Particularities in protein designations: Human immunoglobulins: New and Newm

Click here to see Part 2 - Protein display showing the discrepancies between sequences.

Part 1 - Discrepancies between protein names in publications and databases.

Click here to see Protein Newm

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Protein New  ( human Bence Jones protein ) (1)
Chain Domain Protein name as mentioned in Databases Accession number Discrepancies between amino acid sequences in databases
publications databases 1 90 IMGT unique numbering for V-REGIONs
1 74 Kabat numbering
Lambda V New [1] - GenPept -     
NEW Kabat 007436 PCA
(2)		 A  
Ig l light chain V-I region (New) PIR L1HUNW
A01964		 Q G  
SWISS-PROT P01701 Q G  
- - PDB -  
C New [1] - GenPept -  
NEW Kabat 013785  
- PIR -  
- SWISS-PROT -  
- - PDB -  
Heavy(1) - - - - -  

IMGT notes:
(1)Free lambda light chain without heavy chain associated.
(2)PCA: Pyrrolidone Carboxylic Acid.

Reference:
[1] Langer, B. et al., Hoppe-Seyler's Z. Physiol. Chem., 349, 945-951 (1968). PMID: 4177823

Created: 03/04/2001
Author: Lisa Truong