
....ATAAPPSLFPLIHPRCALKDT.PATVIAGCLIR GFFPL.GPLS VSWNASG.......KNVTFPPVPSGTS.....GPYTTCSLLSLTPEQC..PEDHNVVC HVEHN...YDEGQ NLTVLYP
IGHA4X82110
....VPATPPIIFPLTCPGCVLKDT.SATIVAGCLIR GFFPR.GPLG VTWNDNR.......ANLTFPPVQSATS.....SLYTTCSVLSLPAEQC..PAGNSVAC RVEHN....NKRQ DLTVPCL
IGHA5X82111
....ATAASPRLFPLIHPRCALKDT.SATVIAGCLIR GFFPL.GPLS VSWNASG.......KNVTFPPVPSGTS.....GPYTTCSLLSLTPEQC..PEDDNVVC HVEHN...YDKGQ NLTVLYP
IGHA6X82112
...DPVNTRPILIPLPSPILGP....GEPVVIGCLIR GFFPL.GPLS VTWNTSG.......ENLTFPPVQSATS.....SLYTTCSLLRLLAEQC..PEENSVAC HVEHN...YDKGQ HVTVPSPP
IGHA7X82113
....EPAATPDIFPLNLPLRVSDGN.SQTVVVGCLIR GFFPP.SPLR VSWNVSRENM....SVYNFPPAPTGTS.....GPYTACSELILPVTQC..LEYDSAAC HVEYN...SVINE SLPVPFP
IGHA8X82114
....ASATTPGIYPLSLPLHVSDGN.SQPVVVGCLID GFFPP.GPLR VSWNVSRENIT...SVYNFPPAPTGTS.....GPYTACSELILPDTQC..LRHQSAAC HVEYN....SVNQ SLLVPYP
IGHA9X82115
....DPATTPSLFPLSLPCPEC....AHPVVVGCLIR GFFPL.GPLN VSWNGSE.......GGVIFPPVPSPSS.....SLYTTSSLLSLTDDQC..PRDGNVTC HVEHN...YDEGQ DLTVPCQ
IGHA10X82116
....EAATNLELFPMTCPRPRP....EQTVVVGCLIR GFPL..DPLS VSWDVSGENV....RVYNFPPAQSGTS.....GLNTACSLLSLPSDQC..PADDNVTC HVVHN....NEGQ DLPVPCHP
IGHA11X82117
....EPATTPGIYPLSLPLRVSDGN.SQTVVVGCLIR GFFPL.GPLR VSWNVSRENV....SIYNFPPAPTGTS.....GPYTACSELILPDTQC..LEYDSAAC HVEYN...SVINE SLPVPFP
IGHA12X82118
....ASATTPSLFPLILPGPVS....GETVVVGCLIR GFFPL.GPLN VSWNGSE.......GDVIFPPVPSPPS.....SLYTTSSLLNLTIEEC....PKCVIC HVEHN....EVHR DLILPCP
IGHA13X82119
........................N.SQYVVVGCLIR GFFPP.GPLS VSWTVNGENV....SAYNFPPAQSGTS.....GPYTACSELILPVTQC..LGQKSAAC HVEYN...SVINE SLPVPFP
IGHA14AF314407
..................................... .......... .........................................ILPPEEC..PAGNCVAC HVEHN...DDEGQ DLTVPCPP
IGHEAY386696
....VSIQAPSVFPLASCCRGATAR.AASVTLGCLVK GYFP..EPVS VTWDAGTLNS....STVTLPAVTLDT......GLSTTVSQVTISGAWA....KQRFTC SVAHTPSATHTNK TFQ
IGHGL29172
....GQPKAPSVFPLAPCCGDTP...SSTVTLGCLVK GYLP..EPVT VTWNSGTLTN....GVRTFPSVRQSS......GLYSLSSVVSVTSS......SQPVTC NVAHPA..TNTKV DKTV
IGHMJ00666 (c)
....VSLSSPTLYPLVSCEGALTD..GNLVAMGCLAR DFLP..SSVT FSWSFKNNSEISSRTVRTFPVVKRGD.......KYMATSQVLVPSKDVLQGTEEYLVC KVQHS....NSNR DLRVSFP
