IMGT Repertoire (IG and TR)

Fct: FUNCTIONALITY
- F: Functional
- P: Pseudogene
- ORF: Open Reading Frame
T: Transcribed
Pr: Translated into protein

"+" or "-" indicates if the gene sequences have been found (+) or not been found (-) transcribed (T) and/or translated into protein (Pr). Arbitrarily that information is shown on the first line of each gene when the data have been confirmed by several studies.

Functionality is shown between parentheses, (F) and (P), when the accession number refers to rearranged genomic DNA or cDNA and the corresponding germline gene has not yet been isolated.
Functionality is shown between brackets, [F] and [P], when the accession number refers to genomic DNA, but not known as being germline or rearranged.

Click on:

IMGT gene name to get the corresponding IMGT/GENE-DB entry,
IMGT allele name to see the corresponding Alignments of alleles,
accession number to get the corresponding IMGT/LIGM-DB entry.

IMGT gene name	IMGT allele name	Fct	T	Pr	Positions in the locus	IMGT/LIGM-DB reference sequences							IMGT/LIGM-DB sequences from the literature
IMGT gene name	IMGT allele name	Fct	T	Pr	Positions in the locus	Strain	Clone names	Exons	Accession numbers	Positions in the sequence	Secondary accession numbers		Strain				Clone names	Accession numbers	Positions in the sequence
	IGHM	IGHM*01	(F)							cSg 5.1	CH1		X58870	[1]		c (s)
											CH2		X58870	[1]		c (s)
											CH3	(1)	X58870	[1]		c (s)
											CH4	(1)	X58870	[1]		c (s)
		IGHM*02	(F)								CH1
											CH2
										cSg F.1	CH3	(1)	X58871	[1]	(2)	c (m)
											M1	(1)	X58871	[1]	(2)	c (m)
											M2		X58871	[1]	(2)	c (m)
		IGHM*03	(F)							D39	CH1	(3)	AF155199	[2]		c (m)				V105	AF155202	[2]		c (m)
										D39	CH1	(3)	AF155199	[2]		c (m)				V10	AF155203	[2]	(5)	c (m)
										V107	CH2		AF155198	[2]	(4)	c (s)
											CH3		AF155198	[2]	(4)	c (s)
											CH4		AF155198	[2]	(4)	c (s)
	IGHD	IGHD*01	(F)							D39	CH1	(3)	AF155199	[2]		c (m)
											CH2		AF155199	[2]		c (m)
											H		AF155199	[2]		c (m)
											CH1D		AF155199	[2]		c (m)
											CH2D		AF155199	[2]		c (m)
											CH7		AF155199	[2]		c (m)
											M		AF155199	[2]		c (m)
		IGHD*02	(F)							V105	CH1	(3)	AF155202	[2]		c (m)
											CH2		AF155202	[2]		c (m)
											H		AF155202	[2]		c (m)
											CH1D		AF155202	[2]		c (m)
											CH2D		AF155202	[2]		c (m)
											CH7		AF155202	[2]		c (m)
											M		AF155202	[2]		c (m)
		IGHD*03	(F)							V10	CH1	(3)	AF155203	[2]	(5)	c (m)				D25	AF155204	[2]	(6)	c (m)
										D25	CH2		AF155204	[2]	(6)	c (m)				V10	AF155203	[2]	(5)	c (m)
										D25	H		AF155204	[2]	(6)	c (m)

c: cDNA sequence.
(s) Transcript of a secreted chain.
(m) Transcript of a membrane chain.

IMGT notes:

(1) CH3 is spliced to CH4 in secretory mu cDNA, whereas it is spliced to the M1 exon in membrane mu cDNA (see [1]).
(2) Partial C-REGION: partial CH3 in 5'.
(3) CH1 mu is spliced to CH1 delta in delta cDNA (see [2]).
(4) Partial C-REGION: no CH1 and partial CH2 in 5'.
(5) Partial C-REGION: only CH1 mu, CH1 and CH2 delta are present, and partial CH2 in 3'.
(6) Partial C-REGION: only CH1, CH2 and H delta are present, and partial H in 3'.

IMGT references:

[1] Bengtén E. et al., Eur. J. Immunol., 21, 3027-3033 (1991). PMID:1748150
[2] Stenvik J. and Jorgensen T.O., Immunogenetics, 51, 452-461 (2000). PMID:10866112

See also (IMGT Scientific chart):

Created:: 29/04/1999
Last updated:: 22/09/2023
Authors:: Sylvaine Artero, Nathalie Bosc

IMGT Repertoire (IG and TR)

Gene table: Atlantic cod (Gadus morhua) IGHC