IMGT Repertoire (IG and TR)

Gene table: Japanese flounder (Paralichthys olivaceus) IGHC

"+" or "-" indicates if the gene sequences have been found (+) or not been found (-) transcribed (T) and/or translated into protein (Pr). Arbitrarily that information is shown on the first line of each gene when the data have been confirmed by several studies.

Functionality is shown between parentheses, (F) and (P), when the accession number refers to rearranged genomic DNA or cDNA and the corresponding germline gene has not yet been isolated.
Functionality is shown between brackets, [F] and [P], when the accession number refers to genomic DNA, but not known as being germline or rearranged.

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IMGT gene name IMGT allele name Fct T Pr Positions in the locus IMGT/LIGM-DB reference sequences IMGT/LIGM-DB sequences from the literature
Strain Clone names Exons Accession numbers Positions in the sequence Secondary accession numbers Strain Clone names Accession numbers Positions in the sequence
IGHM IGHM*01 (F) CH1 (3) AB052744 [1] c(s)
CH2 AB052744 [1] c(s)
CH3 (1) AB052744 [1] c(s)
CH4 (1) AB052744 [1] c(s)
M1 (1)
IGHM*02 (F) CH1 (2) AB052658 [1] c
IGHM*03 (F) CH1 (3) AF226284 [2] c(s)
CH2 AF226284 [2] c(s)
CH3 (1) AF226284 [2] c(s)
CH4 (1) AF226284 [2] c(s)
IGHD IGHD*01 (F) CH1 (2) AB052658 [1] c(m)
CH2 AB052658 [1] c(m)
CH3 AB052658 [1] c(m)
CH4 AB052658 [1] c(m)
CH5 AB052658 [1] c(m)
CH6 AB052658 [1] c(m)
CH7 AB052658 [1] c(m)
M1 AB052658 [1] c(m)
M2 AB052658 [1] c(m)

c: cDNA sequence.
(s) Transcript of a secreted chain.
(m) Transcript of a membrane chain.

IMGT notes:
  1. (1) As in other Teleostei, CH3 is spliced to CH4 in secretory mu cDNA, whereas it is probably spliced to the M1 exon in membrane mu cDNA.
  2. (2) As in other Teleostei, IGHM*02 CH1 is spliced to IGHD*01 CH1 in delta cDNA. Other exons of IGHM*02 have not yet been isolated.
  3. (3) No delta cDNA spliced with IGHM*01 CH1 has been isolated (2).
IMGT references:
  1. [1] Hirono I. et al., Unpublished (2001).
  2. [2] Lee U.H. et al., Fish and Shellfish Immunol., 11, 537-540 (2001). PMID:11556482
Last updated:
Nathalie Bosc