Only the *01 allele of each functional, ORF and in-frame pseudogenes C-REGION is shown.
Letters in red correspond to amino acids which are polymorphic in the other alleles.
For C-REGIONs, letters in bold correspond to additional positions in the IMGT unique numbering.
For C-REGIONs, letters between parentheses correspond to amino acids resulting from the splicing.
N (Asn, asparagine) of potential N-glycosylation sites (NXS/T, where X is different from P), (N-linked glycosylation) is shown is green (site is underlined in CHS and in pages edited before 14/10/2009).
The IGHC protein display numbering is according to the IMGT unique numbering for C-DOMAIN and C-LIKE-DOMAIN.
A AB B BC C CD D DE E EF F FG G CHS | |||||
(1-15) (16-26) (27-38) (39-45) (77-84) (85-96) (97-104) (105-117) (118-128) | |||||
——————————————> ——————————> ———————————> ——————> ———————> ———————————> ———————> ————————————> ——————————> | |||||
C Genes | AccNum | 1 10 15 16 20 2326 27 38 3941 45 77 80 84 85 89 96 97 104 105 117 118121 130 140 150 |
|||
87654321|........|....|123|...|..|..| |..........| |.|...|1234567|..|...|12345677654321|...|......|12|......| |...........| |..|........|.........|.........| | |||||
CH1 | |||||
Danrer | IGHZ | BX649502 | F | ...(X)ETLTAPVVFKMSQCSSS...TDSLIIGCLAS EFSP....DSVN FRWSSNGNEMK...NVTQHSTANN...........LKFSYITITKKQR...YQSDIMC TADHP....SKTV NETFST | |
CH2 | |||||
Danrer | IGHZ | BX649502 | F | ..........(A)PTLSLVLVPT...EKNTFAMCVIE DFYT....ENIT VRWKENNIYKQ...SQTNLEYKLNMN.......GLHTALSLYKLNEIV..IPNTEYTC EVSHR....GKTF HKTQNFT | |
CH3 | |||||
Danrer | IGHZ | BX649502 | F | ....(A)KFRLMLKPPMVREMFI...NNRIVLQAVVS GDL......STA VKEASVSCKMDNVPINSVSQENESQ.........HVKIYNVPVDTTKW..FNGGKVTC TTRDTL..NNKDI KQEIYFNKG | |
CH4 | |||||
Danrer | IGHZ | BX649502 | F | .....(D)GQEPSVKMYKPDDIS...TKQISYVCEVS SPNL....GDVY IMWKVNNTFTE...GKSSDPIQQQG........STSVVSILTISKKEFE.NPETTINC AVVHAN..MKDTA SPLLKSTSKSKQTECDD | |
M | |||||
M1 M2 | |||||
Danrer | IGHZ | BX649502 | F | .EPPEPETGFALHCNEDVLEEDEFRSLWSTATSFIFLFLFSLTYSAVLSLFT MKQ | |
CONNECTING_REGION | TRANSMEMBRANE-REGION | CYTOPLASMIC-REGION |
IMGT notes:
Danrer: Danio rerio (leopard danio)