Vertical red lines indicate the localization of the TRG locus at 7p14 and
that of the TRB locus at 7q34.
Blue arrows indicate the orientation 5' → 3' of the loci, and the gene group order in the loci. Note that the TRBV gene localized at the 3' end of the TRB locus is in inverted orientation of transcription (shown by a small black arrow). The blue arrows are proportional to the size of the loci, indicated in kilobases (kb). The total number of genes in the loci are shown between parentheses.
The orientation of the loci has been determined by the analysis of translocations, involving the TRB and the TRG loci, in leukemia and lymphoma and the analysis of chromosome 7 inversions inv(7)(p14-q34), involving the TRG and TRB loci in ataxia telangiectasia patients, and in leukemia.