Table of alleles: Zebrafish (Danio rerio) IGHV

Functionality is shown between parentheses, (F) and (P), when the accession number refers to rearranged genomic DNA or cDNA and the corresponding germline gene has not yet been isolated.

The IMGT allele table refers to the V-REGION polymorphism. It does not include polymorphisms in the other parts of the V-GENE. V-REGION alleles are only described for genes which have at least one Functional or ORF allele. The accession number of a reference sequence is given for each allele.

Click on a gene name to get the alignment of the corresponding V-REGION alleles.
Click on an accession number to get the sequence and additional information (IMGT annotations, IMGT flat file, Coding regions...).

Germline genomic sequences are needed to confirm if the nucleotide substitutions result from somatic mutations or correspond to allelic polymorphisms.

IGHV gene name Fct IGHV
allele name
Accession numbers Confirmed
Description of mutations
1 1S1 F V1S1*01 AF273897 + t60  |t89  ,M30  |c93  ,S31  |c96  |
(F) V1S1*02 AF273899   t60>a|t89>a,M30>K|c93>g,S31>R|c96>t|
1S2 (F) V1S2*01 AF273880   g95  ,S32  |t116  ,M39  |g139  ,G47  |g161  ,G54  |a166  ,t168  ,I56  |c183  |
(F) V1S2*02 AF273886                                                     |a166>t,t168>g,I56>L|
(F) V1S2*03 AF273889              |t116>c,M39>T|
(F) V1S2*04 AF273891                                                                         |c183>a|
(F) V1S2*05 AF273902   g95>c,S32>T|            |g139>a,G47>R|g161>t,G54>V| 
1S3 (F) V1S3*01 AF273890   c65  ,S22  |c71  ,T24  |t84  |g92  ,S31  |g96  ,R32  |c99  |t165  |t174  |g203  ,G68  |c243  ,D81  |
(F) V1S3*02 AF273900                          |t84>c|                             |t165>c|t174>c|            |c243>g,D81>E|
(F) V1S3*03 AF273901              |c71>t,T24>I|t84>c|           |g96>t,R32>S|                   |g203>c,G68>A|
(F) V1S3*04 AF273894 +                        |t84>c|g92>a,S31>N|           |c99>t|             |g203>c,G68>A|
(F) V1S3*05 AF273893   c65>a,S22>Y|           |t84>c|g92>a,S31>N|           |c99>t|             |g203>c,G68>A|
1S4 (F) V1S4*01 AF273892   g279  ,R93  |
(F) V1S4*02 AF273896   g279>c,R93>S|
2 2S1 (F) V2S1*01 AF273879 + g187  ,A63  |t279  ,S93  |
(F) V2S1*02 AF273887   g187>a,A63>T|t279>a,S93>R|
3 3S1 (F) V3S1*01 AF273883 +  
4 4S1 (F) V4S1*01 AF273876   c93  |t203  ,V68  |g227  ,G76  |a235  ,T79  |
(F) V4S1*02 AF273884                                  |a235>t,T79>S|
(F) V4S1*03 AF273877   c93>t|t203>c,V68>A|g227>c,G76>A|
4S2 (F) V4S2*01 AF273882   a15  |g244  ,D82  |
(F) V4S2*02 AF273885   a15>g|g244>a,D82>N|
4S3 (F) V4S3*01 AF273878    

Created: 15/11/2001
Author: Nathalie Bosc