Assignment of rearranged cDNAs and gDNAs to germline genes: Mouse (Mus musculus) TRBV

In this table are listed representative rearranged complementary DNAs (cDNAs) and genomic DNAs (gDNAs).

Rearranged cDNAs (#c) and gDNAs (#g) TRBV sequences have been assigned to IMGT TRBV genes and alleles as described in Germline gene tables, Alignments of alleles and Tables of alleles. Assignments were performed using IMGT/V-QUEST.

TRBV
gene name
Reference sequences Rearranged cDNAs and gDNAs CDR lengths
Allele name Accession
number
Clone name Strain Accession numbers
1 TRBV1*01 AE000663 AR1 C57L X02780 [1]#c [6.6. ]
  C57BL/6 M13671 [2]p5'#c [6.6. ]
BDFL5.2 C57BL/6 x DBA/2 (F1) X03670 [6]#g [6.6. ]
BDFL C57BL/6 x DBA/2 (F1) X03762 [6]p5'#g [6.6. ]
18.2A10 B10.A M22605 [20]#g [6.6. ]
AR-5 BALB/c x A/J (F1) M21203 [36]#g [6.6. ]
18N.30 CBA/J M26421 [15]p5'#c [x.x. ]
MT1-6 BALB/c M34203 [35]p5'#c [x.6. ]
TRBV1*02 X01642 #c E1 BALB/c X01642 [26]#c [6.6. ]
2 TRBV2*01 AE000663 TB3 C57BL/Ka X02781 [1]#c [5.6. ]
  C57BL/6 M13674 [2]#c [5.6. ]
42H11 C57BL/6 M16122 [32]#c [5.6. ]
52H10F11 B6.C-H2bm12 M16121 [32]#c [5.6. ]
MT1-14 BALB/c M34199 [35]#c [5.6. ]
BB02 C57BL/10 X54322 [18]#g [5.6. ]
3 TRBV3*01 AE000663 BDFL3.2 C57BL/6 x DBA/2 (F1) X03671 [6]#g [5.6. ]
SJL4 SJL M11860 [3]#c [5.6. ]
TRBV3*02 X03865 #c 4.C3 B10.A X03865 [7]#c [5.6. ]
B10 B10.A X03864 [7]#c [5.6. ]
4 TRBV4*01 X56725   BALB/c M13678 [2]p5'#c [x.6. ]
MT1-27 BALB/c M34201 [35]p5'#c [x.6. ]
CTL8 C57BL/6 X56702 [13]#c [5.6. ]
B5-10 C57BL/6 X56704 [13]#c [5.6. ]
B11-5 C57BL/6 X56706 [13]#c [5.6. ]
B10-4 C57BL/6 X56709 [13]#c [5.6. ]
B12-1 C57BL/6 X56710 [13]#c [5.6. ]
B13-2 C57BL/6 X56711 [13]#c [5.6. ]
B615-1 C57BL/6 X56714 [13]#c [5.6. ]
B7-15.19 C57BL/6 X56715 [13]#c [5.6. ]
TRBV4*02 AJ249819 #c SWR-10 SWR/J AJ249819 [34]#c [5.6. ]
5 TRBV5*01 AE000663 A20.2.15 BALB/c x C57BL/6 (F1) M11456 [24]#c [5.6. ]
1.9.2 B10.A[5R] X02778 [1]#c [5.6. ]
37.2A10 B10.A M22606 [20]#g [5.6. ]
BW14 AKR M20177 [19]#g [5.6. ]
TRBV5*02 X00438 #c 86T1 BALB/c X00438 [12]#c [5.6. ]
6.9R.D6 B10.S[9R] M20877 [21]#c [5.6. ]
TRBV5*03 X02779 #c BW5147 AKR X02779 [1]#c [5.6. ]
  C57BL/6 M13676 [2]#c [5.6. ]
TRBV5*04 M20878 #c 7.9R.1F8 B10.S[9R] M20878 [21]#c [5.6. ]
TRBV5*05 AJ249820 #c SWR-1 SWR/J AJ249820 [34]#c [5.6. ]
12-1 TRBV12-1*01 M15614 5/10-20D C57BL/10 X05737 [14]#c [5.6. ]
BW12 AKR M20136 [19]#g [5.6. ]
LH8-1 C57BL/6 M21673 [23]#g [5.6. ]
A2.2B2 B10.A M26420 [15](1)p5'#c [x.x. ]
B2-13 C57BL/6 X56718 [13]#c [5.6. ]
TRBV12-1*02 M30881 #c NZW22S NZW M30881 [4]#c [5.6. ]
