Functionality is shown between parentheses, (F) and (P), when the accession number refers to rearranged genomic DNA or cDNA and the corresponding germline gene has not yet been isolated.
The IMGT allele table refers to the V-REGION polymorphism. It does not include polymorphisms in the other parts of the V-GENE. V-REGION alleles are only described for genes which have at least one Functional or ORF allele. The accession number of a reference sequence is given for each allele.
Nucleotide mutations and amino acid changes in CDR3-IMGT of rearranged sequences are not taken into account for the description of polymorphism.
Click on a gene name to get the alignment of the corresponding V-REGION alleles.
Click on an accession number to get the sequence and additional information (IMGT annotations, IMGT flat file, Coding regions...).
| TRGV subgroup |
TRGV gene name |
Fct | TRGV allele name |
Breed | Accession number | confirmed by genetics and/or data |
Description of mutations |
| 1 | TRGV1-1 | F | TRGV1-1*01 | AY644517 | + | c69 |t84 D28 |a152 Q51 | a181, T61 | a216, K72 | |
| TRGV1-1 | (F) | TRGV1-1*02 | Holstein | D16119 | |t84>a, D28>E| a152>g, Q51>R|a181>t T61>S |a216>t, K72N| | ||
| TRGV1-1 | (F) | TRGV1-1*03 | Holstein | D16131 | c69>t | ||
| 2 | TRGV2-1 | F | TRGV2-1*01 | Holstein | AY644517 | + | |
| 3 | TRGV3-1 | F | TRGV3-1*01 | NW_937068 | + | t44, V15| g65, R22| g84 |c101, T34|g139, D47|g216 | | |
| TRGV3-1 | (F) | TRGV3-1*02 | Brown Swiss | U73187 | t44>c, V15>A| g65>a, R22>H| g84>a |c101>t, T34>I|g139>a, D47>N|g216>a | | ||
| TRGV3-2 | F | TRGV3-2*01 | Brown Swiss | NW_937068 | + | t161, V54| t204, N68| c265, t267 | |
| TRGV3-2 | (F) | TRGV3-2*02 | Brown Swiss | U73186 | t161>c, V54>A| t204>a, N68>K| c265>t, t267>g | 4 | TRGV4-1 | (F) | TRGV4-1*01 | DQ179592 |
| 5 | TRGV5-1 | F | TRGV5-1*01 | AY644518 | + | c2, S1 |a30, L10 |t45 | g60 |c63, F21 |c87 |a125, |g144 |c148, c150, P50|c151 |g155, R52| c157, L53| a167, Y56|g169, D57|t231, H77| c287, A96|t312 | | |
| TRGV5-1 | (F) | TRGV5-1*02 | DQ179595 | a125>g, Y42>C| a167>g, Y56>C|t312>c | |||
| TRGV5-1 | (F) | TRGV5-1*03 | Holstein | D13653 | c2>a, S1>Y |g60>c |t231>a, H77>Q| | ||
| TRGV5-1 | (F) | TRGV5-1*04 | Holstein | D16125 | a30>c, L10>F |c63>g, F21>L |g144>t |g155>t, R52>L|g169>t, D57>Y| | ||
| TRGV5-1 | (F) | TRGV5-1*05 | Holstein | D16130 | t45>a |c87>a |c148>a, c150>a, P50>T|c151>a |c157>a, L53>I|t231>a, H77>Q|c287>a, A96>E|c287>a, A96>E | ||
| TRGV5-2 | (F) | TRGV5-2*01 | AY644518 | + | a30, L10| t45 | c63, F21|a71, D24| c117| g155, R52| c168 |g159, D57| g187, A63| t189 |t205, S69| c221, T74|a239 , K80 |c258, S86|a268, T90| g274, V92|c297 |c300 | | ||
| TRGV5-2 | (F) | TRGV5-2*02 | Holstein | D16122 | c258>g, S86>R| | ||
| TRGV5-2 | (F) | TRGV5-2*03 | Holstein | D13653 | g187>a, A63>T| | ||
| TRGV5-2 | (F) | TRGV5-2*04 | Holstein | D16125 | c63>g, F21>L|a30>c, L10>F| g155>t, R52>L|c168>t |g159>t, D57>Y| | ||
| TRGV5-2 | (F) | TRGV5-2*05 | Holstein | D16127 | a30>c, L10>F|g155>t, R52>L|g159>t, D57>Y|a268, T90|g274, V92| | ||
| TRGV5-2 | (F) | TRGV5-2*06 | Holstein | D16127 | c258, S86|c300>g | | ||
| TRGV5-2 | (F) | TRGV5-2*07 | Holstein | D16127 | a71>c, D24>A| c168>t | c221>g, T74>R| c300>g | | ||
| TRGV5-2 | (F) | TRGV5-2*08 | Holstein | D16127 | c168>t |c297>c| t45>a | c117>t| | ||
| TRGV5-2 | (F) | TRGV5-2*09 | Holstein | D16127 | a30>c, L10>F|t45>a | c117>t| t189>del#|237^238>inst# |a239>t, K80>M | c258>g, S86>R| | ||
| TRGV5-2 | (F) | TRGV5-2*10 | Holstein | D16127 | a30>c, L10>F| t189>del# |c168>t |t205>g, S69>A|237^238>inst#| a239>t, K80>M | | ||
| 6 | TRGV6-1 | F | TRGV6-1*01 | AY644518 | + | a42 |a55, I19 |c61, L21|g80, R27| g139, G47| a260, Y87| g285 |t307, Y103| | |
| TRGV6-1 | (F) | TRGV6-1*02 | Holstein | DQ179597 | a42>g |a55>c, I19>L |c61>a, L21>M|g80>a, R27>K| g139>a, G47>S| a260>g, Y87>C| g285>a |t307c, Y103>H| | ||
| TRGV6-2 | F | TRGV6-2*01 | AC172685 | + | |||
| 7 | TRGV7-1 | F | TRGV7-1*01 | NW_937068 | + | c315 | |
| TRGV7-1 | (F) | TRGV7-1*02 | AY735449 | c315>t | |||
| 8 | TRGV8-1 | F | TRGV8-1*01 | AY644517 | + | ||
| TRGV8-2 | (F) | TRGV8-2*01 | AY644517 | + | g42 | ||
| TRGV8-2 | (F) | TRGV8-2*02 | DQ179600 | + | g42>t | ||
| TRGV8-3 | F | TRGV8-3*01 | AY644517 | + | g42 |g66, E22|t75 |g145, V49|g151, G51|c156 |c258, S86|c263, a264, T88|t265, F89| c302, T101| t315 | | ||
| TRGV8-3 | (F) | TRGV8-3*02 | Holstein | D13648 | g42>t |g66>t, E22>D|t75>c |g145>c, V49>L|g151>c, G51>R|c156>t |c258>g, S86>R|c263>g, a264>t, T88>S|t265>g, F89>V| c302>t, T101>I| t315>c | | ||
| TRGV8-4 | F | TRGV8-4*01 | AY644517 | + | |||
| 9 | TRGV9-1 | F | TRGV9-1*01 | AY644517 | + | ||
| TRGV9-2 | F | TRGV9-2*01 | AY644517 | + | |||
| 10 | TRGV10-1 | F | TRGV10-1*01 | NW_937068 | + |
Created:29-Jun-2011
Last Updated:Friday, 22-Sep-2023 18:30:59 CEST
Author: Joumana Jabado-Michaloud and Elodie Foulquier
Editor: Chantal Ginestoux
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