IMGT Repertoire (IG and TR)

Fct: FUNCTIONALITY
- F: Functional
- P: Pseudogene
- ORF: Open Reading Frame
R: Rearranged
T: Transcribed
Pr: Translated into protein

"+" or "-" indicates if the gene sequences have been found (+) or not been found (-) rearranged (R), transcribed (T) and/or translated into protein (Pr). Arbitrarily that information is shown on the first line of each gene when the data have been confirmed by several studies.

Functionality is shown between parentheses, (F) and (P), when the accession number refers to rearranged genomic DNA or cDNA and the corresponding germline gene has not yet been isolated.
Functionality is shown between brackets, [F] and [P], when the accession number refers to genomic DNA, but not known as being germline or rearranged.

Click on:

IMGT gene name to get the corresponding IMGT/GENE-DB entry,
IMGT allele name to see the corresponding Alignments of alleles,
accession number to get the corresponding IMGT/LIGM-DB entry.

IMGT subgroup	IMGT gene name	IMGT allele name	Fct		Chromosomal localization	R	T	Pr	IMGT/LIGM-DB locus reference sequences						IMGT/LIGM-DB sequences from the literature
IMGT subgroup	IMGT gene name	IMGT allele name	Fct		Chromosomal localization	R	T	Pr	Breed	Clone names	Accession numbers	Positions in the sequence (L-V-GENE-UNIT)	Secondary accession numbers		Breed		Clone names	Accession numbers	Positions in the sequence (L-V-GENE-UNIT)
IGKV1	IGKV1-1	IGKV1-1*01	ORF	(1)		11				San Clemente	CM004572.1		IMGT000009	[1]	404279..404778
	IGKV1-4	IGKV1-4*01	F			11				San Clemente	CM004572.1		IMGT000009	[1]	380077..380577
	IGKV1-6	IGKV1-6*01	P	(2)		11				San Clemente	CM004572.1		IMGT000009	[1]	364543..365031
	IGKV1-7	IGKV1-7*01	P	(3)		11				San Clemente	CM004572.1		IMGT000009	[1]	353883..354784
	IGKV1-17	IGKV1-17*01	P	(4)		11				San Clemente	CM004572.1		IMGT000009	[1]	290803..291302
	IGKV1-21	IGKV1-21*01	P	(5)		11				San Clemente	CM004572.1		IMGT000009	[1]	271460..271960
IGKV2	IGKV2-8	IGKV2-8*01	F			11				San Clemente	CM004572.1		IMGT000009	[1]	350175..350909
	IGKV2-9	IGKV2-9*01	F			11				San Clemente	CM004572.1		IMGT000009	[1]	340900..341679
	IGKV2-11	IGKV2-11*01	ORF	(6)		11				San Clemente	CM004572.1		IMGT000009	[1]	334973..335776
	IGKV2-14	IGKV2-14*01	F			11				San Clemente	CM004572.1		IMGT000009	[1]	308648..309452
	IGKV2-15	IGKV2-15*01	F			11				San Clemente	CM004572.1		IMGT000009	[1]	297133..297911
	IGKV2-18	IGKV2-18*01	P	(7)		11				San Clemente	CM004572.1		IMGT000009	[1]	283725..284500
IGKV3	IGKV3-20	IGKV3-20*01	P	(8)		11				San Clemente	CM004572.1		IMGT000009	[1]	275716..276504
IGKV6	IGKV6-5	IGKV6-5*01	P	(9)		11				San Clemente	CM004572.1		IMGT000009	[1]	371602..371885	(16)
IGKV8	IGKV8-3	IGKV8-3*01	ORF	(10)		11				San Clemente	CM004572.1		IMGT000009	[1]	395561..396136
IGKV(II)	IGKV(II)-2	IGKV(II)-2*01	P	(11)		11				San Clemente	CM004572.1		IMGT000009	[1]	complement(401201..>401338)	(16)
	IGKV(II)-10	IGKV(II)-10*01	P	(12)		11				San Clemente	CM004572.1		IMGT000009	[1]	338874..339151	(16)
	IGKV(II)-12	IGKV(II)-12*01	P	(12)		11				San Clemente	CM004572.1		IMGT000009	[1]	317170..317470	(16)
	IGKV(II)-13	IGKV(II)-13*01	P	(13)		11				San Clemente	CM004572.1		IMGT000009	[1]	312558..312841	(16)
	IGKV(II)-16	IGKV(II)-16*01	P	(14)		11				San Clemente	CM004572.1		IMGT000009	[1]	295119..295413	(16)
	IGKV(II)-19	IGKV(II)-19*01	P	(15)		11				San Clemente	CM004572.1		IMGT000009	[1]	281952..282239	(16)

IMGT notes:

(1) noncanonical DONOR-SPLICE nga instead of ngt, noncanonical ACCEPTOR-SPLICE: nggnn instead of nagnn.
(2) STOP-CODON in FR1-IMGT at position AA 6, in FR3-IMGT at position AA 80.
(3) STOP-CODON in CDR1-IMGT at position AA 27, in FR2-IMGT at position AA 48 and no DONOR-SPLICE.
(4) STOP-CODON at position AA 103 in FR3-IMGT.
(5) frameshift in L-PART1.
(6) 2nd-CYS is replaced by Ser.
(7) frameshift in FR1-IMGT, no DONOR-SPLICE.
(8) frameshift in FR3-IMGT.
(9) STOP-CODON at position AA 42 in FR2-IMGT, frameshift in FR3-IMGT, no V-NONAMER.
(10) noncanonical V-HEPTAMER: cactgtt instead of cacagtg and noncanonical V-NONAMER: ataaacagt instead of acacaaacc.
(11) Truncated pseudogene not assigned to subgroups with functional genes, no L-PART1, frameshift in FR1-IMGT, no V-RS.
(12) several deletions and insertions causing frameshifts in V-REGION, no L-PART1.
(13) several deletions and insertions causing frameshifts in V-REGION, no L-PART1, no V-RS.
(14) several deletions and insertions causing frameshifts in V-REGION, no V-RS.
(15) several deletions and insertions causing frameshifts in V-REGION and in L-PART1, no V-RS.
(16) positions in V-REGION.

IMGT references:

[1] Schwartz J.C. et al. Immunogenetics 2018 May;70(5):317-326. doi: 10.1007/s00251-017-1033-3. Epub 2017 Oct 23. Free PMC Article. PMID:29063126

More information:

See also (IMGT Scientific chart):

Created:: 15/12/2017
Last updated:: 22/09/2023
Authors:: Morgane Bertignac

IMGT Repertoire (IG and TR)

Gene table: goat (Capra hircus) IGKV