CH2
IGHA1X51647
......CGEPSLSLQRPDLRDLLL..GSDASLTCTLR GLKDP.KDAV FTWEPTNGNE....PVQQSPQRDPCG.......CYSVSSVLPGCAETW..TAGTEFTC TVTHPE.IEGSSL TATIRKDT
IGHA2X82108
......CGKPSLSLQRPDLGDLLL..NSNASLTCTLR GLLNP.EGAV FTWEPTFGKE....PVQQSPQLDHCG.......CYSVSSVLPGCAVLW..NAGTEFTC TVTHPE.IEGDSL TGTISKDT
IGHA3X82109
......CGEPSLSLQRPDIGDLLL..ESNASLTCTLS GLKDP.EGAV FTWNPTNGNE....PVQQSTQSYPCG.......CYSVSSVLPGCAEPW..NAGTEFTC TVTHPE.IEGGSL TATISR
IGHA4X82110
......CGKPSLSLQRPDLGDLLL..DSNASLTCTLR GLLNP.EGAV FTWNPTNGKE....PVQQSAQRDHCG.......CYSVSSVLPGCAEPW..NAGTVFTC TVTHPE.IDSGSL TATISKDT
IGHA5X82111
......CGEPSLSLQRPDLGDLLL..NSNASLTCTLR GLLDP.EGAV FTWEPTFGKE....PVQLSPRLDHCG.......CYSVSSVLPGCAAAW..NAGTKFNC TVTHPE.IKGVSL TDIISKDT
IGHA6X82112
......CGEPSLSLQRPFLRDLLL..NSNASLTCTLR GLKNP.EGAV FTWEPTNGNK....PVQQSVQSYPCG.......CYSVSSVLPGCAEPW..NAGTEFTC TVTHPE.IEGGPL TAKISKDT
IGHA7X82113
......CEEPSLSLQRPDLRDLLL..GSDASLTCTLR GLKYP.EDAV FTWEPTNGNE....PVQQSPQRDPCG.......CYSVSSVLPGCAEPW..NAGTEFTC TVTHPE.IEGGSL TATISKDT
IGHA8X82114
.......CQPSLSLQRPDIGDLLL..GRDASLTCTLS GLKDP.EGAV FTWEPTNGNE....PVQQRAQRDLSG.......CYSVSSVLPSSAETW..KVRTEFTC TVTHPE.IEGGSL TATISKDT
IGHA9X82115
......CGEPSLSLQRPDIGDLLL..ESKASLTCTLS GLKDP.EGAV FTWEPTNGNE....PVQQSVQSYPCG.......CYSVSSVLPGCAEPW..NAGTEFTC TVTHPE.IEGGSL TATISISR
IGHA10X82116
......CGEPSLSLQRPDIGDLLL..ESKASLTCTLS GLKDP.EGAV FTWEPTNGNE....PVQQSTQSYPCG.......CYSVSSVLPGCAEPW..NAGTEFTC TVTHPE.IEGGSL TATISR
IGHA11X82117
......CEEPSLSLQRPDLRDLLL..GSDASLTCTLR GLKDP.EGAV FTWEPTNGNE....PVQQSPQRDPCG.......CYSVSSVLPGCAEPW..NAGTEFTC TVTHPE.IEGSSL TATISKDT
IGHA12X82118
......CGEPSLSLQRPDIGDLLL..ESKASLTCTLS GLKDP.EGAV FTWEPTNGNE....PVQQSVQSYPCG.......CYSVSSVLPGCAEPW..NAGTEFTC TVTHPE.IEGGSL TAKISR
IGHA13X82119
.......CQPSLSLQRPDLGDLLL..GRDASLTCTLS GLKNP.EDAV FTWEPTNGNE....PVQQRAQRDLSG.......CYSVSSVLPSSAETW..KARTEFTC TVTHPE.IDSGSL TATISR
IGHA14AF314407
.......CQPSLSLQRPDLGDL
IGHEAY386696
.ACSVSFTPPAVRLFHSSCDPREN.DTYTVQLLCLIS GYTP..GDIE VTWLVDGQKDP..NMFSITAQPRQEG......KLASTHSELNITQGEW..ASKRTYTC RVAYQ....GELF EAHARECT
