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"+" or "-" indicates if the gene sequences have been found (+) or not been found (-) transcribed (T) and/or translated into protein (Pr). Arbitrarily that information is shown on the first line of each gene when the data have been confirmed by several studies.

Functionality is shown between parentheses, (F) and (P), when the accession number refers to rearranged genomic DNA or cDNA and the corresponding germline gene has not yet been isolated.
Functionality is shown between brackets, [F] and [P], when the accession number refers to genomic DNA, but not known as being germline or rearranged.

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IMGT gene name IMGT allele name Fct T Pr Positions in the locus IMGT/LIGM-DB reference sequences IMGT/LIGM-DB sequences from the literature
Strain Clone names Exons Accession numbers Positions in the sequence Secondary accession numbers Strain Clone names Accession numbers Positions in the sequence
IGHM IGHM*01 (F) cSg 5.1 CH1 X58870 [1] c (s)
CH2 X58870 [1] c (s)
CH3 (1) X58870 [1] c (s)
CH4 (1) X58870 [1] c (s)
IGHM*02 (F) CH1
cSg F.1 CH3 (1) X58871 [1] (2) c (m)
M1 (1) X58871 [1] (2) c (m)
M2 X58871 [1] (2) c (m)
IGHM*03 (F) D39 CH1 (3) AF155199 [2] c (m) V105 AF155202 [2] c (m)
V10 AF155203 [2] (5) c (m)
V107 CH2 AF155198 [2] (4) c (s)
CH3 AF155198 [2] (4) c (s)
CH4 AF155198 [2] (4) c (s)
IGHD IGHD*01 (F) D39 CH1 (3) AF155199 [2] c (m)
CH2 AF155199 [2] c (m)
H AF155199 [2] c (m)
CH1D AF155199 [2] c (m)
CH2D AF155199 [2] c (m)
CH7 AF155199 [2] c (m)
M AF155199 [2] c (m)
IGHD*02 (F) V105 CH1 (3) AF155202 [2] c (m)
CH2 AF155202 [2] c (m)
H AF155202 [2] c (m)
CH1D AF155202 [2] c (m)
CH2D AF155202 [2] c (m)
CH7 AF155202 [2] c (m)
M AF155202 [2] c (m)
IGHD*03 (F) V10 CH1 (3) AF155203 [2] (5) c (m) D25 AF155204 [2] (6) c (m)
D25 CH2 AF155204 [2] (6) c (m) V10 AF155203 [2] (5) c (m)
H AF155204 [2] (6) c (m)

c: cDNA sequence.
(s) Transcript of a secreted chain.
(m) Transcript of a membrane chain.

IMGT notes:
  1. (1) CH3 is spliced to CH4 in secretory mu cDNA, whereas it is spliced to the M1 exon in membrane mu cDNA (see [1]).
  2. (2) Partial C-REGION: partial CH3 in 5'.
  3. (3) CH1 mu is spliced to CH1 delta in delta cDNA (see [2]).
  4. (4) Partial C-REGION: no CH1 and partial CH2 in 5'.
  5. (5) Partial C-REGION: only CH1 mu, CH1 and CH2 delta are present, and partial CH2 in 3'.
  6. (6) Partial C-REGION: only CH1, CH2 and H delta are present, and partial H in 3'.
IMGT references:
  1. [1] Bengtén E. et al., Eur. J. Immunol., 21, 3027-3033 (1991). PMID:1748150
  2. [2] Stenvik J. and Jorgensen T.O., Immunogenetics, 51, 452-461 (2000). PMID:10866112
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Sylvaine Artero, Nathalie Bosc