12-2 TRBV12-2*01 M15613   C57BL/6 M13673 [2]#c [5.6. ]
NB3 BALB/c nu/nu M27349 [17]#c [5.6. ]
LH8-2 C57BL/6 M21674 [23]#g [5.6. ]
TRBV12-2*02 X02782 #c TB21 BALB/c X02782 [1]#c [5.6. ]
13-1 TRBV13-1*02 AE000663 TB23 BALB/c X02785 [1]#c [5.6. ]
2B11 BALB/c M34219 [35]#c [5.6. ]
13-2 TRBV13-2*01 M15617 TB2 C57BL/Ka X02784 [1]#c [5.6. ]
  BALB/c M13669 [2]#c [5.6. ]
B6.2.16 C57BL/6 M19404 [38]#c [5.6. ]
V2.1 BALB/c M34205 [35](2)p5'#c [x.6. ]
TRBV13-2*02 M27350 #c NB1 BALB/c nu/nu M27350 [17]#c [5.6. ]
TRBV13-2*03 M26417 #c 3A9 CBA/J M26417 [15]#c [5.6. ]
TRBV13-2*04 AJ249823 #c   CI27 AJ249823 [28]#c [5.6. ]
TRBV13-2*05 AJ250103 #c   ER34 AJ250103 [28]#c [5.6. ]
13-3 TRBV13-3*01 M15616 C5 C57BL/6 X01641 [26]#c [5.6. ]
TB12 C57BL/Ka X02783 [1]#c [5.6. ]
P14B.1 B10.BR X06772 [27]#c [5.6. ]
14 TRBV14*01 AE000664   C57BL/6 M13675 [2]p5'#c [x.x. ]
Vb12H6 C57BL/6 M25913 [22]#c [5.6. ]
BVI/5 CBA/J M31648 [11]#c [5.6. ]
15 TRBV15*01 AE000664   C57BL/6 M13672 [3]p5'#c [x.x. ]
NZW8 NZW M30880 [4]p5'#c [x.6. ]
16 TRBV16*01 L29434 F3-42 C57BL/6 X04331 [5]#c [5.6. ]
B5-46 C57BL/6 X56708 [13]#c [5.6. ]
TRBV16*02 M13670 #c   C57BL/6 M13670 [2]#c [5.6. ]
TRBV16*03 M15459 #c AK1 C57BL/6 M15459 [30]#c [5.6. ]
TRBV16*04 X14388 #c F5 C57BL/6 X14388 [25]#c [5.6. ]
17 TRBV17*01 AE000664   BALB/c M13677 [2]#c [5.6. ]
19 TRBV19*01 AE000664   BALB/c M10093 [2]#c [5.6. ]
3F9 BALB/c M29841 [29]#c [5.6. ]
M3 C57BL/6 M12434 [10]#g [5.6. ]
C9 C57BL/6 me/me X05738 [14]#c [5.6. ]
5.3.18 B6.C-H2bm12 M16120 [32]#c [5.6. ]
TRBV19*02 X01643 #c LB2 C57BL/6 X01643 [26]#c [5.6. ]
TRBV19*03 AJ249821 #c SWR-6 SWR/J AJ249821 [34]#c [5.6. ]
20 TRBV20*01 AE000664 FN1-18 C57BL/6 X04047 [8]#c [6.7. ]
TRBV20*02 M11859 #c SJL73 SJL M11859 [3]#c [6.7. ]
24 TRBV24*03 M16203 #g PEMBL8 BALB/c M16203 [16]#g [5.6. ]
  B10.Q M22007 [39]#c [5.6. ]
TRBV24*04 L48997 #g SF17 CzechII L48997 [37]#g [5.6. ]
26 TRBV26*01 K02548 3H.25 C57BL/6 M12415 [9]#g [5.6. ]
C.F.6 B10.A X03862 [7]#c [5.6. ]
5C.C7 B10.A X03863 [7]#c [5.6. ]
A4.A1 B10.A M26419 [15](1)p5'#c [x.x. ]
B413-2.3 C57BL/6 X56713 [13]#c [5.6. ]
TRBV26*02 AJ249822 #c SWR-3 SWR/J AJ249822 [34]#c [5.6. ]
29 TRBV29*01 AE000664 5/10-20K C57BL/10 X05735 [14](1)p5'#c [x.6. ]
TRBV29*02 X00696 #c pHDS11 BALB/c X00696 [32]#c [5.6. ]
30 TRBV30*01 X16695 pMlpr2 MRL lpr/lpr M14294 [33]p5'#c [x.7. ]
31 TRBV31*01 X03277 SJL33 SJL M11858 [3]#c [6.5. ]
TRBV31*02 M26418 #c C11.A2 B10.A M26418 [15]#c [6.5. ]
p5': partial in 5' (more than 10 amino acids missing in 5')
#c: rearranged cDNA, #g: rearranged genomic DNA