IGHGL29172
..PPELLGGPSVFIFPPKPKDTLMI.SRTPEVTCVVV DVSEDDPEVQ FTWYINNEQVR...TARPPLREQQFN......STIRVVSTLPIAHEDW..LRGKEFKC KVHNKA..LPAPI EKTISKAR
IGHMJ00666 (c)
...VDSELPPNVSVFIPPRDSFSGSGTRKSRLICQAT GFSP..KQIS VSWLRDGQKVES..GVLTKPVEAETKGA..GPATFSISSMLTITESDW..LSQSLYTC RVDHR....GIFF DKNVSMSSECS
CH3
IGHA1X51647
....GSLTPPQVHLLPPPSEELAL..NALVTLTCLVR GFSP..KDVL VYWTNKGVVVPKD.SFLVWKPLPEPGQE...PTTYAVTSLLRVSAEDW..NQGDSYSC VVGHEG.LAEHFT QKTIDRQA...GKPTHVNVSVVVADVEGVCY
IGHA2X82108
....GSLIPPQVHLLPPPSEELAL..NALVTLTCLVR GFSP..KDVL VSWTHNGTPVVPKDSYLVWKPLREPGQD...PTTYAITSLLRVPAEDW..NQGDSYSC VVGHEG.LAEHFT QKTIDRLA...GKPTHVNVSVVVADVEGVCY
IGHA3X82109
....GSLTPPQVHLLPPPTEELAL..NALVTLTCLVR GFSP..KDVL VSWTHNGTLVVPKDSFLVWKPLPEPGQE...PTTYAVTSLLRVPAEDW..NQGDSYSC VVGHEG.LAEHFT QKTIDRLA...GKPTHVNVSVVVADVEAVCY
IGHA4X82110
....GSLIPPQVHLLPPPSEELAL..NALVTLTCLVR GFSP..KDVL VYWTNKGLQVPKD.SFLVWKPLPEPGQE...PTTYAVTSLLRVPAEDW..NQNESYTC VVGHEG.LAEHFT QKTIDRLA...GKPTHVNVSVVVADVEGVCY
IGHA5X82111
....GVVIAPQVHLLPPPSDELAL..NALVTLTCLVR GFSP..KDVL VYWTNKGVEVPKD.SFLVWKPLPEPGQE...PTTYAVTSLLRVPAEDW..NQNESYTC VVGHEG.LAEHFT QKTIDRLA...GKPTHVNVSVVVADVEGVCY
IGHA6X82112
....GAIIPPQVHLLPPPSEELAL..NELVTLTCLVR GFSP..KDVL VYWTNKGVNVPEN.SFLVWKPLPEPGQE...PTTYAVTSLLRVPAEDW..NQNESYTC VVGHEG.LAEHFT QKTIDRLS...GKPTHVNVSVVVADVEGVCY
IGHA7X82113
....GSLTPPQVHLLPPPSEELAL..NALVTLTCLVR GFSP..KDVL VYWRKKDVEVPEN.SFLVWKPLPEPGQD...PTTYAVTSLLRVSAEDW..NQGDSYTC VVGHEG.LAEHFT QKTIDREA...GKPTHVNVSVVVADVEAVCY
IGHA8X82114
....GSLTPPLVHLLPPPSEELAL..NALVTLTCLVR GFSP..KDVL VSWTHNGTPVVPKDSFLVWKPLPEPGQD...PTTYAATSLLRMSAEDW..NQGDSYNC VVGHEG.LAEHFT QKTIDRLA...GKPTHVNVSVVVADVEGVCY
IGHA9X82115
....GSLTPPQVHLLPPPTEELAL..NEQVTLTCLVQ GFSP..KDVL VSWTHNGTLVVPKDSYLVWKPLPEPGQD...PTTYAVTSLLRVSAEDW..NQGDSYSC VVGHEG.LAEHFT QKTIDRQA...GKPTHVNVSVVVADVEAVCY
IGHA10X82116
....GIIIPPLVHLLPPPSDELAL..NALVTLTCLVR GFSP..KDVL VYWTNKGVNVPEN.SFLLWKPLPEPGQE...PTTYAITSLLRVPAEDW..NQNESYTC VVGHEG.LAEHFT QKTINREA...GKPTHVNVSVVVADVEGVCY
IGHA11X82117
