D-REGION alleles are only described at the nucleotide level since D-REGION can be used in the three reading frames. The numbering starts with the first nucleotide downstream the 5'D-HEPTAMER. The accession number of a reference sequence is given for each allele.
Click on a gene name to get the alignment of the corresponding D-REGION alleles.
Click on an accession number to get the sequence and additional information (IMGT annotations, IMGT flat file, Coding regions...).
IGHD subgroup | IGHD gene name |
Fct | IGHD allele name | Strain | Accession number | confirmed by genetics and/or data | Description of mutations |
1 | FL16.1 | F | D-FL16.1*01 | BALB/c | J00434 | + | c11 |a15 | | F | D-FL16.1*02 | A/J | M35332 | c11>t|a15>g| | FL16.2 | F | D-FL16.2*01 | BALB/c | J00436 |
2 | SP2.x | F | D-SP2.x*01 | C57BL/6J | M60961 | SP2.1 | F | D-SP2.1*01 | C57BL/6J | M60955 | + | SP2.2 | F | D-SP2.2*01 | BALB/c | J00431 | + | SP2.3 | F | D-SP2.3*01 | BALB/c | J00435 | + | SP2.4 | F | D-SP2.4*01 | BALB/c | J00437 | SP2.5 | F | D-SP2.5*01 | BALB/c | J00432 | + | SP2.6 | F | D-SP2.6*01 | BALB/c | J00433 | SP2.7 | F | D-SP2.7*01 | BALB/c | J00438 | + | SP2.8 | F | D-SP2.8*01 | BALB/c | J00439 | + | SP2.9 | F | D-SP2.9*01 | BALB/c | D13199 | + |
3 | ST4 | F | D-ST4*01 | BALB/c | M23243 | ||
4 | Q52 | F | D-Q52*01 | BALB/c | L32868 | t2 | | F | D-Q52*02 | BALB/c | J00440 | t2>del| |
Created: 09/03/2000
Author: Géraldine Folch