Functionality is shown between parentheses, (F) and (P), when the accession number refers to rearranged genomic DNA or cDNA and the corresponding germline gene has not yet been isolated.
The IMGT allele table refers to the V-REGION polymorphism. It does not include polymorphisms in the other parts of the V-GENE. V-REGION alleles are only described for genes which have at least one Functional or ORF allele. The accession number of a reference sequence is given for each allele.
Click on a gene name to get the alignment of the corresponding V-REGION alleles.
Click on an accession number to get the sequence and additional information (IMGT annotations, IMGT flat file, Coding regions...).
| IGHV
subgroup |
IGHV gene name |
Fct | IGHV
allele name |
Accession numbers | Confirmed by genetics and/or data |
Description of mutations |
| IGHV1 | IGHV1S1 | F | IGHV1S1*01 | U09719 | ||
| IGHV1S2 | F | IGHV1S2*01 | AF068137 | |||
| IGHV1S3 | (F) | IGHV1S3*01 | AF068137 | |||
| IGHV1S4 | (F) | IGHV1S4*01 | M27230 | |||
| IGHV1S5 | (F) | IGHV1S5*01 | M58673 | |||
| IGHV1S6 | (F) | IGHV1S6*01 | U67437 | |||
| IGHV1S7 | (F) | IGHV1S7*01 | U67439 | |||
| IGHV1S8 | (F) | IGHV1S8*01 | AF161275 | |||
| IGHV1S9 | (F) | IGHV1S9*01 | AF161276 | |||
| IGHV1S10 | (F) | IGHV1S10*01 | AF161278 | |||
| IGHV1S12 | (F) | IGHV1S12*01 | AY238358 | |||
| IGHV2 | IGHV2S2 | (F) | IGHV2S2*01 | M58671 | ||
| IGHV2S3 | (F) | IGHV2S3*01 | M58670 | |||
| IGHV2S4 | (F) | IGHV2S4*01 | M58675 | |||
| IGHV2S5 | (F) | IGHV2S5*01 | U67441 | |||
| IGHV2S6 | (F) | IGHV2S6*01 | AF161279 | |||
| IGHV2S7 | (F) | IGHV2S7*01 | AY238359 | |||
| IGHV3 | IGHV3S1 | F | IGHV3S1*01 | U09721 | ||
| IGHV3S2 | F | IGHV3S2*01 | AF068137 | |||
| IGHV3S3 | (F) | IGHV3S3*01 | M58672 | |||
| IGHV3S4 | (F) | IGHV3S4*01 | M58699 | |||
| IGHV3S5 | (F) | IGHV3S5*01 | U67442 | |||
| IGHV3S6 | (ORF) | IGHV3S6*01 | AF161272 | |||
| IGHV3S7 | (F) | IGHV3S7*01 | AF161273 | |||
| IGHV3S8 | (F) | IGHV3S8*01 | AF161274 | |||
| IGHV3S9 | (F) | IGHV3S9*01 | AF161277 | |||
| IGHV3S10 | (F) | IGHV3S10*01 | AY238360 | |||
| IGHV4 | IGHV4S1 | F | IGHV4S1*01 | U09722 | ||
| IGHV4S2 | (F) | IGHV4S2*01 | M58668 | |||
| IGHV4S3 | (F) | IGHV4S3*01 | U67443 | |||
| IGHV4S4 | (F) | IGHV4S4*01 | AF161282 | |||
| IGHV5 | IGHV5S2 | (F) | IGHV5S2*01 | M58674 | ||
| IGHV5S3 | (F) | IGHV5S3*01 | U67444 | |||
| IGHV5S4 | (F) | IGHV5S4*01 | AF161281 | |||
| IGHV5S5 | (F) | IGHV5S5*01 | AY238361 | |||
| IGHV6 | IGHV6S1 | F | IGHV6S1*01 | U09724 | ||
| IGHV6S2 | (F) | IGHV6S2*01 | M64400 | |||
| IGHV6S3 | (F) | IGHV6S3*01 | U67445 | |||
| IGHV6S4 | (F) | IGHV6S4*01 | AF161271 | |||
| IGHV6S5 | (F) | IGHV6S5*01 | AF161280 | |||
| IGHV6S6 | (F) | IGHV6S6*01 | AY238362 | |||
| IGHV7 | IGHV7S2 | (F) | IGHV7S2*01 | U34411 | ||
| IGHV7S3 | (F) | IGHV7S3*01 | U34410 | |||
| IGHV7S4 | (F) | IGHV7S4*01 | U67446 | |||
| IGHV7S5 | (F) | IGHV7S5*01 | AY238363 | |||
| IGHV7S6 | (F) | IGHV7S6*01 | AY238364 | |||
| IGHV7S7 | (F) | IGHV7S7*01 | AY238375 | |||
| IGHV8 | IGHV8S1 | F | IGHV8S1*01 | AY238377 | ||
| IGHV8S2 | (F) | IGHV8S2*01 | AY238365 | |||
| IGHV8S3 | (F) | IGHV8S3*01 | AY238366 | |||
| IGHV8S4 | (F) | IGHV8S4*01 | AY238376 | |||
| IGHV9 | IGHV9S1 | F | IGHV9S1*01 | AY238378 | ||
| IGHV9S2 | (F) | IGHV9S2*01 | AY238367 | |||
| IGHV9S3 | (F) | IGHV9S3*01 | AY238368 | |||
| IGHV10 | IGHV10S1 | P | IGHV10S1*01 | AY238379 | ||
| IGHV10S2 | (F) | IGHV10S2*01 | AY238369 | |||
| IGHV10S3 | (F) | IGHV10S3*01 | AY238370 | |||
| IGHV11 | IGHV11S2 | (F) | IGHV11S2*01 | AY238371 | ||
| IGHV11S3 | (F) | IGHV11S3*01 | AY238372 | |||
| IGHV12 | IGHV12S1 | F | IGHV12S1*01 | AY238381 | ||
| IGHV12S2 | (F) | IGHV12S2*01 | AY238373 |
Created: 06/05/2002
Last updated: Friday, 22-Sep-2023 18:31:01 CEST
Author: Nathalie Bosc
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