....GSLTPPLVHLLPPPSEELAL..NALVTLTCLVR GFSP..KDVL VSWTNKGVKVPEN.SFLVWKPLPEPGQD...PTTYAVTSLLRVPAEDW..NQNESYSC VVAHEG.LAEHFT QKTIDRLA...GKPTHVNVSVVVADVEAVCY
IGHA12X82118
....GSLTPPQVHLLPPPSEELAN..NALVTLTCLGQ GFSP..KDVL VYWTNKGTVVLKE.SYLVWKPLPEPGQE...PTTYAVTSLLRVPAEDW..NQNESYTC VVGHEG.LAEHFT QKTINREA...GKPTHVNVSVVVADVEGVCY
IGHA13X82119
....GVVTPPQVHLLPPPSEELAL..NEQVTLTCLVR GFSP..KDVL VSWRHQGQEVPED.SFLVWKSMPESSQD...KATYAITSLLRVPAEDW..NQGDTYSC MVGHEG.LAEHFT QKTIDRLA...GKPTHVNVSVVVADVEAVCY
IGHEAY386696
...DYEPRGVSTYLSSPSPLDLYV..HKSPKLTCLVV DLASEEGVSL VWSRDSGKPVD....PDPWKSDKQFN......ATVIIRSTLPVDAQDW..IDGEIFKC TVTHPD..LPTAI VRSISKAQ
IGHGL29172
....GQPLEPKVYTMGPPREELS...SRSVSLTCMIN GFYP..SDIS VEWEKNGKAED...NYKTTPAVLDSD......GSYFLYSKLSVPTSEW..QRGDVFTC SVMHEA.LHNHYT QKSISRSP...GK
IGHMJ00666 (c)
....TPSPGIQVFPIAPSFADTFL..SKSARLICLVT DLTTY.GSLN ISWASHNGKAL...DTHMNITESHPN......ATFSAMGEASVCAEDW..ESGEQFTC TVTHAD..LPFPL KHTISKSR
CH4
IGHEAY386696
....GKRATPEVHLFTPPEEDQGS..RDQLTLTCLVQ NFFP..ADIF VDWLRNGQHMPS.GQQSTTEPRLAGGS....NQTYFVFSRLEVSRADW..EQNIPFTC RVVHEAVTDTRTL LKTVSKRP...GK
IGHMJ00666 (c)
...EVAKHPPAVYVLPPAREQLVL..RESATVTCLVK GFSP..ADVF VQWQQRGQPLSSD.KYVTSAPAPEPQA....PGLYFTHSTLTVTEEDW..NSGETFTC VVGHEA.LPHMVT ERTVDKST...GKPTLYNVSLIMSDTASTCY
CONNECTING-REGION, TRANSMEMBRANE-REGION and CYTOPLASMIC-REGION 
                           M1                           M2
IGHEAY386696
         EDVQDLCTEGAEHEELDGLWTSTCIFAGLFLLSTSCSATVLLLK   VKWVFTAVLRESPQASHDYTNVLQLRA
IGHMK01357 (c)
              EGEVGAEEEGFENLWTTASTFIVLFLLSLFYSTTVTLFK   VK
       CONNECTING-REGION   |   TRANSMEMBRANE-REGION     |   CYTOPLASMIC-REGION
HINGE-REGION
IGHA1X51647
DTHSSCPPTS
IGHA2X82108
ACNESTIEPPTTPTCPCPCPSPS
IGHA3X82109
ECKDPNSDPTPCPCPPIT
IGHA4X82110
ACNKPTIEPPTKPTCPCPCPSPS
IGHA5X82111
ECQPPTPSPTTPTTATTSGPTPS
IGHA6X82112
ECQPPTPGPSDTTTCPCPCPSPS
IGHA7X82113
DPCEQCHCPS
IGHA8X82114
DCCPANSCCTCPSSSSRNLISG
IGHA9X82115
DCHCYCPPTS
IGHA10X82116
ECREPIIDPTPCPTT
IGHA11X82117
DPCEQCHCPS
IGHA12X82118
DCSIPPIT
IGHA13X82119
DCCPANSCCTCPSSSSRNLISG
IGHA14AF314407
EDPCKNCPTISRSRFTAH
IGHGL29172
APSTCSKPTCP
IMGT note:
(c) cDNA Sequence