IMGT notes:
(1)The sequence being partial, it is not possible to decide if the gene belongs to allele *01 or *02.
(2)The sequence being partial, it is not possible to decide if the gene belongs to allele *01 or *03.

References:
[1] Barth, R.K. et al., Nature, 316, 517-523 (1985).
[2] Behlke, M.A. et al., Science, 229, 566-570 (1985).
[3] Behlke, M.A. et al., Nature, 322, 379-382 (1986).
[4] Behlke, M.A. et al., Proc. Natl. Acad. Sci. USA., 83, 761-771 (1986).
[5] Chou, H.S. et al., EMBO J., 5, 2149-2155 (1986).
[6] Dembic, Z. et al., Nature, 320, 232-238 (1986).
[7] Fink, P.J. et al., Nature, 321, 219-226 (1986).
[8] Gascoigne, N.R. et al., J. Exp. Med., 164, 113-130 (1986).
[9] Goverman, J. et al., Cell, 40, 589-867 (1985).
[10] Hagiya, M. et al., J. Immunol., 136, 2697-2700 (1986).
[11] Heuer, J. et al., J. Immunol., 146, 775-782 (1991).
[12] Hedrick, S.M. et al., Nature, 308, 153-158 (1984).
[13] Hirama, T. et al., Eur. J. Immunol., 21, 483-488 (1991).
[14] Iwamoto, A. et al., J. Exp. Med., 165, 591-600 (1987).
[15] Johnson, N.A. et al., J. Immunol., 142, 3298-3304 (1989).
[16] Kappler, J.W. et al., Cell, 49, 263-271 (1987).
[17] Kishihara, K. et al., Eur. J. Immunol., 17, 477-482 (1987).
[18] Kraig, E. et al., Nucleic Acid Res., 18, 5881-5881 (1990).
[19] Lee, N.E. et al., J. Immunol., 140, 1665-1695 (1988).
[20] Malissen, M. et al., Nature, 319, 28-33 (1986).
[21] Mc Elligott, D.L. et al., J. Immunol., 140, 4123-4131 (1988).
[22] Moharan, G. et al., Immunogenetics, 30, 311-313 (1989).
[23] Mori, L. et al., Immunogenetics, 28, 136-138 (1988).
[24] Morinaga, T. et al., Proc. Natl. Acad. Sci. U.S.A., 82, 8163-8167 (1985).
[25] Palmer, M.S. et al., Nucleic. Acid. Res., 17, 2353 (1989).
[26] Patten, P. et al., Nature, 312, 40-46 (1984).
[27] Pircher, H. et al., Eur. J. Immunol., 17, 1843-1846 (1987).
[28] Pullen, A.M. et al., J. Exp. Med., 171, 49-62 (1990).
[29] Rupp, F. et al., Nature., 315, 425-427 (1987).
[30] Rinaldy, A. et al., Immunogenetics, 36, 67-69 (1992).
[31] Saito, H. et al., Nature, 309, 757-762 (1984).
[32] Sherman, D.H., et al., Mol. Cell. Biol., 7, 1867-1872 (1987).
[33] Singer, P.A. et al., Proc. Natl. Acad. Sci. U.S.A., 83, 7018-7022 (1986).
[34] Smith, L.R. et al., J. Immunol., 144, 3234-3237 (1990).
[35] Taylor, A.H. et al., J. Exp. Med., 172, 1643-1651 (1990).
[36] Tan, K.N. et al., Cell, 54, 247-261 (1988).
[37] Tomonari, K. et al., unpublished (1996).
[38] Uematsu, Y. et al., Cell, 52, 831-841 (1988).
[39] Wade, T. et al., J. Immunol., 141, 2165-2167 (1988).


Created: 09/03/2000
Author: Nathalie Bosc